Clinical testing strategies for diagnosing male factor infertility are limited. A deeper analysis of spermatozoa-derived factors could potentially diagnose some cases of ‘unexplained infertility’.
Matthew Hamilton +4 more
doaj +1 more source
Biogenesis and Function of Transfer RNA-Related Fragments (tRFs).
Pankaj Kumar, Canan Kuscu, Anindya Dutta
semanticscholar +3 more sources
Characterisation of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata. [PDF]
The green bottle fly maggot, Lucilia sericata, is a species with importance in medicine, agriculture and forensics. Improved understanding of this species' biology is of great potential benefit to many research communities.
Cherie Blenkiron +6 more
doaj +1 more source
An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms
Small RNA sequencing (sRNA-Seq) approaches unveiled sequences derived from longer non-coding RNAs, such as transfer RNA (tRNA) and ribosomal RNA (rRNA) fragments, known as tRFs and rRFs, respectively.
Marine Lambert +6 more
doaj +1 more source
tRFtarget 2.0: expanding the targetome landscape of transfer RNA-derived fragments
tRFtarget 1.0 (http://trftarget.net/) is a platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments (tRFs) and target genes (or transcripts) across multiple organisms.
Ningshan Li +4 more
semanticscholar +1 more source
Transfer RNA-derived fragments: Origins, processing, and functions [PDF]
Deep sequencing approaches have revealed multiple types of small RNAs with known and unknown functions. In this review we focus on a recently identified group of small RNAs that are derived from transfer RNAs (tRNAs), tRNA fragments (tRFs). We review the
Hutvagner, G, Sobala, A
core +1 more source
Transfer RNA-derived fragments as novel biomarkers of the onset and progression of gastric cancer
Gastric cancer (GC) is a particularly malignant disease; thus, early diagnosis and treatment are especially important. Transfer RNA-derived small RNAs (tsRNAs) have been implicated in the onset and progression of various cancers.
Yaoyao Xie +4 more
semanticscholar +1 more source
MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data. [PDF]
Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly facilitated the study of tRFs.
Loher, Phillipe +2 more
core +2 more sources
Sequence organization of feline leukemis virus DNA in infected cells [PDF]
A restriction site map has been deduced of unintegrated and integrated FeLV viral DNA found in human RD cells after experimental infection with the Gardner-Arnstein strain of FeLV.
Casey, James W. +3 more
core +1 more source
Widespread mitovirus sequences in plant genomes [PDF]
The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes.
Jeremy A. Bruenn +2 more
doaj +2 more sources

