Results 251 to 260 of about 137,943 (306)

Transferrin/transferrin receptor-mediated drug delivery

Medicinal Research Reviews, 2002
AbstractSince transferrin was discovered more than half a century ago, a considerable effort has been made towards understanding tranferrin‐mediated iron uptake. However, it was not until recently with the identification and characterization of several new genes related to iron homeostasis, such as the hemochromatosis protein HFE and the iron ...
Zhong Ming Qian
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Transferrin and transferrin receptors update

Free Radical Biology and Medicine, 2019
In vertebrates, transferrin (Tf) safely delivers iron through circulation to cells. Tf-bound iron is incorporated through Tf receptor (TfR) 1-mediated endocytosis. TfR1 can mediate cellular uptake of both Tf and H-ferritin, an iron storage protein. New World arenaviruses, which cause hemorrhagic fever, and Plasmodium vivax use TfR1 for entry into host ...
Hiroshi Kawabata
exaly   +3 more sources

TRANSFERRIN AND TRANSFERRIN RECEPTORS IN CARCINOMA OF THE BREAST

Lancet, The, 1980
Breast tissues from 59 patients were immunohistologically studied for transferrin and transferrin receptors. None of the 8 normal breasts or 22 benign mastopathies, and only 1 of 7 fibroadenomas were reactive for transferrin, but 16 (72.7%) of 22 carcinomas were positive and parallel sections showed histopathologically that the rective areas were ...
W Page Faulk, Bae-Li Hsi
exaly   +3 more sources

The biology of transferrin

Clinica Chimica Acta, 1990
The chemistry and molecular biology of transferrin is discussed. The discussion covers the genetic control of transferrin synthesis, its intracellular synthesis, intra- and extracellular transport, and its interaction with transferrin receptors. The role of transferrin in iron metabolism is evaluated, both with regard to iron uptake by transferrin as ...
J P Van Dijk, H G Van Eijk, J P Van Dijk   +2 more
exaly   +3 more sources

Delivery of drugs, proteins and genes into cells using transferrin as a ligand for receptor-mediated endocytosis [PDF]

Advanced Drug Delivery Reviews, 1994
Transferrin, an iron-transporting serum glycoprotein, is efficiently taken up into cells by the process of receptor-mediated endocytosis. Transferrin receptors are found on the surface of most proliferating cells, in elevated numbers on erythroblasts and
Ernst Wagner, David T Curiel, Matt Cotten   +2 more
exaly   +2 more sources

Function of Transferrin

Nature, 1968
Recent work on the structure and function of transferrin indicates that it is not only an inert carrier of iron but that it has a complex function in the absorption and distribution of iron in the body.
J, Fletcher, E R, Huehns
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Transferrins of Cercopithecinae

Folia Primatologica, 1970
The transferrin phenotypes of 11 species of Cercopithecinae were determined by electrophoresis of plasma, followed by autoradiography. Sialic acid content of transferrins was determined by electrophoresis and autoradiography of enzymatically treated plasma. Transferrin polymorphisms were found in three species.
D, Coppenhaver, J, Buettner-Janusch
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Modulators of macrophage transferrin or transferrin-like protein

Molecular and Cellular Biochemistry, 1990
The effects of endotoxin or testosterone on the amount of transferrin 59Fe (or like protein) in the murine macrophages was investigated. The mouse peritoneal macrophages were laden with 59Fe tagged red cells following the injection of mice with either agent.
F I, Haurani, T J, Quinn
openaire   +2 more sources