Results 31 to 40 of about 155,620 (276)

Secretion of Mutant DNA and mRNA by the Exosomes of Breast Cancer Cells

open access: yesMolecules, 2021
Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was to study the tumour exosomes’ ability to accumulate
Olga E. Andreeva   +11 more
doaj   +1 more source

Assessing spermatozoal small ribonucleic acids and their relationship to blastocyst development in idiopathic infertile males

open access: yesScientific Reports, 2022
Clinical testing strategies for diagnosing male factor infertility are limited. A deeper analysis of spermatozoa-derived factors could potentially diagnose some cases of ‘unexplained infertility’.
Matthew Hamilton   +4 more
doaj   +1 more source

Characterisation of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata. [PDF]

open access: yesPLoS ONE, 2015
The green bottle fly maggot, Lucilia sericata, is a species with importance in medicine, agriculture and forensics. Improved understanding of this species' biology is of great potential benefit to many research communities.
Cherie Blenkiron   +6 more
doaj   +1 more source

An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms

open access: yesNon-Coding RNA, 2022
Small RNA sequencing (sRNA-Seq) approaches unveiled sequences derived from longer non-coding RNAs, such as transfer RNA (tRNA) and ribosomal RNA (rRNA) fragments, known as tRFs and rRFs, respectively.
Marine Lambert   +6 more
doaj   +1 more source

tRFtarget 2.0: expanding the targetome landscape of transfer RNA-derived fragments

open access: yesNucleic Acids Research, 2023
Abstract tRFtarget 1.0 (http://trftarget.net/) is a platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments (tRFs) and target genes (or transcripts) across multiple organisms.
Ningshan Li   +4 more
openaire   +2 more sources

Hybridization of denatured RNA and small DNA fragments transferred to nitrocellulose. [PDF]

open access: greenProceedings of the National Academy of Sciences, 1980
A simple and rapid method for transferring RNA from agarose gels to nitrocellulose paper for blot hybridization has been developed. Poly(A)+ and ribosomal RNAs transfer efficiently to nitrocellulose paper in high salt (3 M NaCl/0.3 M trisodium citrate) after denaturation with glyoxal and 50% (vol/vol) dimethyl sulfoxide.
Patricia S. Thomas
openalex   +4 more sources

Widespread mitovirus sequences in plant genomes [PDF]

open access: yesPeerJ, 2015
The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes.
Jeremy A. Bruenn   +2 more
doaj   +2 more sources

Small Non-coding RNA Expression Following Respiratory Syncytial Virus or Measles Virus Infection of Neuronal Cells

open access: yesFrontiers in Microbiology, 2021
Respiratory syncytial virus (RSV) or measles virus (MeV) infection modifies host responses through small non-coding RNA (sncRNA) expression. We show that RSV or MeV infection of neuronal cells induces sncRNAs including various microRNAs and transfer RNA ...
Abhijeet A. Bakre   +5 more
doaj   +1 more source

Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes.

open access: yesPLoS Computational Biology, 2019
The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polymerase ribozyme is divided into fragments short enough to be replicable by ...
Atsushi Kamimura   +3 more
doaj   +1 more source

Recent development of urinary biomarkers for bladder cancer diagnosis and monitoring

open access: yesClinical and Translational Discovery, 2023
Urine‐based liquid biopsy has emerged as a non‐invasive and effective tool for early screening and diagnosis of bladder cancer. This review provides a comprehensive overview of the current urine‐based biomarkers and methods for the detection and ...
Yuchen Zeng   +11 more
doaj   +1 more source

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