Results 231 to 240 of about 223,134 (358)

Clathrin couture: Fashioning distinctive membrane coats at the cell surface [PDF]

, 2009
B. M Collins, B. T Kelly, C Raiborg, C. J Merrifield, D Leonard, D Loerke, D. A Sanan, D. K Cureton, E Boucrot, E. M Schmid, F. Z Idrissi, I Gaidarov, J Barroso-Gonzalez, J Heuser, J Heuser, J Rosenbluth, J. Z Rappoport, J. Z Rappoport, K Miller, K. D Bellve, L Hinrichsen, Linton M. Traub, M Ehrlich, M Kaksonen, M Lakadamyali, M. A Puthenveedu, M. C Saleh, N Abe, P Maupin, P Varnai, P. A Keyel, P. A Keyel, R Zoncu, S Mayor, S Saffarian, S. J Mundell, T Akisaka, T Ben-Kasus, T Kirchhausen, T. A Gottlieb, T. F Roth, X Wu   +41 more
core   +4 more sources

Hypoxia‐Induced Histone Lactylation Promotes Ferroptosis in Cardiomyocytes via the Wnt/β‐Catenin Pathway

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT This study investigated the effects of histone lactylation on ferroptosis in hypoxia‐induced cardiomyocytes. A hypoxia model was established in AC16 cells treated with 2‐Deoxy‐D‐glucose (2‐DG, a glucose analogue), ferrostatin‐1 (Fer‐1, a selective ferroptosis inhibitor), lactate (LA), sh‐β‐catenin (shRNA of β‐catenin), or SKL2001 (an agonist ...
Xin‐Hua Zhu, Jing‐Wen Hou, Zhong‐Ying Lv, Ming‐Hui Sun, Xiao‐Yang Zhang, Lei Zhang, Mei Wang   +6 more
wiley   +1 more source

Sulfide silver autometallography to differentiate the ultrastructural localization of iron-carbohydrate complexes inside macrophages. [PDF]

Sci Rep
Cao AM, Duruz J, de Almeida MS, Vanhecke D, Alston AE, Digigow R, Flühmann B, Petri-Fink A, Rothen-Rutishauser B.   +8 more
europepmc   +1 more source

Intracranial glioma xenograft model rapidly reestablishes blood–brain barrier integrity for longitudinal imaging of tumor progression using fluorescence molecular tomography and contrast agents [PDF]

, 2020
Achilefu, Samuel, Carpenter, Julia, Chen, Hong, Habimana-Griffin, LeMoyne, Marsala, Lynne, Mixdorf, Matthew, Prior, Julie, Rubin, Joshua B., Sudlow, Gail, Ye, Dezhuang   +9 more
core   +1 more source

Enrichment of Hyaluronic Acid Binding Tumor Cells by Modulation of Selective Adhesion on Microgel Surfaces

Macromolecular Rapid Communications, EarlyView.
We have developed a thermoresponsive microgel system for the selective enrichment of hyaluronic acid‐binding tumor cells. By modulating the adhesion on the microgel surface via temperature changes from 37°C to 30°C, we demonstrate a novel proof‐of‐principle for separating these tumor cell from white blood cells, which has potential applications in ...
Melanie Schmidt, Dilay Karayel, André Franken, Janita Müller, Laura Hartmann, Klaus Pantel, Tanja Fehm, Hans Neubauer, Stephan Schmidt   +8 more
wiley   +1 more source

A humanized transferrin receptor 1-transferrin model supports functional iron homeostasis and therapeutic delivery across the blood-brain barrier. [PDF]

J Biol Chem
Yesiltepe M, Metkar S, Yin T, Chakraborty I, D'Adamio L.   +4 more
europepmc   +1 more source

Light‐Based Molecular Tools to Precisely Monitor and Operate β‐Adrenoceptors

Medicinal Research Reviews, EarlyView.
ABSTRACT β‐Adrenoceptors are important G protein–coupled receptors involved in cardiovascular, metabolic, and neurological regulation. To study their function with high precision, light‐based molecular tools have been developed offering precise spatiotemporal control.
Ignazzitto Maria Tindara, Gómez‐Santacana Xavier, Llebaria Amadeu, Rovira Xavier   +3 more
wiley   +1 more source

Iron, the Essential Micronutrient: A Comprehensive Review of Regulatory Pathways of Iron Metabolism. [PDF]

Nutrients
Horváth A, Tamási K, Pap R, Jánosa G, Pandur E.   +4 more
europepmc   +1 more source

Enhancing Selective Brain Cancer Therapy: Integrating Nanomedicine and Molecular Dynamics to Target the Cancerous Lipid Composition

Nano Select, EarlyView.
Improving selectivity within therapeutic design is critical to ensure targeted delivery to brain tumors. Targeting the cellular membrane composition distinctive of the blood–brain barrier and brain cancer cells is explored in this review. Nanomedicine can be utilized for precise tumor recognition, and detailed mechanistic interactions of therapeutics ...
Mahnoor Kadri, Dominique de Jong‐Hoogland, Martin B. Ulmschneider   +2 more
wiley   +1 more source

Association between BRINDA-corrected iron metabolism and lung function in the community: the CoLaus|PneumoLaus study. [PDF]

BMC Pulm Med
Touilloux B, Casutt A, Truong MK, Bongard C, Lechartier B, Marques-Vidal P, Vollenweider P, Vaucher J, von Garnier CV.   +8 more
europepmc   +1 more source