Results 211 to 220 of about 212,698 (347)

Simvastatin overcomes the pPCK1‐pLDHA‐SPRINGlac axis‐mediated ferroptosis and chemo‐immunotherapy resistance in AKT‐hyperactivated intrahepatic cholangiocarcinoma

open access: yesCancer Communications, EarlyView.
Abstract Background Intrahepatic cholangiocarcinoma (ICC) is a challenging cancer with an increasing incidence. The Phase III TOPAZ‐1/KEYNOTE‐966 study demonstrated chemo‐immunotherapy (CIT) as a significant advancement, potentially replacing traditional chemotherapy for advanced biliary tract cancer.
Jinghan Zhu   +12 more
wiley   +1 more source

Synthetic virus-like gene delivery systems [PDF]

open access: yes, 1994
Birnstiel, Max L.   +6 more
core   +1 more source

Chemically Synthesized LRAD3‐D1 Interacts with N‐Terminal Domain of SARS‐CoV‐2 Spike Protein

open access: yesChemBioChem, EarlyView.
Chemical synthesis, calcium‐templated in‐vitro folding and competitive ELISA assay reveal that only domain 1 of the LRAD3 ectodomain interacts with the severe acute respiratory syndrome‐related corona virus 2 (SARS‐CoV‐2) spike NTD, while domains 2 and 3 do not, providing valuable insight into ACE2‐independent viral entry pathways that may contribute ...
Mrinmoy Jana   +5 more
wiley   +1 more source

Beyond FimH: Diversity and Relevance of Carbohydrate‐Binding Fimbrial Proteins in Escherichia coli

open access: yesChemBioChem, EarlyView.
This review discusses fimbrial lectins found in Escherichia coli (E. coli) other than FimH, which could be targeted to treat E. coli pathogenicity as an alternative to antibiotic treatment. Escherichia coli (E. coli) is responsible for multiple diseases in humans and animals.
Oliwier R. Dulawa   +3 more
wiley   +1 more source

Sex Hormones and Iron-Related Biomarkers Associate with EMT Features and Tumor Stage in Colorectal Cancer: A Serum- and Tissue-Based Analysis. [PDF]

open access: yesInt J Mol Sci
Squitti R   +9 more
europepmc   +1 more source

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