Results 271 to 280 of about 971,477 (354)

NPM1 Mediates mRNA Sorting into Extracellular Vesicles via Specific RNA Motif Binding and Phase Separation

Advanced Science, EarlyView.
NPM1 selectively sorts specific mRNAs into extracellular vesicles (EVs) by recognizing RNA motifs and forming phase‐separated condensates. These mRNA cargos—including EGFR—are then loaded via multivesicular bodies. This active sorting pathway, validated in EVs derived from both lung cancer cells and patient serum, reveals a specific mechanism for ...
Kaixiang Zhang, Gaoge Sun, Xiangzheng Liu, Shuai Zuo, Pengyuan Wang, Boxiao Zhan, Zhi John Lu, Hang Yin, Ying Zhang   +8 more
wiley   +1 more source

Microfluidics for cell therapy and manufacturing in oncology and regenerative medicine.

Lab Chip
Duncan JL, Arroyo JP, Davalos RV.
europepmc   +1 more source

Application analysis of transfected cell method for detecting AChR antibodies in MG patients. [PDF]

Sci Rep
Liu W, Xia Z, Hu J, Liu G, Zhou L, Xing L, Qiang Y, Lv G.   +7 more
europepmc   +1 more source

Neuid: A Novel Neuron‐Enriched LncRNA that Connects Epigenetic Gene Silencing to Alzheimer's Disease

Advanced Science, EarlyView.
ABSTRACT The increasing evidence that non‐coding RNAs can become deregulated during pathogenesis is dramatically expanding the space for drug discovery beyond the protein‐coding genome. Long noncoding RNAs (lncRNAs) are emerging as key regulators of cellular function, yet most remain uncharacterized.
Ranjit Pradhan, Zorica Petrovic, M. Sadman Sakib, Sophie Schröder, Dennis Manfred Krüger, Tonatiuh Pena, Eren Diniz, Susanne Burkhardt, Anna‐Lena Schütz, Verena Gisa, Iga Grzadzielewska, Karl Toischer, Thor D. Stein, Jan Krzysztof Blusztajn, Ivana Delalle, Jelena Radulovic, Farahnaz Sananbenesi, Andre Fischer   +17 more
wiley   +1 more source

γ-Glutamylcyclotransferase Depletion Induces p15^INK4b and p21^Cip1-mediated Senescence <i>via</i> TGF-β2/SMAD3 Pathway Activation in Breast Cancer Cells. [PDF]

Cancer Genomics Proteomics
Kubota S, Ii H, Isono T, Kusaba T, Nagasawa M, Wada A, Kobayashi K, Yamanaka K, Mori M, Taniguchi K, Nakata S, Kageyama S.   +11 more
europepmc   +1 more source

NIBV Induces Incomplete Autophagy via AMPK‐TFEB, Causing Kidney Injury in Chicks

Advanced Science, EarlyView.
This study reveals that NIBV can inhibit the nuclear translocation of TFEB by suppressing the expression of AMPK, leading to the blockade of autophagolysosomal functions, in turn increasing NIBV replication and triggering severe kidney injury in chicks.
Cheng Huang, Yizhou Zeng, Yunfeng Chen, Zhengqing Li, Salma Mbarouk Omar, Shengwei Zhong, Ping Liu, Zhanhong Zheng, Gaofeng Cai, Xiaona Gao, Xiaoquan Guo   +10 more
wiley   +1 more source

LSD1 promotes prostate cancer cell proliferation by upregulating PRAC1 expression. [PDF]

Sci Rep
Liao Y, Liu C.
europepmc   +1 more source

Peste des petit ruminants viruses (PPRV) can escape RNA interference in vitro [PDF]

, 2010
Albina, Emmanuel, Holz, Carine, Keita, Djénéba, Kwiatek, Olivier, Libeau, Geneviève, Minet, Cécile, Nizamani, Zaheer Ahmed, Servan de Almeida, Renata   +7 more
core  

miR-369-3p Modulates LRRK2-Mediated Inflammation and Autophagy in RAW264.7 Macrophages. [PDF]

Int J Mol Sci
Scalavino V, Piccinno E, Grassi I, Armentano R, Giannelli G, Serino G.   +5 more
europepmc   +1 more source

Correction: Development of a highly efficient protoplast regeneration and transfection protocol for enhancing CRISPR genome editing of <i>Brassica carinata</i>. [PDF]

Front Plant Sci
Frontiers Production Office .
europepmc   +1 more source