Results 111 to 120 of about 2,982,596 (301)
A working model for cytoplasmic assembly of H/ACA snoRNPs
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley +1 more source
Antimicrobial resistance (AMR) is of huge importance, resulting in over 1 million deaths each year. Here, we describe how a new drug, enmetazobactam, designed to help fight resistant bacterial diseases, inhibits a key enzyme (GES‐1) responsible for AMR. Our data show it is a more potent inhibitor than the related tazobactam, with high‐level computation
Michael Beer +10 more
wiley +1 more source
On Hamiltonian rational transfer functions
This paper deals with Hamiltonian realizations for Hamiltonian transfer functions \(G(Z)=G^ T(-Z)\). After the introduction, Chapter 2 develops the theory of duality for polynomial models in symplectic spaces. This leads to an intimate study of Hamiltonian adjoints of Laurent maps.
openaire +3 more sources
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican +7 more
wiley +1 more source
Fourier Based Fast Multipole Method for the Helmholtz Equation
The fast multipole method (FMM) has had great success in reducing the computational complexity of solving the boundary integral form of the Helmholtz equation.
Cecka, Cris, Darve, Eric
core +1 more source
Novel and unscrutinized immune entities of the zebrafish gut
Understudied cells of the zebrafish immune system include bona fide immune cells and epithelial (‐derived) cells with immune functions. Research focusing on zebrafish cells which demonstrate similarities to mammalian immune cell counterparts may help us understand the pathologies in which they are implicated. Currently available and advanced tools make
Audrey Inge Schytz Andersen‐Civil +5 more
wiley +1 more source
The transfer function of general two terminal-pair RC networks [PDF]
Aaron Fialkow, Irving Gerst
openalex +1 more source
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona +4 more
wiley +1 more source
Network Synthesis: Synthesis of a Finite Four-Terminal Network from its Prescribed Driving-Point Functions and Transfer Function [PDF]
Charles M son Gewertz
openalex +1 more source
Pion electromagnetic form factor in the Covariant Spectator Theory
The pion electromagnetic form factor at spacelike momentum transfer is calculated in relativistic impulse approximation using the Covariant Spectator Theory.
Biernat, Elmar P. +3 more
core +1 more source

