Results 101 to 110 of about 17,573,077 (386)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Manual control analysis of drug effects on driving performance [PDF]

, 1981
The effects of secobarbital, diazepam, alcohol, and marihuana on car-driver transfer functions obtained using a driving simulator were studied. The first three substances, all CNS depressants, reduced gain, crossover frequency, and coherence which ...
Moskowitz, H., Smiley, A., Ziedman, K.
core   +1 more source

Dispersion of the dielectric function of a charge-transfer insulator

, 2003
We study the problem of dielectric response in the strong coupling regime of a charge transfer insulator. The frequency and wave number dependence of the dielectric function $\epsilon ({\bf q},\omega)$ and its inverse $\epsilon ^{-1}({\bf q},\omega)$ is ...
A. F. Barabanov, A. Hübsch, A. S. Moskvin, A.F. Barabanov, A.F. Barabanov, E.A. Burovski, F.C. Zhang, F.H.L. Essler, G.H. Wannier, I. Egri, J. Fink, J. Fink, J. Richter, J.I. Frenkel, K. Tsutsui, L.J. Sham, L.X. Benedict, M. Rohlfing, P. Wróbel, R. Hayn, R. Neudert, R. O. Kuzian, R.O. Kuzian, S. Albrecht, S. Atzkern, S.-L. Drechsler, S.E. Schnatterly, V. Ambegaokar, W. Hanke, W. Hanke, Y.Y. Wang   +30 more
core   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Transfer functions

IOP Conference Series: Earth and Environmental Science, 2011
This chapter summarizes the different approaches used to reconstruct past environmental conditions from micropaleontological proxy data. The first group of methods involves calibration, i.e. a relationship is calculated between a given environmental variable and the abundances of the various species (e. g. regression, partial least squares). The second
openaire   +1 more source

Transfer function characteristics of super resolving systems [PDF]

Signal quality in an optical storage device greatly depends on the optical system transfer function used to write and read data patterns. The problem is similar to analysis of scanning optical microscopes.
Curtis, Craig H., Milster, Tom D.
core   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source

Mechanisms of parasite‐mediated disruption of brain vessels

FEBS Letters, EarlyView.
Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira, Sílvia Arroz‐Madeira, Cláudio A. Franco, Sara Silva Pereira   +3 more
wiley   +1 more source

Modeling the Electrical Activity of the Heart via Transfer Functions and Genetic Algorithms

Biomimetics
Although healthcare and medical technology have advanced significantly over the past few decades, heart disease continues to be a major cause of mortality globally. Electrocardiography (ECG) is one of the most widely used tools for the detection of heart
Omar Rodríguez-Abreo, Mayra Cruz-Fernandez, Carlos Fuentes-Silva, Mario A. Quiroz-Juárez, José L. Aragón   +4 more
doaj   +1 more source