Results 41 to 50 of about 300 (142)
Particle &Particle Systems Characterization, Volume 42, Issue 10, October 2025.This review explores improved tetracycline (TCN) delivery via polymer‐based nanocarriers to enhance solubility, stability, and targeted release. It also covers stimuli‐responsive systems, triggered by pH, enzymes, or reactive oxygen species (ROS), and co‐delivery approaches that increase therapeutic efficacy in cancer and inflammatory diseases ...
Mahsa Molaei Nasr +5 more
wiley +1 more source
DESIGN AND CHARACTERIZATION OF TRANSFEROSOMAL GEL OF REPAGLINIDE
International Research Journal of Pharmacy, 2015 The main aim of current investigation is to formulate and evaluate transferosomal gel for effective transdermal delivery of r epaglinide. Repaglinide is an oral anti hyperglycemic agent used for the treatment of non - insulin - dependent diabetes mellitu s ( NIDDM ).
Vijaya Laxmi M +2 more
openaire +1 more source
Advanced Materials Interfaces, Volume 12, Issue 18, September 22, 2025.Rheumatoid arthritis, a chronic inflammatory joint disease, faces limitations with conventional therapies. Dissolving microneedles (DMNs) enable biocompatible, high‐capacity transdermal drug delivery. However, skin elasticity challenges their strength, limiting drug release depth.
Wangrui Peng +4 more
wiley +1 more source
Iraqi Journal of Pharmaceutical SciencesThe transdermal route of drug delivery has received significant attention in pharmaceutical research due to its ability to overcome many challenges associated with oral medication administration, including the ability to bypass first-pass metabolism ...
Mohsin Hussein Abdulameer +1 more
doaj +1 more source
Development of transferosomes for topical ocular drug delivery of curcumin
European Journal of Pharmaceutics and BiopharmaceuticsTransferosomes (TFS) are ultra-deformable elastic bilayer vesicles that have previously been used to enhance gradient driven penetration through the skin. This study aimed to evaluate the potential of TFS for topical ocular drug delivery and to compare their penetration enhancing properties in different ocular tissues.Curcumin-loaded TFS were prepared ...
Geisa Nascimento Barbalho +7 more
openaire +2 more sources
Transdermal Liposomal Delivery Systems: Advantages, Applications, Challenges, and Prospects
MedComm – Biomaterials and Applications, Volume 4, Issue 3, September 2025.This review summarizes advances in liposomal transdermal systems (ethosomes, transfersomes, niosomes, pharmacosomes), focusing on their mechanisms, clinical potential in disease therapy, and future challenges to enhance translation and innovation.
Hui Xing +5 more
wiley +1 more source
Soft Nanocarriers as Antimicrobial Co‐Delivery Systems to Combat Resistant Infections
Advanced Healthcare Materials, Volume 14, Issue 21, August 19, 2025.Soft nanocarrier‐based co‐delivery systems present a versatile and promising platform for combating antimicrobial resistance (AMR) by enabling spatiotemporally controlled, pathogen‐specific drug release. Their tunable physicochemical properties allow for the co‐encapsulation of synergistic antimicrobial agents, optimization of drug ratios, and surface ...
Anamarija Nikoletic +5 more
wiley +1 more source
In Situ Gels for Nasal Delivery: Formulation, Characterization and Applications
Macromolecular Materials and Engineering, Volume 310, Issue 6, June 2025.Drug delivery through the nasal route offers many advantages, but is hampered by a number of challenges, such as the short drug retention time caused by mucociliary clearance. In situ forming gels, which undergo a sol‐to‐gel transition with specific triggers at the site of action, present real opportunities in this field.
Li Qian +2 more
wiley +1 more source
Journal of Applied Pharmaceutical ResearchBackground: This study optimizes and evaluates transferosomes containing Nebivolol Hydrochloride to enhance the drug's bioavailability and therapeutic efficacy.
P V Shelke +4 more
doaj +1 more source
The Nasal–Brain Drug Delivery Route: Mechanisms and Applications to Central Nervous System Diseases
MedComm, Volume 6, Issue 6, June 2025.Τhe BBB restricts CNS drug delivery. NBDD bypasses the BBB via olfactory/trigeminal routes, enabling CNS delivery of therapeutic (small molecules, biologics, nucleic acids) for neurodegenerative/psychiatric disorders and brain tumors using advanced NBDD delivery systems (e.g nanocarriers) to enhance targeting and bioavailability.
Yi Qiu +7 more
wiley +1 more source