Results 11 to 20 of about 20,759 (251)
Frontiers in Oncology, 2021 tRNA derivatives have been identified as a new kind of potential biomarker for cancer. Previous studies have identified that there were 30 differentially expressed tRNAs derivatives in breast cancer tissue with the high-throughput sequencing technique ...
Dongping Mo +5 more
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Frontiers in Cell and Developmental Biology, 2021 Ultraviolet (UV) radiation is a major environmental factor contributing skin damage. As UV exposure is inevitable, it is necessary to pay attention to the underlying molecular mechanisms of UV-induced skin damage to develop effective therapies.
Yuan Fang +17 more
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mt tRFs, New Players in MELAS Disease [PDF]
Frontiers in Physiology, 2022 MELAS (mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes) is an OXPHOS disease mostly caused by the m.3243A>G mutation in the mitochondrial tRNALeu(UUR) gene. Recently, we have shown that the mutation significantly changes the expression pattern of several mitochondrial tRNA-derived small RNAs (mt tsRNAs or mt tRFs) in a
Salvador Meseguer, Mari-Paz Rubio
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Telomere Restriction Fragment (TRF) Analysis [PDF]
BIO-PROTOCOL, 2015 While telomerase is expressed in ~90% of primary human tumors, most somatic tissue cells except transiently proliferating stem-like cells do not have detectable telomerase activity (Shay and Wright, 1996; Shay and Wright, 2001). Telomeres progressively shorten with each cell division in normal cells, including proliferating stem-like cells, due to the ...
ilgen Mender, Jerry Shay
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Laryngoscope Investigative Otolaryngology, 2022 Objective Time restricted feeding (TRF), which is an intermittent fasting protocol, has been reported to decrease the toxicity and mortality rate associated with systemic gentamicin (GM) administration.
Ying Gao +4 more
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Adjacency and Area Explain Species Bioregional Shifts in Neotropical Palms
Frontiers in Plant Science, 2019 Environmental and geographical variables are known drivers of community assembly, however their influence on phylogenetic structure and phylogenetic beta diversity of lineages within different bioregions is not well-understood. Using Neotropical palms as
Cintia G. Freitas +5 more
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Energy Conversion and Management: X, 2023 Butanol has a high potential as a renewable substitution for gasoline in spark-ignition direct-injection (SIDI) engines. Different butanol isomers showed various flame characteristics that are strongly related to their molecular structure. However, there
Weixuan Zhang +5 more
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Does School Functioning Matter in Patients of Child and Adolescent Mental Health Services?
Scandinavian Journal of Child and Adolescent Psychiatry and Psychology, 2012 Objective: General population studies have demonstrated that good school functioning protects children and adolescents against mental health problems. However, no such studies of clinical populations have been conducted.
Stødle Einar S., Jozefiak Thomas
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Journal of Translational Medicine, 2023 Background Myopia has emerged as a major public health concern globally, which is tightly associated with scleral extracellular matrix (ECM) remodeling and choroidal vasculopathy. Choroidal vasculopathy has gradually been recognized as a critical trigger
Chang Liu +7 more
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tRNA-derived fragment tRF-1001: A novel anti-angiogenic factor in pathological ocular angiogenesis
Molecular Therapy: Nucleic Acids, 2022 Transfer RNA-derived fragments (tRFs) are a novel class of non-coding RNA transcripts and play important roles in several physiological/pathological processes. However, the role of tRFs in ocular angiogenesis remains elusive.
Qin Jiang +6 more
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