Results 201 to 210 of about 168,857 (234)

NMI Regulates Adipose Adaptive Thermogenesis Through TLR4/IRF3 Signaling to Promote Obesity

Advanced Science, EarlyView.
Adipose tissue‐derived NMI is secreted under metabolic stress and suppresses adaptive thermogenesis through TLR4/IRF3 signaling, repressing the PPARα/PGC‐1α/UCP1 thermogenic transcriptional program. Genetic ablation or anti ‐ NMI monoclonal antibody treatment enhances energy expenditure, protects against DIO, and ameliorates adipose tissue inflammation,
Ting‐Ting Li, Xin‐Yuan Zhao, Min Zhang, Zhuang‐Feng Weng, Xiao‐Ran Guo, Ying‐Fang Liu, Qiao‐Ping Wang, Huan‐Huan Liang   +7 more
wiley   +1 more source

Organellar genome evolution in Camellia tianeensis (Theaceae): comparative insights into RNA editing, codon usage, and DNA transfer between chloroplast and mitochondrion. [PDF]

BMC Genomics
Ran Z, Li Z, Xiao X, Gu W, An M, Xu J, Guo Z.   +6 more
europepmc   +1 more source

The impact of psuedouridine modification on human tRNA. [PDF]

Biochem Soc Trans
Stone Y, Morgan E, Su YH, Kuo CY, Lin TY.   +4 more
europepmc   +1 more source

Mitochondrial genome of the invasive weed Amaranthus palmeri: structural features, RNA editing, and evolutionary insights. [PDF]

BMC Plant Biol
Zheng J, Bai X, Zhu T, Li A, Yan J, Li H, Qi Z, Dai S, Yan X.   +8 more
europepmc   +1 more source

State-dependent promoter switching mediates integrase gene transcription in the integrative and conjugative element ICEKp1 of Klebsiella pneumoniae. [PDF]

Nucleic Acids Res
Liu G, Huang Z, Guan J, Tai C, Shi L, Chao Y, Wang R, Wang K, Ou HY.   +8 more
europepmc   +1 more source

Mitochondrial genome assembly, comparative analysis of two caprifoliaceae species, and insights into adaptive evolution. [PDF]

BMC Plant Biol
Wang J, Ren M, Zhao M, Du H, Huang S, Wang S, Hou R, Jiang X, Yan C, Li J, Liu ZL.   +10 more
europepmc   +1 more source

NMR-Based Fragment Screening for RNA-Targeted Drug Discovery. [PDF]

Molecules
Petersen RJ, Wang Y.
europepmc   +1 more source

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A Comprehensive Repertoire of Transfer RNA-Derived Fragments and Their Regulatory Networks in Colorectal Cancer

Journal of Computational Biology, 2020
To provide systematic insight into the composition and expression of transfer RNA (tRNA) derivatives transcriptome in colorectal cancer (CRC). tRNA derivatives expression profiles in three pairs of CRC and adjacent normal colon tissues were performed by tRNA-derived small RNA fragments (tRFs) and tRNA halves (tiRNA) sequencing, and microarray data of ...
Pan Chi, Shenghui Huang, Xingrong Lu
exaly   +3 more sources

Transfer RNA‐derived fragments as potential exosome tRNA‐derived fragment biomarkers for osteoporosis

International Journal of Rheumatic Diseases, 2018
AbstractAimOsteoporosis is one of the common orthopedic diseases featured in low bone mineral density. Exosomes have been proven to be potential markers for many diseases and health problems. The roles of messenger RNAs and microRNAs in osteoporosis have been comprehensively studied; however, little research has focused on the function of plasma ...
Xiaodong Liu
exaly   +3 more sources