Results 31 to 40 of about 305,705 (319)

Transfer RNA-derived Small RNAs: Degradation Fragments or Novel Regulatory Molecules?* [PDF]

PROGRESS IN BIOCHEMISTRY AND BIOPHYSICS, 2011
Xin Chen, En‐Duo Wang
openalex   +2 more sources

Transfer RNA-derived fragment tRF-28-P4R8YP9LOND5 as a novel serum biomarker for gastric cancer: diagnostic efficacy and clinicopathological correlations. [PDF]

Transl Cancer Res
Gu F, Yuan Y, Cong H, Chen X, Wang W, Zhang J, Wu LP, Xuan SH.   +7 more
europepmc   +2 more sources

The Development of Methods for the Production of New Molecular Vaccines and Appropriate RNA Fragments to Counteract Unwanted Genes: A Pilot Study

Vaccines, 2023
The potential of viruses as appropriate vectors for the development of new therapeutic strategies, as well as for the design of molecular (DNA, RNA, and/or protein) vaccines via substitution of nucleotide sequences, has been proven.
Iskra Sainova, Vera Kolyovska, Iliana Ilieva, Tzvetanka Markova, Dimitrina Dimitrova-Dikanarova, Radka Hadjiolova   +5 more
doaj   +1 more source

Heat injury-induced tRNA fragment tRF-Ile-AAT-1 inhibits proliferation and invasion of bladder urothelial cancer cells

Di-san junyi daxue xuebao, 2021
Objective To investigate the effect of tRNA fragment differentially expressed between high and low malignant bladder urothelial carcinoma (BUC) cells induced by heat injury on the proliferation and invasion of BUC cells.
JIANG Li, ZHANG Junyong, TAN Peng, GOU Yang, HU Zhiya, LIN Yanjun, JIANG Qing   +6 more
doaj   +1 more source

Secretion of Mutant DNA and mRNA by the Exosomes of Breast Cancer Cells

Molecules, 2021
Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was to study the tumour exosomes’ ability to accumulate
Olga E. Andreeva, Yuri Y. Shchegolev, Alexander M. Scherbakov, Ekaterina I. Mikhaevich, Danila V. Sorokin, Margarita V. Gudkova, Irina V. Bure, Ekaterina B. Kuznetsova, Dmitry S. Mikhaylenko, Marina V. Nemtsova, Dmitry V. Bagrov, Mikhail A. Krasil’nikov   +11 more
doaj   +1 more source

Assessing spermatozoal small ribonucleic acids and their relationship to blastocyst development in idiopathic infertile males

Scientific Reports, 2022
Clinical testing strategies for diagnosing male factor infertility are limited. A deeper analysis of spermatozoa-derived factors could potentially diagnose some cases of ‘unexplained infertility’.
Matthew Hamilton, Stewart Russell, Karen Menezes, Sergey I. Moskovtsev, Clifford Librach   +4 more
doaj   +1 more source

Characterisation of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata. [PDF]

PLoS ONE, 2015
The green bottle fly maggot, Lucilia sericata, is a species with importance in medicine, agriculture and forensics. Improved understanding of this species' biology is of great potential benefit to many research communities.
Cherie Blenkiron, Peter Tsai, Lisa A Brown, Vernon Tintinger, Kathryn J Askelund, John A Windsor, Anthony R Phillips   +6 more
doaj   +1 more source

An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms

Non-Coding RNA, 2022
Small RNA sequencing (sRNA-Seq) approaches unveiled sequences derived from longer non-coding RNAs, such as transfer RNA (tRNA) and ribosomal RNA (rRNA) fragments, known as tRFs and rRFs, respectively.
Marine Lambert, Sara Guellal, Jeffrey Ho, Abderrahim Benmoussa, Benoit Laffont, Richard Bélanger, Patrick Provost   +6 more
doaj   +1 more source

MINTmap: fast and exhaustive profiling of nuclear and mitochondrial tRNA fragments from short RNA-seq data. [PDF]

, 2017
Transfer RNA fragments (tRFs) are an established class of constitutive regulatory molecules that arise from precursor and mature tRNAs. RNA deep sequencing (RNA-seq) has greatly facilitated the study of tRFs.
Loher, Phillipe, Rigoutsos, Isidore, Telonis, Aristeidis G.   +2 more
core   +2 more sources

tRFtarget 2.0: expanding the targetome landscape of transfer RNA-derived fragments

Nucleic Acids Research, 2023
Abstract tRFtarget 1.0 (http://trftarget.net/) is a platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments (tRFs) and target genes (or transcripts) across multiple organisms.
Ningshan Li, Siqiong Yao, Guangjun Yu, Lingeng Lu, Zuoheng Wang   +4 more
openaire   +2 more sources