Results 11 to 20 of about 128,806 (310)

Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Transition metals are essential for metalloprotein function among all domains of life. Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins such as hemoglobin, transferrin, and lactoferrin across a variety of ...
Julie Lynn Stoudenmire   +2 more
doaj   +1 more source

Paraoxonases (PON) 1, 2, and 3 Polymorphisms and PON-1 Activities in Patients with Sickle Cell Disease

open access: yesAntioxidants, 2019
(1) Background: Oxidative stress, chronic inflammation, vasoocclusion, and free iron are all features present in sickle cell disease. Paraoxonases (PON) are a family (PON-1, PON-2, PON-3) of antioxidant enzymes with anti-inflammatory action.
Cadiele Oliana Reichert   +8 more
doaj   +1 more source

Key players in the regulation of iron homeostasis at the host-pathogen interface

open access: yesFrontiers in Immunology, 2023
Iron plays a crucial role in the biochemistry and development of nearly all living organisms. Iron starvation of pathogens during infection is a striking feature utilized by a host to quell infection.
Inam Ullah, Minglin Lang, Minglin Lang
doaj   +1 more source

Abnormal Serum Iron-Status Indicator Changes in Amyotrophic Lateral Sclerosis (ALS) Patients: A Meta-Analysis

open access: yesFrontiers in Neurology, 2020
Background: In recent years, the role of iron metabolism in amyotrophic lateral sclerosis (ALS) attracts more and more attention, and some studies have focused on the link between abnormal serum iron indicators and ALS.
Lan Wang   +4 more
doaj   +1 more source

Indices of metal proteins (transferrin, ceruloplasmin) in overweight and obese children [PDF]

open access: yesArchives of the Balkan Medical Union, 2019
Introduction. A progressive increase of obesity prevalence, both among adults and children, is observed in many countries. Today, obesity is seen as a chronic systemic inflammation with low activity. Currently, new data are available about the biological
Tamila V. SOROKMAN   +5 more
doaj   +1 more source

Clinical Utility of Fecal Immunochemical Transferrin Test in Gastrointestinal Bleeding Detection

open access: yesAnnals of Clinical Microbiology, 2018
Background: Gastrointestinal (GI) bleeding can result from various conditions, including ulcers, neoplasms and infectious enterocolitis. The aim of this study was to evaluate the utility of the fecal immunochemical transferrin test compared with the ...
Jong-Mi Lee   +7 more
doaj   +1 more source

Transferrin Functionalized Liposomes Loading Dopamine HCl: Development and Permeability Studies across an In Vitro Model of Human Blood–Brain Barrier

open access: yesNanomaterials, 2018
The transport of dopamine across the blood brain barrier represents a challenge for the management of Parkinson’s disease. The employment of central nervous system targeted ligands functionalized nanocarriers could be a valid tactic to overcome this ...
Antonio Lopalco   +5 more
doaj   +1 more source

Pre‐culture with transferrin‐Fe3+ before in vitro maturation improves the developmental competence of porcine oocytes matured in vitro

open access: yesReproductive Medicine and Biology, 2023
Purpose Since the developmental competence of oocytes cultured after in vitro maturation (IVM) is low, it is necessary to improve the IVM method for efficient offspring production.
Shingo Tonai   +5 more
doaj   +1 more source

Zinc Supplementation Combats Tuberculosis by Reverting Back to Normal Compartmentalized State of Iron and Hence Increasing Blood Hemoglobin Concentration [PDF]

open access: yesIndian Journal of Medical Biochemistry, 2023
Aim and background: To acquire iron (Fe), Mycobacterium tuberculosis (Mtb) expresses high-affinity Fe+3-specific siderophores for scavenging Fe from host insoluble and protein-bound iron-like transferrin, lactoferrin, ferritin, and hemoglobin−haptoglobin.
Dipak Kumar Chattopadhyay
doaj   +1 more source

Iron metabolism and peripheral eosinophil count do not correlate in the general population

open access: yesJournal of Biological Research, 2023
Iron is a primary component of the human body and exerts many functions, mainly concerning red cells and the immune system. In addition, there is evidence that iron-deficiency anemia is associated with allergic diseases. Type 2 inflammation characterizes
Mara De Amici   +7 more
doaj   +1 more source

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