Results 1 to 10 of about 20,623 (115)

5′-tRF-19-Q1Q89PJZ Suppresses the Proliferation and Metastasis of Pancreatic Cancer Cells via Regulating Hexokinase 1-Mediated Glycolysis

open access: yesBiomolecules, 2023
tRNA-derived small RNAs (tDRs) are dysregulated in several diseases, including pancreatic cancer (PC). However, only a limited number of tDRs involved in PC progression are known. Herein, a novel tDR, 5′-tRF-19-Q1Q89PJZ (tRF-19-Q1Q89PJZ), was verified in
Zhirui Zeng, Shan Lei, Wenpeng Cao
exaly   +3 more sources

tRF-3017b promotes prostate cancer progression by enhancing cell proliferation, CTL resistance, and M2 macrophage polarization [PDF]

open access: yesScientific Reports
This research sought to assess the expression pattern and biological function of tRF-3017b in prostate cancer, and to elucidate whether tRF-3017b promotes tumor progression by modulating tumor cell proliferation, cytotoxic T lymphocyte (CTL) resistance ...
Xiaowu Liu   +6 more
doaj   +2 more sources

Integration of 12-h time-restricted feeding with exercise training potentiates weight loss and attenuates MASLD in diet-induced obese mice [PDF]

open access: yesScientific Reports
Metabolic dysfunction-associated steatotic liver disease (MASLD) is the most prevalent liver disease worldwide, particularly among individuals with overweight and obesity.
Guilherme Correia Ferri Antonio   +13 more
doaj   +2 more sources

Empagliflozin and intermittent fasting as a strategy to mitigate anthracycline-induced cardiotoxicity [PDF]

open access: yesScientific Reports
Empagliflozin (EMPA) has shown cardioprotective potential by enhancing myocardial energy availability, a mechanism also observed with intermittent fasting strategies, such as time-restricted feeding (TRF).
Juliano Moreira Reis Filho   +7 more
doaj   +2 more sources

Serum extracellular vesicles 3’tRF-ThrCGTand 3’tRF-mtlleGAT combined with tumor markers can serve as minimally invasive diagnostic predictors for colorectal cancer

open access: yesFrontiers in Oncology
BackgroundColorectal cancer (CRC) is a leading cause of morbidity and mortality, and timely diagnosis and intervention are crucial for cancer patients. Transfer RNA-derived fragments (tRFs) play a noncoding regulatory role in organisms.
Jiefei Peng   +9 more
exaly   +3 more sources

TOURIST GUIDES, COVID 19 AND SURVIVAL MECHANISMS IN SOUTH AFRICA [PDF]

open access: yesGeo Journal of Tourism and Geosites, 2021
The main aim of this research was to investigate the survival mechanisms employed by tourist guides in the context of the Covid 19 Pandemic. A mixed method research design was adopted, using in-depth interviews with key tourism informants and surveys ...
Fisokuhle MBATHA   +2 more
doaj   +1 more source

Pathogenic potential of Metarhizium anisopliae and Lecanicillium longisporum on tea mosquito bug, Helopeltis theivora Waterhouse (Hemiptera: Miridae)

open access: yesJournal of Basic and Applied Zoology, 2022
Background The study was focused on identifying the pathogenic potential of native entomopathogenic fungi (EPF) viz., Metarhizium anisopliae (Metsch.) and Lecanicillium longisporum (Zimm.) against adult tea mosquito bug (TMB), Helopeltis theivora ...
Nagaraj Santhana Bharathi   +4 more
doaj   +1 more source

Plasma exosomal tRNA‐derived fragments as diagnostic biomarkers in non-small cell lung cancer

open access: yesFrontiers in Oncology, 2022
BackgroundtRNA derived small RNAs (tRFs) have recently received extensive attention; however, the effects of tRFs in exosome as biomarkers has been less studied.
Baibing Zheng   +10 more
doaj   +1 more source

Effects of time-restricted feeding and walking exercise on the physical health of female college students with hidden obesity: a randomized trial

open access: yesFrontiers in Public Health, 2023
PurposeTime-restricted feeding (TRF) is an emerging dietary pattern with many potential effects. This study focused on the effects of TRF and walking on the physical health of female college students with hidden obesity.MethodsA total of 77 female ...
Haitao Liu   +5 more
doaj   +1 more source

The tRNA-derived fragment 5026a inhibits the proliferation of gastric cancer cells by regulating the PTEN/PI3K/AKT signaling pathway

open access: yesStem Cell Research & Therapy, 2021
Background Recently, tRNA-derived fragments (tRFs) have been shown to serve important biological functions. However, the role of tRFs in gastric cancer has not been fully elucidated.
Linwen Zhu   +8 more
doaj   +1 more source

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