Results 151 to 160 of about 99,404 (289)

Redox‐Responsive Polymeric Nanocapsules for Enhanced Tumor‐Targeted Delivery of Antimicrobial Peptides

open access: yesAdvanced Science, EarlyView.
This study presents a modular redox‐responsive nanocapsule platform that enables enhanced tumor‐targeted delivery of antimicrobial peptides. Using melittin as an example, the system achieves controlled activation within the tumor microenvironment, improving intratumoral accumulation while minimizing systemic toxicity.
Lin Tang   +9 more
wiley   +1 more source

A Genomic Catalog of Migratory Microbiomes from Wild Birds across China's Habitats

open access: yesAdvanced Science, EarlyView.
ABSTRACT Migratory birds play an important role in the spread of antimicrobial resistance (AMR); however, gaps in surveillance data from vital regions along migratory flyways across China limit the detection of emergent threats. Here, we assembled 340 metagenomes from 52 bird species covering 11 provincial administrative districts in China, presenting ...
Yanan Wang   +13 more
wiley   +1 more source

Post‐Translational Regulation of CD8+ T Cell Fate and Dysfunction in Tumor Immunity

open access: yesAdvanced Science, EarlyView.
This review delineates how post‐translational modifications (PTMs) function as a central regulatory interface governing CD8+ T cell activation, differentiation, persistence, and exhaustion in antitumor immunity. By integrating antigenic, metabolic, and microenvironmental cues, diverse PTM programs coordinate transcriptional and chromatin states that ...
Zihao Zhou   +8 more
wiley   +1 more source

Gamma-glutamyl cycle in plants: a bridge connecting the environment to the plant cell? [PDF]

open access: yes, 2015
Ganesh K., Agrawal   +3 more
core   +1 more source

Ferroptosis Induction by Fenbendazole Combined With Photothermal Therapy Triggers Dual‐Immunotherapy Against Bladder Cancer

open access: yesAdvanced Science, EarlyView.
The novel intravesical delivery system exhibits GSH‐responsive drug release, enabling a synergistic therapeutic strategy that combines ferroptosis, ICD and PTT. ABSTRACT Ferroptosis, a newly recognized form of regulated cell death, has emerged as a promising strategy in cancer therapy.
Xiaojian Xu   +15 more
wiley   +1 more source

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