Results 71 to 80 of about 212,698 (347)

Iron metabolism and laboratory testing for iron status [PDF]

Medicinski Podmladak, 2016
Under normal circumstances, 1-2 mg of iron enters and leaves the body each day. Iron is absorbed in the duodenum, as heme and non-heme iron (Fe+2). Due to its ability to participate in redox-reactions, iron possesses toxic properties.
Ćorić Vesna
doaj   +1 more source

Immunonephelometric Carbohydrate-Deficient Transferrin Results and Transferrin Variants [PDF]

Clinical Chemistry, 2013
To the Editor: Carbohydrate-deficient transferrin (CDT)1 is a biomarker of growing importance in the assessment of alcohol abuse after conviction for drunk driving. CDT is a more specific indicator for alcohol than traditional liver function tests and is used for identification and follow-up of chronic high alcohol consumption (1).
Marc De Buyzere, Elke Lecocq, Thomas M. Maenhout, Joris R. Delanghe, Marc Uytterhoeven   +4 more
openaire   +3 more sources

A Vascularized Microphysiological System Reproducing Endochondral Ossification in Vitro to Study Ewing Sarcoma Proliferation and Migration

Advanced Functional Materials, EarlyView.
A biofabricated 3D in vitro model recapitulating endochondral ossification (ECO) is described, mimicking the steps from condensation to chondrogenesis and hypertrophy, culminating with vascularization of the hypertrophic construct. As a model proof of concept application, Ewing Sarcoma cells are seeded in the model, showing modifications in their ...
Maria Vittoria Colombo, Chiara Arrigoni, Tobias Faehling, Antonietta Verrillo, Viviana Secci, Thomas G. P. Grünewald, Giuseppe Talò, Alexandra Kummer, Jorge Gonzalez, Vincenzo De Rosa, Christian Candrian, Andrea Barbero, Florencia Cidre‐Aranaz, Matteo Moretti   +13 more
wiley   +1 more source

Evaluation of a PACAP Peptide Analogue Labeled with (68)Ga Using Two Different Chelating Agents. [PDF]

, 2016
OBJECTIVE: The authors have conjugated chelating agents (DOTA and NODAGA) with a peptide (pituitary adenylate cyclase-activating peptide [PACAP] analogue) that has a high affinity for VPAC1 receptors expressed on cancer cells.
Chen, Chang-Po, Kumar, Pardeep, Mehta, Neil, Paudyal, Bishnuhari, Thakur, Mathew L., Tripathi, Sushil Kumar, Wickstrom, Eric   +6 more
core   +2 more sources

Optimizing Angiopep‐2 Density on Polymeric Nanoparticles for Enhanced Blood–Brain Barrier Penetration and Glioblastoma Targeting: Insights From In Vitro and In Vivo Experiments

Advanced Functional Materials, EarlyView.
The Angiopep‐2 peptide density on polymeric nanoparticles significantly impacts blood–brain barrier (BBB) penetration. This study explores this nuanced relationship using various in vitro models and in vivo assays, revealing that dynamic models better predict BBB penetration.
Weisen Zhang, Ahmed Refaat, Haoqin Li, Douer Zhu, Ziqiu Tong, Joseph Anthony Nicolazzo, Bo Peng, Hua Bai, Lars Esser, Nicolas Hans Voelcker   +9 more
wiley   +1 more source

High-efficiency receptor-mediated delivery of small and large (48 kilobase gene constructs using the endosome-disruption activity of defective or chemically inactivated adenovirus particles. [PDF]

, 1992
The Boltzmann transport equation is commonly considered to be the best semi-classical description of carrier transport in semiconductors, providing precise information about the distribution of carriers with respect to time (one dimension), location ...
Birnstiel, Max L., Cotten, Matt, Curiel, David T., Phillips, Stephen, Wagner, Ernst, Zatloukal, Kurt   +5 more
core   +2 more sources

Tunable Thermoshrinkable Hydrogels for 4D Fabrication of Cell‐Seeded Channels

Advanced Functional Materials, EarlyView.
A thermoresponsive polymer with methacrylate groups for photo‐cross‐linking, based on polyethylene glycol, N‐isopropylacrylamide, and 2‐hydroxyethyl acrylate is synthetized to yield hydrogels that shrink upon temperature increase. The new polymer enables the fabrication of cell‐laden perfusable channels with diameters below 200 µm by combining ...
Greta Di Marco, Marc Falandt, Myriam Neumann, Martina Viola, Thibault Sampon, Marta G. Valverde, Anne Metje van Genderen, Silvia M. Mihaila, Cornelus F. van Nostrum, Bas G. P. van Ravensteijn, Riccardo Levato, Rosalinde Masereeuw, Tina Vermonden   +12 more
wiley   +1 more source

Transducer Materials Mediated Deep Brain Stimulation in Neurological Disorders

Advanced Functional Materials, EarlyView.
This review discusses advanced transducer materials for improving deep brain stimulation (DBS) in neurological disorders. These materials respond to light, ultrasound, or magnetic fields, enabling precise, less invasive neuromodulation. Their stimulus‐responsive properties enhance neural control and adaptive therapy, paving the way for next‐generation ...
Di Zhao, Zhengyang Cao, Guangjun Zhong, Limin Shi, Junxia Xie, Jianhua Hao   +5 more
wiley   +1 more source

Transferrin and Lactoferrin – Human Iron Sources for Enterococci [PDF]

Polish Journal of Microbiology, 2017
To overcome limitations in iron acquisition, enterococci have evolved a number of mechanisms to scavenge iron from the host iron-binding proteins – transferrin (TR) and lactoferrin (LF).
Paweł Lisiecki
doaj   +1 more source

Activation of endocytosis as an adaptation to the mammalian host by trypanosomes [PDF]

, 2007
Immune evasion in African trypanosomes is principally mediated by antigenic variation, but rapid internalization of surface-bound immune factors may contribute to survival.
Field, Mark C, Gibson, Wendy, Matthews, Keith, Natesan, Senthil Kumar A, Peacock, Lori   +4 more
core   +2 more sources