Results 81 to 90 of about 212,981 (331)

The chromatin remodelling complex B-WICH changes the chromatin structure and recruits histone acetyl-transferases to active rRNA genes.

PLoS ONE, 2011
The chromatin remodelling complex B-WICH, which comprises the William syndrome transcription factor (WSTF), SNF2h, and nuclear myosin 1 (NM1), is involved in regulating rDNA transcription, and SiRNA silencing of WSTF leads to a reduced level of 45S pre ...
Anna Vintermist, Stefanie Böhm, Fatemeh Sadeghifar, Emilie Louvet, Anethe Mansén, Pergiorgio Percipalle, Ann-Kristin Ostlund Farrants   +6 more
doaj   +1 more source

Nomenclature for mammalian soluble glutathione transferases

, 2005
The nomenclature for human soluble glutathione transferases (GSTs) is extended to include new members of the GST superfamily that have been discovered, sequenced, and shown to be expressed.
Pearson, William R, Listowsky, Irving, William R. Pearson, Philip G. Board, Board, Philip, John D. Hayes, Board, Philip G., Hayes, John D, Bengt Mannervik, Pearson, William R., Hayes, John D., Irving Listowsky, Mannervik, Bengt   +12 more
core   +1 more source

Copper‐Driven Epithelial Barrier Disruption: A Novel Mechanism of COPD Acute Exacerbations Mediated by the TNF‐α/ATP7A Axis

Advanced Science, EarlyView.
This study reveals a copper‐driven mechanism of COPD acute exacerbations mediated by the TNF‐α/ATP7A axis. TNF‐α suppresses the copper transporter ATP7A via competitive NF‐κB/CREB1/CBP signaling, resulting in intracellular copper accumulation, mitochondrial oxidative stress, and epithelial barrier disruption.
Xinru Xiao, Yongzhe Hao, Ziqi Ding, Zhipeng Wang, Yujia Shi, Yanhua Huang, Chunjian Qi, Qian Zhang   +7 more
wiley   +1 more source

The Activities Of Herbicide Safeners In Wheat (Triticum aestivum L) [PDF]

, 2012
Commercialised herbicide safeners (also known as protectants or antidotes) are synthetic chemicals used to enhance herbicide tolerance in cereal crops.
TAYLOR, VICTORIA,LOUISE
core  

TRAIP Mediates Alcohol‐Induced Liver Injury through Regulating β‐catenin Ubiquitin Degradation via Direct Interaction

Advanced Science, EarlyView.
This study reveals that NF‐κB1‐driven TRAIP upregulation in ALD correlates with disease severity. Mechanistically, TRAIP directly binds β‐catenin via its CC domain and promotes its K48‐linked ubiquitination and degradation, which is independent of the GSK3β/β‐TrCP pathway.
Zhan Wu, Mingjiang Liu, Lijuan Liao, Zhaohong Mo, Wenli Xu, Linfeng Mao, Yubing Chen, Qiuli Xie, Ming Yao, Shilian Chen, Stephen Tomlinson, Sebastian Mueller, Songqing He, Guandou Yuan   +13 more
wiley   +1 more source

Editorial: Discovery, biosynthesis, regulation, transport, release and engineering of plant natural products

Frontiers in Plant Science, 2022
Wei Zhou, Milen I. Georgiev, Milen I. Georgiev, Pan Liao, Pan Liao, Pan Liao, Pan Liao, Pan Liao   +7 more
doaj   +1 more source

UDP‐Glucose‐6‐Dehydrogenase Mediated O‐GlcNAcylation of Tight Junction Protein 1 Suppresses Metastasis in Renal Cell Carcinoma

Advanced Science, EarlyView.
Our research unveiled a regulatory paradigm wherein TRIM25 orchestrates the ubiquitin‐mediated degradation of UGDH. UGDH modulates the protein stability of TJP1 by regulating O‐GlcNAcylation levels, effectively impeding the metastasis of ccRCC. Our insights elevate UGDH to a pivotal biomarker and tumor suppressor, marking the first demonstration that ...
Xiaolin Chen, Yuhang Bao, Tao Liu, Jianhui Qiu, Yuanyuan Ma, Zedan Zhang, Chuandong Wang, Ruiyi Deng, Zheng Song, Tianyi He, Haode Liu, Jingcheng Zhou, Yizhou Wang, Kan Gong   +13 more
wiley   +1 more source

Genetic polymorphisms of glutathione S transferase and cervical intraepithelial neoplasia

Romanian Journal of Laboratory Medicine, 2016
Aim: The present study aim to analyze the relationship between GST M/T genotypes of glutathione S-transferases and cervical intraepithelial neoplasia.
Daniel Mureșan, Cătană Andreea, Popp Radu Anghel, Dumitraș Diana Elena, Stamatian Florin, Buzoianu Anca Dana, Rotar Ioana Cristina   +6 more
doaj   +1 more source

Hydroxycinnamoyl-coenzyme A: tetrahydroxyhexanedioate hydroxycinnamoyl transferase (HHHT) from Phaseolus vulgaris L.: phylogeny, expression pattern, kinetic parameters, and active site analysis [PDF]

PeerJ
BAHD acyl-coenzyme A (CoA) transferases comprise a large family of enzymes in plants which transfer an acyl group from a CoA thioester to hydroxyl or amine groups to form esters or amides, respectively.
Amanda Fanelli, Christina Stonoha-Arther, Michael L. Sullivan   +2 more
doaj   +2 more sources