Results 11 to 20 of about 300 (142)
Beni-Suef University Journal of Basic and Applied SciencesDue to challenges such as poor aqueous solubility and compromised oral bioavailability, delivering Vemurafenib via a topical route using a scalable and biocompatible carrier-based hydrogel.
Alam Aftab
exaly +2 more sources
Role of Surface Active Agents in Transferosome for Systemic Drug Delivery
Al Mustansiriyah Journal of Pharmaceutical SciencesThe recent utilization of transferosomes (a type of vesicular drug-carrier system) has shown promising results in enhancing the transport of drugs through the skin when administered topically.
Zainab H Mahdi
exaly +3 more sources
Review on Transferosomes and Transferosomal Gels
Journal of Pharmaceutical Research International, 2021 Transdermal drug delivery systems (TDDS), which are self-administrable and non-invasive, can improve bioavailability and patient compliance by bypassing first-pass metabolism. Vesicular-based TDDS have attracted a lot of attention in recent years because they're designed for controlled, efficient, and targeted drug delivery.
R. Santosh Kumar, P. Kranthi Kumar
openaire +2 more sources
Transferosomes: A Novel Topical Approach
Journal of Drug Delivery and Therapeutics, 2023 Transdermal drug delivery technologies have gained attention in recent years due to their advantages over conventional drug delivery systems. Transdermal drug delivery is limited because the stratum corneum functions as a barrier. Transferosomes are ultradeformable vesicles consisting of a lipid bilayer with phospholipids and an edge activator.
M. Sunitha Reddy, Shruti Rao Kodi
openaire +1 more source
Formulation and evaluation of Lamivudine transferosomal gel
Journal of Drug Delivery and Therapeutics, 2022 Aim and objective: The aim of the study was to formulate and evaluate Transferosomal gel of lamivudine. Method:Lamivudine transferosomes was prepared using thin film hydration method taking span 80, Polyoxyethylene lauryl ether in different proportion. the formulation was characterised by UV spectroscopy, FTIR, in-vitro drug release, gel evaluations.
S.M. Shahidulla, Syeda Hassan Yameen
openaire +1 more source
Formulation and Evaluation of a Transferosomal Gel of Famciclovir for Transdermal Use. [PDF]
Turk J Pharm Sci, 2023 Famciclovir, the drug of choice for cold sores and recurrent genital herpes, has poor oral bioavailability and is associated with numerous side effects. The study aimed to explore the possibility of transdermal application of famciclovir through a transferosome-loaded gelling system to localize the drug at the site of application with improved ...
Bhattacharyya S +2 more
europepmc +3 more sources
Pharmaceutics, 2023 Depression is a serious mental disorder and the most prevalent cause of disability and suicide worldwide. Quercetin (QER) demonstrated antidepressant effects in rats exhibiting anxiety and depressive-like behaviors.
Mohammed H. Elkomy +10 more
doaj +1 more source
Vesicular Carriers for Follicular Drug Delivery [PDF]
Pharmaceutical SciencesThe follicular route has been explored for both topical and systemic drug delivery but its application is challenged by different limitations such as sebum flow and size-selectivity.
Mostafa Amirinejad +3 more
doaj +1 more source
Health Sciences Review, 2023 In spite of being most common, oral and parenteral drug delivery routes are associated with major biopharmaceutical hurdles. These can lead to less or no therapeutic effect due to drug precipitation as a result of first-pass metabolism as well as disease
Maitrayee Ghosh +2 more
doaj +1 more source
Microneedle Technology in Psoriasis Management: Mechanistic Insights, Technological Innovation, Clinical Progress, and Challenges. [PDF]
Adv Healthc MaterThis review explores the evolving role of microneedle systems in psoriasis management, highlighting their potential for enhanced drug delivery, diagnosis, and disease monitoring. It also discusses unmet clinical needs for psoriasis management and technical challenges, while outlining strategic directions to advance microneedle integration into routine ...
Moawad F +3 more
europepmc +2 more sources