Results 211 to 220 of about 159,938 (238)
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Transfer RNA Fragments, from Structure to Function
RNA Technologies, 2023Serafima Dubnov, Hermona Soreq
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Biochimica Et Biophysica Acta - Gene Regulatory Mechanisms, 2018 Ribosome-associated noncoding (ranc) RNAs are a novel class of short regulatory RNAs with functions and origins that have not been well studied. In this present study, we functionally characterized the molecular activity of Saccharomyces cerevisiae transfer RNA (tRNA)-derived fragments (tRFs) during protein biosynthesis.
Anna Maria Mleczko +1 more
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Journal of Computational Biology, 2020
To provide systematic insight into the composition and expression of transfer RNA (tRNA) derivatives transcriptome in colorectal cancer (CRC). tRNA derivatives expression profiles in three pairs of CRC and adjacent normal colon tissues were performed by tRNA-derived small RNA fragments (tRFs) and tRNA halves (tiRNA) sequencing, and microarray data of ...
Waleed Ghareeb, Pan Chi
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To provide systematic insight into the composition and expression of transfer RNA (tRNA) derivatives transcriptome in colorectal cancer (CRC). tRNA derivatives expression profiles in three pairs of CRC and adjacent normal colon tissues were performed by tRNA-derived small RNA fragments (tRFs) and tRNA halves (tiRNA) sequencing, and microarray data of ...
Waleed Ghareeb, Pan Chi
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Infrared Spectrum of an Anticodon Fragment of a Transfer RNA
Nature, 1969WE have observed the infrared spectrum of a fragment of a transfer RNA (tRNA) in aqueous solution and obtained evidence for the existence of the hydrogen-bonded base pairs.
K, Morikawa +4 more
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1969
Abstract 1. Limited digestion of Escherichia coli tRNAfMet by ribonuclease T1 resulted mainly in a split at -G-D(dihydrouridine)-sequence in the D loop of the tRNA. The resulting 5′- and 3′-half molecules restored the methionine-acceptor activity and the transformylation ability only when mixed. No activities were recovered with either half alone. It
T, Seno, M, Kobayashi, S, Nishimura
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Abstract 1. Limited digestion of Escherichia coli tRNAfMet by ribonuclease T1 resulted mainly in a split at -G-D(dihydrouridine)-sequence in the D loop of the tRNA. The resulting 5′- and 3′-half molecules restored the methionine-acceptor activity and the transformylation ability only when mixed. No activities were recovered with either half alone. It
T, Seno, M, Kobayashi, S, Nishimura
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International Journal of Rheumatic Diseases, 2018
AbstractAimOsteoporosis is one of the common orthopedic diseases featured in low bone mineral density. Exosomes have been proven to be potential markers for many diseases and health problems. The roles of messenger RNAs and microRNAs in osteoporosis have been comprehensively studied; however, little research has focused on the function of plasma ...
Xiaodong Liu
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AbstractAimOsteoporosis is one of the common orthopedic diseases featured in low bone mineral density. Exosomes have been proven to be potential markers for many diseases and health problems. The roles of messenger RNAs and microRNAs in osteoporosis have been comprehensively studied; however, little research has focused on the function of plasma ...
Xiaodong Liu
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Biochimica et Biophysica Acta (BBA) - Nucleic Acids and Protein Synthesis, 1972
Abstract Disc electrophoretic methods for the separation of tRNAs, tRNA fragments and oligonucleotides on the analytical and preparative scale were modified and improved. In the analytical separations the components were quantitatively determined. Calibration curves relating mobility to chain length permitted the assignment of chain length to unknown
P, Philippsen, G, Zachau
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Abstract Disc electrophoretic methods for the separation of tRNAs, tRNA fragments and oligonucleotides on the analytical and preparative scale were modified and improved. In the analytical separations the components were quantitatively determined. Calibration curves relating mobility to chain length permitted the assignment of chain length to unknown
P, Philippsen, G, Zachau
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Discovery and function of transfer
Until recently, transfer RNAs (tRNAs) were thought to function in protein translation only. However, recent findings demonstrate that both pre‐ and mature tRNAs can undergo endonucleolytic cleavage by different ribonucleases originating different types of small non‐coding RNAs, known as tRNA‐derived fragments (tRFs).
Soares, Ana Raquel, Santos, Manuel
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Genome-Wide Repertoire of Transfer RNA-Derived Fragments in a Mouse Model of Age-Related Cataract
Current Eye Research, 2022To investigate the roles of tRNA-derived small RNAs (tsRNAs) containing transfer RNA-derived fragments (tRFs) and tRNA halves in age-related cataracts (ARCs).Lens capsule tissue from Emory mice at 3 months and 8 months of age were dissected for integrated tsRNA and gene transcriptome sequencing.
Guowei, Zhang +6 more
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Profile analysis reveals transfer RNA fragments involved in mesangial cells proliferation
Biochemical and Biophysical Research Communications, 2019Mesangial cell (MCs) proliferation is an essential component of glomerulonephritis. To find some bio-markers of mesangial cell proliferation, we investigate the relationship between transfer RNA fragments (tRFs) and proliferating mesangial cells. The model of proliferating mesangial cells was built by using transforming growth factor-1(TGF-β1) treated ...
Xiaoyu, Lu +5 more
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