Results 291 to 300 of about 968,391 (388)

AAV Assembled Capsids Are Produced in Cells Blocked From Cell Cycle Progression. [PDF]

Biotechnol Bioeng
Mullick A, Morasse A, Leclerc M, Liu Z, Liu QY, Leclerc S, Momcilovic M, Viau A, Kamen AA.   +8 more
europepmc   +1 more source

ROS Activated NETosis of Bone Marrow CD55+ Intermediate Mature Neutrophils Through HIF1α‐PADI4 Pathway to Initiate Bone Aging

Advanced Science, EarlyView.
In this study, we find CD55+ neutrophils show activated NETosis within bone marrow, induce BMSC senescence and osteogenesis inhibition, finally leading to bone aging initiation. Mechanistically, ROS synergizes with the CD55‐driven HIF1α‐PADI4 pathway to promote NETosis.
Yutong Guo, Shengjie Cui, Xi Wen, Yidi Wang, Ben Wu, Yixiang Wang, Yan Gu   +6 more
wiley   +1 more source

LncRNA NBR2 affects pancreatic β-cell function in type 2 diabetes mellitus by targeting miR-646. [PDF]

Diabetol Metab Syndr
Pu M, Kong L, Li J, Su L, Chen Y.
europepmc   +1 more source

Retroviral transfection.

BioTechniques, 2012
openaire   +2 more sources

Single‐Cell RNA Sequencing of Retina Reveals Nna1 Upregulation in Myopic Diabetic Retinopathy as a Protective Factor Against Diabetic Damage

Advanced Science, EarlyView.
This study investigates a schematic overview of the mechanistic pathways. The relationship between myopia and DR has long been of clinical interest. In diabetic mice, Nna1 expression is downregulated, whereas in diabetic mice with FDM, Nna1 expression is upregulated–particularly in Müller cells–accompanied by decreased vascular endothelial growth ...
Lihui Xie, Yingjun Cai, Bolin Chen, Bowen Li, Jing Zou, Huizhuo Xu   +5 more
wiley   +1 more source

Successful Delivery of Small Non-Coding RNA Molecules into Human iPSC-Derived Lung Spheroids in 3D Culture Environment. [PDF]

Biomedicines
Schweikert A, De Santi C, Teoh XJ, Xin Yang FL, O'Sullivan E, Greene CM, Hurley K, Oglesby IK.   +7 more
europepmc   +1 more source

Calcium-activated gene transfection from DNA/poly(amic acid-co-imide) complexes

, 2015
Wu SY, Chang LT, S Peng, Tsai Hc
openalex   +1 more source

Polyethyleneimine Mediated DNA Transfection in Schistosome Parasites and Regulation of the WNT Signaling Pathway by a Dominant-Negative SmMef2

, 2013
Shuang Liang, Matty Knight, Emmitt R. Jolly   +2 more
openalex   +2 more sources

Mettl3‐Mediated m6A Modification Represents a Novel Therapeutic Target for FSGS

Advanced Science, EarlyView.
This study explores the roles of Mettl3‐induced N6‐methyladenosine (m6A) modifications in Focal segmental glomerulosclerosis (FSGS). The findings reveal that inhibition of Mettl3 results in podocyte injury by modulating the TJP1CDC42 pathway. Moreover, Administration of N6‐methyladenosine attenuates the FSGS phenotype in WT mice induced by Adriamycin ...
Fubin Zhu, Hongzhi Li, Xiang Li, Chunxiu Du, Ting Wang, Xuling Zhou, Xiaobei Xie, Yunxia Shao, Yingzhi Huang, Yanling Hu, Xinxin Guo, Bin Zhu, Shanshan Yu, Xiaoyan Zhang, Binghai Zhao   +14 more
wiley   +1 more source

PEGylation Enhances Colloidal Stability and Promotes Ligand-Mediated Targeting of LAF-Xenopeptide mRNA Complexes. [PDF]

Polymers (Basel)
Folda P, Weidinger E, Seidl J, Yazdi M, Pöhmerer J, Grau M, Minde DP, Ali M, Kimna C, Wagner E.   +9 more
europepmc   +1 more source