Results 31 to 40 of about 168,857 (234)
Transfer- or ‘transmission’-RNA fragments? The roles of tsRNAs in the reproductive system
Molecular Human Reproduction, 2021 ABSTRACTTransfer-RNAs (tRNAs) help ribosomes decode mRNAs and synthesize proteins; however, tRNA fragments produced under certain conditions, known as tRNA-derived small RNAs (tsRNAs), have been found to play important roles in pathophysiological processes. In the reproductive system, tsRNAs are abundant in gametes and embryos and at the maternal–fetal
Hui-Min Li +4 more
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Scientific Reports, 2022 Clinical testing strategies for diagnosing male factor infertility are limited. A deeper analysis of spermatozoa-derived factors could potentially diagnose some cases of ‘unexplained infertility’.
Matthew Hamilton +4 more
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An Expanded Landscape of Unusually Short RNAs in 11 Samples from Six Eukaryotic Organisms
Non-Coding RNA, 2022 Small RNA sequencing (sRNA-Seq) approaches unveiled sequences derived from longer non-coding RNAs, such as transfer RNA (tRNA) and ribosomal RNA (rRNA) fragments, known as tRFs and rRFs, respectively.
Marine Lambert +6 more
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Transfer
New Phytologist, 2023 SummaryAccording to current textbooks, the principal task of transfer and ribosomal RNAs (tRNAs and rRNAs, respectively) is synthesizing proteins. During the last decade, additional cellular roles for precisely processed tRNA and rRNAs fragments have become evident in all kingdoms of life. These RNA fragments were originally overlooked in transcriptome
Panstruga, Ralph, Spanu, Pietro
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The abundance of a transfer RNA-derived RNA fragment small RNA subpopulation is enriched in cauda spermatozoa [PDF]
ExRNA, 2020 AbstractThe small RNA (sRNA) landscape of mammalian spermatozoa is considerably altered as these gametic cells migrate through the segment specific microenvironments of the epididymis. More specifically, the microRNA (miRNA) species of sRNA dominates the sRNA landscape of spermatozoa of the proximal caput segment of the epididymis.
Simone J. Stanger +6 more
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Scientific Reports, 2021 Small RNAs that originate from transfer RNA (tRNA) species, tRNA-derived fragments (tRFs), play diverse biological functions but little is known for their association with aging.
GiWon Shin +5 more
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tRFtarget 2.0: expanding the targetome landscape of transfer RNA-derived fragments
Nucleic Acids Research, 2023 Abstract tRFtarget 1.0 (http://trftarget.net/) is a platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments (tRFs) and target genes (or transcripts) across multiple organisms.
Ningshan Li +4 more
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Widespread mitovirus sequences in plant genomes [PDF]
PeerJ, 2015 The exploration of the evolution of RNA viruses has been aided recently by the discovery of copies of fragments or complete genomes of non-retroviral RNA viruses (Non-retroviral Endogenous RNA Viral Elements, or NERVEs) in many eukaryotic nuclear genomes.
Jeremy A. Bruenn +2 more
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Frontiers in Microbiology, 2021 Respiratory syncytial virus (RSV) or measles virus (MeV) infection modifies host responses through small non-coding RNA (sncRNA) expression. We show that RSV or MeV infection of neuronal cells induces sncRNAs including various microRNAs and transfer RNA ...
Abhijeet A. Bakre +5 more
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Horizontal transfer between loose compartments stabilizes replication of fragmented ribozymes.
PLoS Computational Biology, 2019 The emergence of replicases that can replicate themselves is a central issue in the origin of life. Recent experiments suggest that such replicases can be realized if an RNA polymerase ribozyme is divided into fragments short enough to be replicable by ...
Atsushi Kamimura +3 more
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