Results 11 to 20 of about 223,134 (358)

Brain targeted delivery of rapamycin using transferrin decorated nanostructured lipid carriers [PDF]

open access: yesBioImpacts, 2022
Introduction: Recent studies showed that rapamycin, as a mammalian target of rapamycin (mTOR) inhibitor, could have beneficial therapeutic effects for the central nervous system (CNS) related diseases.
Fatemeh Khonsari   +4 more
doaj   +1 more source

Extraintestinal pathogenic Escherichia coli utilizes the surface-expressed elongation factor Tu to bind and acquire iron from holo-transferrin

open access: yesVirulence, 2022
Extraintestinal pathogenic Escherichia coli (ExPEC) is a common anthropozoonotic pathogen that causes systemic infections. To establish infection, ExPEC must utilize essential nutrients including iron from the host.
Yu Sun   +5 more
doaj   +1 more source

An Improved Method for Quick Quantification of Unsaturated Transferrin

open access: yesBiosensors, 2022
Blood iron levels play a vital role in oxygen metabolism and energy generation whilst transporter protein, transferrin, binds and delivers iron to the transferrin receptor of endosomal compartments of cells.
Ruirui Guo   +8 more
doaj   +1 more source

Novel O-Methylglucoside Derivatives of Flavanone in Interaction with Model Membrane and Transferrin

open access: yesMembranes, 2022
Flavonoids were biotransformed using various microorganisms, in order to obtain new compounds with potentially high biological activity. The aim of this work was to determine and compare the biological activity of four novel 6-methylflavanone O ...
Sylwia Cyboran-Mikołajczyk   +4 more
doaj   +1 more source

In Silico Tools for Analysis of Single-Nucleotide Polymorphisms in the Bovine Transferrin Gene

open access: yesAnimals, 2022
Dairy cattle with a high milk yield are susceptible to many infectious diseases, such as mastitis. Subclinical mastitis (SCM) is the most prevalent form of mastitis that predominantly affects animal health, and causes adverse effects on the quality and ...
Aarif Ali   +7 more
doaj   +1 more source

Topical Intranasal Fluorescein to Diagnose and Localize Cerebrospinal Fluid Leak: A Systematic Review

open access: yesTurkish Archives of Otorhinolaryngology, 2021
Objective:This study evaluates the available evidence regarding using topical intranasal fluorescein (TINF) to diagnose and localize nasal cerebrospinal fluid (CSF) leak.Methods:A literature search was conducted through PubMed, the Cochrane Database ...
Hussain Albaharna   +5 more
doaj   +1 more source

Fibrillation of transferrin [PDF]

open access: yesBiochimica et Biophysica Acta (BBA) - General Subjects, 2012
The nature of fibrillar deposits from aqueous solutions of human serum and recombinant human transferrin on mica and carbon-coated formvar surfaces has been investigated.Atomic force microscopy showed that the deposition of recombinant transferrin onto the hydrophilic surface of mica resulted in the formation of a monolayer-thick film composed of ...
C. Booyjzsen   +6 more
openaire   +2 more sources

Association between systemic iron status and β-cell function and insulin sensitivity in patients with newly diagnosed type 2 diabetes

open access: yesFrontiers in Endocrinology, 2023
ObjectiveAbnormal iron metabolism is related to the risk of diabetes, but the underlying mechanism of this association remains uncertain. This study was conducted to evaluate the contributions of systemic iron status to β-cell function and insulin ...
Yao Qin   +7 more
doaj   +1 more source

Transferrin Insufficiency and Iron Overload in Follicular Fluid Contribute to Oocyte Dysmaturity in Infertile Women With Advanced Endometriosis

open access: yesFrontiers in Endocrinology, 2020
Purpose: To screen out specific protein with different concentration in follicular fluid from advanced endometriosis and determine its direct effect on mouse oocytes matured in vitro.Methods: FF samples were obtained from 25 patients (EMS group, n = 15 ...
Anji Li   +5 more
doaj   +1 more source

Stealthy microbes: How Neisseria gonorrhoeae hijacks bulwarked iron during infection

open access: yesFrontiers in Cellular and Infection Microbiology, 2022
Transition metals are essential for metalloprotein function among all domains of life. Humans utilize nutritional immunity to limit bacterial infections, employing metalloproteins such as hemoglobin, transferrin, and lactoferrin across a variety of ...
Julie Lynn Stoudenmire   +2 more
doaj   +1 more source

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