Results 51 to 60 of about 300 (142)

Formulation Optimization, Physicochemical Characterization, and Biocompatibility Assessment of Curcumin‐Loaded Aquasomes

open access: yesNano Select, Volume 6, Issue 6, June 2025.
This study explores a novel approach to enhance the bioavailability and functionality of curcumin by loading it onto HAP cores coated with various disaccharides. To improve the delivery and stability of the HAP cores, they were coated with different disaccharides; lactose, maltose, sucrose, and trehalose.
Fernando Bwalya   +2 more
wiley   +1 more source

Formulation and evaluation of repurposed ketoconazole‐loaded transferosomal gel for enhanced trichogenic effects

open access: yesClinical and Translational Discovery, Volume 5, Issue 2, April 2025.
Development and characterization of a ketoconazole‐loaded transferosomal gel for enhanced trichogenic activity . Abstract This study was focused to formulate and optimize transferosomes encapsulating ketoconazole (KTZ) for its repurposed use as a hair growth promoting agent.
Madhvi Mishra   +11 more
wiley   +1 more source

Preparation and clinical evaluation of nano-transferosomes for treatment of erectile dysfunction

open access: yesDrug Design, Development and Therapy, 2015
Maha Fadel M Ali,1 Heba F Salem,2 Hany F Abdelmohsen,3 Sameh K Attia4 1Pharmaceutical Technology Unit, Medical Applications of Lasers Department, National Institute of Laser Enhanced Science, Cairo University, Cairo, Egypt; 2Pharmaceutics and Industrial
Ali MFM   +3 more
doaj  

A State‐of‐the‐Art Appraisal of Nanomaterials in Microneedles in the Delivery of Therapeutics and Vaccines

open access: yesAdvanced NanoBiomed Research, Volume 5, Issue 3, March 2025.
Nanomaterial‐integrated microneedles revolutionize transdermal delivery, enabling targeted and controlled administration of therapeutics and vaccines. This review explores advancements in design, manufacturing, and applications, emphasizing enhanced drug stability, bioavailability, and patient adherence. Key preclinical and clinical findings as well as
Bwalya Angel Witika   +3 more
wiley   +1 more source

Overcoming the Blood–Brain Barrier: Multifunctional Nanomaterial‐Based Strategies for Targeted Drug Delivery in Neurological Disorders

open access: yesSmall Science, Volume 4, Issue 12, December 2024.
This review explores the diverse range of nanomaterials, including polymer, lipid, gold, magnetic, and carbon‐based nanostructures, capable of effectively passing the blood–brain barrier (BBB). Moreover, the structure and function of the BBB in both healthy and diseased states are discussed and the potential of nanotechnology in bypassing the BBB to ...
Callan D. McLoughlin   +4 more
wiley   +1 more source

OGG1: An emerging multifunctional therapeutic target for the treatment of diseases caused by oxidative DNA damage

open access: yesMedicinal Research Reviews, Volume 44, Issue 6, Page 2825-2848, November 2024.
Abstract Oxidative DNA damage‐related diseases, such as incurable inflammation, malignant tumors, and age‐related disorders, present significant challenges in modern medicine due to their complex molecular mechanisms and limitations in identifying effective treatment targets.
Yunxiao Zhong   +9 more
wiley   +1 more source

Progress in Lipid and Inorganic Nanocarriers for Enhanced Skin Drug Delivery

open access: yesAdvanced NanoBiomed Research, Volume 4, Issue 6, June 2024.
Nanocarriers for topical and transdermal drug delivery consist of two primary types: lipid and inorganic. The most used are lipid nanocarriers, owing to their biocompatibility and ability to encapsulate a wide range of drugs. Despite the large number of nanocarriers being investigated, only a few have been clinically approved.
Lamyaa Albakr   +6 more
wiley   +1 more source

New trends on personalized sunscreens

open access: yesPhotodermatology, Photoimmunology &Photomedicine, Volume 40, Issue 3, May 2024.
Abstract Background/Purpose Nowadays, there are emerging trends in customized and personalized photoprotection, focusing on the innovative approaches to enhance sun protection efficacy tailored to individual needs. Methods We conducted an electronic search of the following databases: MEDLINE, EMBASE, Cochrane Database of Systematic Reviews, Cochrane ...
Tamara Gracia‐Cazaña   +5 more
wiley   +1 more source

Transferosomes- Nano Vesicular Carrier for Skin Cancer

open access: yesInternational Journal of Research in Pharmaceutical Sciences, 2020
Transferosomes creating a new development in delivering a drug through skin. In oral, parenteral drug delivery system shows poor patient compliance are the major complication in clinical practice. Well, Transdermal route has obtained an appreciable interest in pharmaceutical research.
null Komathy J   +3 more
openaire   +1 more source

Statistical Optimization and Characterization of Nimodipine Transferosomes

open access: yesAl-Rafidain Journal of Medical Sciences ( ISSN 2789-3219 )
Background: Nimodipine is a vasodilator that is used for the prevention of cerebral vasospasm after subarachnoid hemorrhage. The oral and intravenous administration of the drug is associated with undesirable side effects. So, transdermal delivery using lipid-based nanovesicles, also known as transferosomes, can be thought of as an alternative ...
Samir Hasson Ramadhan   +1 more
openaire   +1 more source

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