Results 171 to 180 of about 928,471 (414)
Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa+13 more
wiley +1 more source
Neste trabalho foi estudada a correlação entre o perfil proteico do plasma seminal e a motilidade e viabilidade espermática em coelhos submetidos ao tratamento com vetores de expressão contendo o gene da eritropoetina (EPO) e com EPO recombinante humana.
G Urtiaga+6 more
doaj
Photohermal Microswimmer Penetrate Cell Membrane with Cavitation Bubble [PDF]
Self-propelled micromotors can efficiently convert ambient energy into mechanical motion, which is of great interest for its potential biomedical applications in delivering therapeutics noninvasively. However, navigating these micromotors through biological barriers remains a significant challenge as most micromotors do not provide sufficient ...
arxiv
Topology-dependent anomalous dynamics of ring and linear DNA are sensitive to cytoskeleton crosslinking [PDF]
Cytoskeletal crowding plays a key role in the diffusion of DNA molecules through the cell, acting as a barrier to effective intracellular transport and conformational stability required for such processes as transfection, viral infection, and gene therapy.
arxiv
Inhibition of transformation and transfection in Haemophilus influenzae Rd9 by lysogeny [PDF]
Andrzej Piekarowicz, M Siwińska
openalex +1 more source
FEM1B enhances TRAIL‐induced apoptosis in T lymphocytes and monocytes
FEM1B facilitates TRAIL‐induced apoptosis through distinct mechanisms in T lymphocytes and monocytes. In T lymphocytes, FEM1B engages with TRAF2, leading to a reduction in TRAF2 expression, which subsequently lessens TRAF2's inhibitory influence on caspase‐8.
Chenbo Yang+5 more
wiley +1 more source
Optimization of transfection of green fluorescent protein in pursuing mesenchymal stem cells in vivo
OBJECTIVE: Green Fluorescent Protein (GFP) has been used as a marker of gene expression and a single cell marker in living organisms in cell biology studies.
Pınar Elçi+5 more
doaj
Factors Affecting Transfection in Bacillus stearothermophilus [PDF]
Uldis N. Streips, N. E. Welker
openalex +1 more source
The inactivation of SLC35C1 (GDP‐fucose transporter) and enzymes involved in GDP‐fucose biosynthesis was studied. Fucose supplementation increases the level of GDP‐fucose to abnormal, millimolar values in the absence of the TSTA3 protein and SLC35C1 in contrast to the GMDS/SLC35C1 double mutant.
Edyta Skurska, Mariusz Olczak
wiley +1 more source
Significant progress has been made in the field of gene therapy, but effective treatments for brain tumors remain challenging due to their complex nature.
Ishaq N. Khan+7 more
doaj +1 more source