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Editorial: The genome’s rising star: Transfer RNA-derived small fragments
Wei Yan
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Plant transfer RNA‐derived fragments: Biogenesis and functions [PDF]
AbstractProcessing of mature transfer RNAs (tRNAs) produces complex populations of tRNA‐derived fragments (tRFs). Emerging evidence shows that tRFs have important functions in bacteria, animals, and plants. Here, we review recent advances in understanding plant tRFs, focusing on their biological and cellular functions, such as regulating stress ...
Xuan Ma, Chunyan Liu, Xiaofeng Cao
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tRFtarget: a database for transfer RNA-derived fragment targets [PDF]
AbstractTransfer RNA-derived fragments (tRFs) are a new class of small non-coding RNAs and play important roles in biological and physiological processes. Prediction of tRF target genes and binding sites is crucial in understanding the biological functions of tRFs in the molecular mechanisms of human diseases.
Ningshan Li +3 more
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Objective To investigate the effect of tRNA fragment differentially expressed between high and low malignant bladder urothelial carcinoma (BUC) cells induced by heat injury on the proliferation and invasion of BUC cells.
JIANG Li +6 more
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The potential of viruses as appropriate vectors for the development of new therapeutic strategies, as well as for the design of molecular (DNA, RNA, and/or protein) vaccines via substitution of nucleotide sequences, has been proven.
Iskra Sainova +5 more
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ASSOCIATION BETWEEN TRANSFER RNA-DERIVED FRAGMENTS AND VARICOCELE
Öz bulunamadı.
Mahmutoglu, Asli Metin +4 more
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Transfer RNA‐derived fragments: origins, processing, and functions [PDF]
AbstractDeep sequencing approaches have revealed multiple types of small RNAs with known and unknown functions. In this review we focus on a recently identified group of small RNAs that are derived from transfer RNAs (tRNAs), tRNA fragments (tRFs). We review the mechanism of their processing and their functions in mammalian cells, and highlight points ...
Andrew, Sobala, Gyorgy, Hutvagner
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Secretion of Mutant DNA and mRNA by the Exosomes of Breast Cancer Cells
Exosomes are the small vesicles that are secreted by different types of normal and tumour cells and can incorporate and transfer their cargo to the recipient cells. The main goal of the present work was to study the tumour exosomes’ ability to accumulate
Olga E. Andreeva +11 more
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PtRFdb: a database for plant transfer RNA-derived fragments [PDF]
Transfer RNA-derived fragments (tRFs) represent a novel class of small RNAs (sRNAs) generated through endonucleolytic cleavage of both mature and precursor transfer RNAs (tRNAs). These 14-28 nt length tRFs that have been extensively studied in animal kingdom are to be explored in plants. In this study, we introduce a database of plant tRFs named PtRFdb
Nikita Gupta +3 more
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Characterisation of the small RNAs in the biomedically important green-bottle blowfly Lucilia sericata. [PDF]
The green bottle fly maggot, Lucilia sericata, is a species with importance in medicine, agriculture and forensics. Improved understanding of this species' biology is of great potential benefit to many research communities.
Cherie Blenkiron +6 more
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