Results 61 to 70 of about 99,404 (289)

GalNAc-Transferases in Cancer

open access: yesBiomedicines
Background/Objectives: The polypeptide N-acetylgalactosaminyltransferase (GALNT) family initiates mucin-type O-glycosylation, a post-translational modification that plays a pivotal role in cellular signaling, adhesion, and immune evasion.
Shruthi C. Iyer   +2 more
doaj   +1 more source

Regulation of Signal Transduction by Glutathione Transferases

open access: yesInternational Journal of Hepatology, 2012
Glutathione transferases (GST) are essentially known as enzymes that catalyse the conjugation of glutathione to various electrophilic compounds such as chemical carcinogens, environmental pollutants, and antitumor agents.
Julie Pajaud   +4 more
doaj   +1 more source

Two functionally distinctive phosphopantetheinyl transferases from amoeba Dictyostelium discoideum. [PDF]

open access: yesPLoS ONE, 2011
The life cycle of Dictyostelium discoideum is proposed to be regulated by expression of small metabolites. Genome sequencing studies have revealed a remarkable array of genes homologous to polyketide synthases (PKSs) that are known to synthesize ...
Divya R Nair   +5 more
doaj   +1 more source

AMPylation profiling during neuronal differentiation reveals extensive variation on lysosomal proteins

open access: yesiScience, 2021
Summary: Protein AMPylation is a posttranslational modification with an emerging role in neurodevelopment. In metazoans two highly conserved protein AMP-transferases together with a diverse group of AMPylated proteins have been identified using chemical ...
Tobias Becker   +8 more
doaj   +1 more source

Role of ethylene on various ripening pathways and on the development of sensory quality of Charentais cantaloupe melons [PDF]

open access: yes, 2002
Charentais melons (Cucumis melo L., var cantalupensis Naud.) in which ethylene biosynthesis has been suppressed by an antisense ACC oxidase gene have been used to better understand the role of ethylene in the regulation of the ripening process of ...
Ambid, Christian   +9 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina   +11 more
wiley   +1 more source

Characterization of Genes Involved in the Formation of Aroma Volatiles in "Charentais" Melon Fruit [PDF]

open access: yes, 2004
Volatiles esters impart distinct characteristics to the fruit quality. "Charentais" cantaloupe melon (Cucumis melo "cantalupensis") is characterized by abundant sweetness and aromatic flavour.
El-Sharkawy, Islam   +4 more
core   +1 more source

MagPiezo: A Magnetogenetic Platform for Remote Activation of Endogenous Piezo1 Channels in Endothelial Cells

open access: yesAdvanced Functional Materials, EarlyView.
MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández   +7 more
wiley   +1 more source

Structure and functions of glutathione transferases

open access: yesThe Ukrainian Biochemical Journal, 2014
Data about classification, nomenclature, structure, substrate specificity and role of many glutathione transferase’s isoenzymes in cell functions have been summarised. The enzyme has been discovered more than 50 years ago.
O. M. Fedets
doaj   +1 more source

Glutathione S-transferases in pediatric cancer

open access: yesFrontiers in Oncology, 2011
The glutathione S-transferases (GSTs) are a family of ubiquitously-expressed polymorphic enzymes important for detoxifying endogenous and exogenous compounds.
Wen eLuo   +3 more
doaj   +1 more source

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