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Transferrin receptor 2 mediates uptake of transferrin-bound and non-transferrin-bound iron

open access: yesJournal of Hepatology, 2008
Background/Aims: Transferrin receptor 2 appears to have dual roles in iron metabolism; one is signalling, the other is iron transport. It is sensitive to high levels of diferric transferrin, which is associated with disorders of iron overload.
Ross M Graham   +2 more
exaly   +1 more source
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CSF transferrins characterized by the transferrin/albumin index

Clinica Chimica Acta, 1980
Unconcentrated CSF and 200 times diluted serum samples from 192 patients were examined by agar electrophoresis; their albumin and transferrin content were determined simultaneously by radial immunodiffusion. Using the data on transferrin and albumin concentrations in serum and cerebrospinal fluid, the transferrin/albumin index was calculated in a ...
L, Kerényi, M, Koltai, I, Szirmai
openaire   +2 more sources

Transferrin toxin but not transferrin receptor immunotoxin is influenced by free transferrin and iron saturation

European Journal of Clinical Investigation, 2002
AbstractBackground  Cytotoxic agents can be targeted successfully to cancer cells. The efficacy of such novel and potent anticancer strategies may be influenced by variables of iron metabolism.Methods  The in vitro cytotoxicity against glioma cells of transferrin (Tf)‐based targeted toxins was compared with that of α‐transferrin receptor (TfR ...
P H, Gosselaar   +8 more
openaire   +2 more sources

The Transferrin Receptor and the Release of Iron from Transferrin

1994
In a classic report detailing the role of transferrin in providing iron to human reticulocytes, Jand1 and coworkers noted that uptake of transferrin-borne iron was saturable as the concentration of transferrin in the culture medium increased, and that uptake was essentially abolished if cells were first exposed to trypsin.
openaire   +2 more sources

Serum Transferrins

Nature, 1959
E R, GIBLETT, C G, HICKMAN, O, SMITHIES
openaire   +2 more sources

Transferrin oversaturation

American Journal of Kidney Diseases, 1999
J, Strobos   +3 more
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Human transferrin: An inorganic biochemistry perspective

Coordination Chemistry Reviews, 2021
André M N Silva   +2 more
exaly  

Transferrine

EMC - Biologie Médicale, 2006
Marie-Claude Revenant, C. Doyen
openaire   +1 more source

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