Results 91 to 100 of about 162,073 (298)

Therapeutic MSC exosomes are derived from lipid raft microdomains in the plasma membrane

Journal of Extracellular Vesicles, 2013
Background: Mesenchymal stem cell (MSC) was previously shown to secrete lipid vesicles that when purified by high performance liquid chromatography as a population of homogenously sized particles with a hydrodynamic radius of 55–65 nm reduce infarct size
Soon Sim Tan, Yijun Yin, Tricia Lee, Ruenn Chai Lai, Ronne Wee Yeh Yeo, Bin Zhang, Andre Choo, Sai Kiang Lim   +7 more
doaj   +1 more source

Purified meningococcal transferrin-binding protein B interacts with a secondary, strain-specific, binding site in the N-terminal lobe of human transferrin [PDF]

Biochemical Journal, 1999
Neisseria meningitidis, grown in iron-limited conditions, produces two transferrin-binding proteins (TbpA and TbpB) that independently and specifically bind human serum transferrin (hTF) but not bovine serum transferrin (bTF). We have used surface plasmon resonance to characterize the interaction between individual TbpA and TbpB and a series of full ...
I C, Boulton, A R, Gorringe, B, Gorinsky, M D, Retzer, A B, Schryvers, C L, Joannou, R W, Evans   +6 more
openaire   +2 more sources

Displacement of the canonical single-stranded DNA-binding protein in the Thermoproteales

, 2011
Single-stranded DNA binding proteins (SSBs) based on the OB-fold are considered ubiquitous in nature and play a central role in many DNA transactions including replication, recombination and repair.
Kroonin, Eugene V., Naismith, Jim, McMahon, Stephen, White, Malcolm F, Sonia Paytubi, Catherine H. Botting, Graham, Shirley, Botting, Catherine Helen, James H. Naismith, Malcolm F. White, Paytubi, Sonia, Shirley Graham, Liu, Huanting, Kira S. Makarova, Makarova, Kira S., Stephen A. McMahon, Huanting Liu, Eugene V. Koonin   +17 more
core   +1 more source

TbGT8 is a bifunctional glycosyltransferase that elaborates N-linked glycans on a protein phosphatase AcP115 and a GPI-anchor modifying glycan in Trypanosoma brucei [PDF]

, 2014
The procyclic form of Trypanosoma brucei expresses procyclin surface glycoproteins with unusual glycosylphosphatidylinositol-anchor side chain structures that contain branched N-acetyllactosamine and lacto-N-biose units.
Hashida, Kazunori, Ferguson, Michael A.J., Nakanishi, Masayuki, Karasudani, Moe, Nomoto, Hiroshi, Hino, Mami, Ferguson, Michael A. J; id_orcid, Shiraishi, Takahiro   +7 more
core   +1 more source

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

Rational selection of TbpB variants yields a bivalent vaccine with broad coverage against Neisseria gonorrhoeae

npj Vaccines
Neisseria gonorrhoeae is an on-going public health problem due in part to the lack of success with efforts to develop an efficacious vaccine to prevent this sexually transmitted infection.
Jamie E. Fegan, Epshita A. Islam, David M. Curran, Dixon Ng, Natalie Y. T. Au, Elissa G. Currie, Joseph J. Zeppa, Jessica Lam, Anthony B. Schryvers, Trevor F. Moraes, Scott D. Gray-Owen   +10 more
doaj   +1 more source

Biochemical and Hematologic Monitoring and Evaluation of Elite Greek Track-and-Field Athletes

Proceedings, 2019
AIM: Monitoring biochemical and hematologic parameters in athletes at regular intervals is essential for the evaluation, protection, and improvement of their health and performance.
Anatoli Petridou, Dionyssios Chissas, Ioannis Koutsioras, Spyros Kellis, Vassilis Mougios   +4 more
doaj   +1 more source

DNA Binding in High Salt: Analysing the Salt Dependence of Replication Protein A3 from the Halophile Haloferax volcanii [PDF]

Halophilic archaea maintain intracellular salt concentrations close to saturation to survive in high-salt environments and their cellular processes have adapted to function under these conditions.
Patoli, B, Bunting, KA, Winter, JA
core   +1 more source

Turning Unpredictable Biomolecule Adsorption to Controlled Corona Formation: Focus on Carbon Nanomaterials

Advanced Materials, EarlyView.
Controlling the protein corona formation onto carbon nanomaterials (CNMs) enhances their functionalities as platforms for cancer theranostics. Here, we reviewed the effects of the intrinsic and acquired properties of CNMs on protein corona formation, the consequent biological and toxicological outcomes, and the strategies to reshape corona formation ...
Yajuan Zou, Yalei Hu, Jie Yu, Naoki Komatsu, Yuta Nishina, Alberto Bianco   +5 more
wiley   +1 more source

Annexin A2 and lamin B join membrane recycling compartments for the assembly of biomolecular condensates operating in mitotic partitioning

Frontiers in Cell and Developmental Biology
Localization of the actin-, lipid- and mRNA-binding protein Annexin A2 (AnxA2) in dividing cells revealed its presence in large spherical structures which are confined to the cell periphery and frequently co-align with astral microtubules.
Ann Kari Grindheim, Ann Kari Grindheim, Hege Dale, Josef Novák, Sudarshan Shantinath Patil, Anni Vedeler, Jaakko Saraste, Jaakko Saraste   +7 more
doaj   +1 more source