Transferrin-modified multicomponent liposomes encapsulating paclitaxel-loaded <i>β</i>-elemene microemulsion enhance therapeutic efficacy in non-small-cell lung cancer. [PDF]
Chen Y, Zhang Z, Xiong R, Cao Y, Liu Q.
europepmc +1 more source
This work explores the tailored functionalization of mesoporous silica nanoparticles (MSN) to improve the oral delivery of insulin, as a case study. Insulin confinement within silica mesopores increased drug solubility, and co‐formulation with succinylated β‐lactoglobulin yielded pH‐responsive tablets that limited gastric release and proteolysis, while
Claudia Iriarte‐Mesa +14 more
wiley +1 more source
Heterozygous transferrin receptor 1 deletion reduces atherosclerotic lesion formation in apolipoprotein E-deficient mice. [PDF]
Naito Y +3 more
europepmc +1 more source
Activatable smart contrast agents for photoacoustic imaging
This review highlights recent advances in smart activatable photoacoustic imaging (PAI) contrast agents, which dynamically modulate their optical properties in response to external stimuli or microenvironmental cues. It discusses their molecular design, activation mechanisms, biomedical applications, and future prospects for clinically tailored use ...
Donghyeon Oh +5 more
wiley +1 more source
Potential Role of Transferrin and Vascular Cell Adhesion Molecule 1 in Differential Diagnosis Among Patients with Tauopathic Atypical Parkinsonian Syndromes. [PDF]
Madetko-Alster N +4 more
europepmc +1 more source
This study shows that human iPSC‐derived endothelial cells acquire a functional blood–brain barrier phenotype when co‐cultured with brain pericytes and stimulated with CHIR‐99021, a Wnt/β‐catenin activator. This model recapitulates key barrier properties, inflammatory responses, and transcriptomic features of the native human BBB, offering new ...
Henrique Nogueira Pinto +12 more
wiley +1 more source
Isn't it ironic? Functional iron deficiency at the core of Parkinson's disease pathobiology. [PDF]
Peikon I, Andrews NC.
europepmc +1 more source
ABSTRACT This study investigates how phthalate exposure contributes to uterine fibroid (UF) development by studying the effects of the Mono‐(2‐ethyl‐5‐hydroxyhexyl) phthalate (MEHHP), a metabolite of Di(2‐ethylhexyl) phthalate, on myometrial stem cells (MMSCs).
Somayeh Vafaei +6 more
wiley +1 more source
Relationship between physical activity and health-related indicators of iron metabolism: evidence from a large, representative cohort. [PDF]
Wang Z, Wang Y.
europepmc +1 more source

