Results 101 to 110 of about 2,476,356 (396)

THE ROLE OF SERUM TRANSFERRIN RECEPTORS MEASUREMENT

Zdravniški Vestnik, 2004
Background. The transferrin receptors are transmembrane proteins. They have a critical role in iron metabolism by controlling the flow of transferrin iron into body cells.
Bernarda Vogrin, Matjaž Vogrin, Mirjana Miksić, Zdravko Roškar, Mira Šauperl   +4 more
doaj  

Characterization of Tfrc-mutant mice with microcytic phenotypes

Blood Advances, 2018
: To identify novel regulators of erythropoiesis, we performed independent forward genetic screens using the chemical mutagen ENU in mice. Among progeny displaying microcytic red-cell phenotypes, 7 independent mouse strains harboring mutations within the
Ashlee J. Conway, Fiona C. Brown, Gerhard Rank, Benjamin T. Kile, Craig J. Morton, Stephen M. Jane, David J. Curtis   +6 more
doaj   +1 more source

Mechanism of active targeting in solid tumors with transferrin-containing gold nanoparticles [PDF]

, 2010
PEGylated gold nanoparticles are decorated with various amounts of human transferrin (Tf) to give a series of Tf-targeted particles with near-constant size and electrokinetic potential.
C. A. Alabi, C. H. J. Choi, Danscher, Davis, Dreher, Farokhzad, Gatter, Hu-Lieskovan, Ishida, Jiang, Kirpotin, Lopes de Menezes, M. E. Davis, Matsumura, Montet, P. Webster, Park, Perrault, Popielarski, Sawyer, Schmidt, Stein, Zhou   +22 more
core   +2 more sources

Intrinsically Disordered Protein‐Inspired Nanovector‐Based Coacervates for the Direct Cytosolic Transport of Biomacromolecules

Advanced Materials, EarlyView.
Intrinsically disordered protein‐inspired nanovectors (IDP‐NVs) form stable nanocoacervates (NCs) with diverse biomacromolecules. In situ conformational changes confer stability and adaptability to NCs under dynamically changing physiological conditions.
Soyeong Jin, Hyemin Park, Seuk‐Min Ryu, Dagyeong Guk, Jaeeun Lee, Seongeon Jin, Changjoon Keum, Jinyoung Park, Myoung‐Hwan Park, Chaekyu Kim, Hojun Kim, Jaegeun Noh, Kwan Hyi Lee, Ja‐Hyoung Ryu, Youngdo Jeong   +14 more
wiley   +1 more source

Disruption of HOX activity leads to cell death that can be enhanced by the interference of iron uptake in malignant B cells. [PDF]

, 2010
The HOX genes encode a family of transcription factors that are dysregulated in several malignancies and have been implicated in oncogenesis and cancer cell survival.
Daniels, TR, Morgan, R, Neacato, II, Pandha, HS, Penichet, ML, Rodríguez, JA   +5 more
core   +1 more source

Transferrin‐Directed Internalization and Cycling of Transferrin Receptor 2 [PDF]

Traffic, 2009
Transferrin receptor 2 (TfR2) is a homologue of transferrin receptor 1 (TfR1) but has distinct functions from TfR1 in iron homeostasis. In keeping with its proposed role in iron sensing, previous studies showed that TfR2 has a short half‐life and that holo‐Tf stabilizes TfR2 by redirecting it from a degradative pathway to a recycling pathway.
Juxing, Chen, Jinzhi, Wang, Kathrin R, Meyers, Caroline A, Enns   +3 more
openaire   +2 more sources

Kelvin Probe Force Microscopy in Bionanotechnology: Current Advances and Future Perspectives

Advanced Materials, EarlyView.
Kelvin probe force microscopy (KPFM) enables the nanoscale mapping of electrostatic surface potentials. While widely applied in materials science, its use in biological systems remains emerging. This review presents recent advances in KPFM applied to biological samples and provides a critical perspective on current limitations and future directions for
Ehsan Rahimi, Mario Palacios‐Corella, Arjan Mol, Salvador Pané, Josep Puigmartí‐Luis   +4 more
wiley   +1 more source

HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface [PDF]

, 2004
Transferrin receptor (TfR) is a dimeric cell surface protein that binds both the serum iron transport protein transferrin (Fe-Tf) and HFE, the protein mutated in patients with the iron overload disorder hereditary hemochromatosis.
Bjorkman, Pamela J., Giannetti, Anthony M.   +1 more
core   +2 more sources

Mesenchymal Stem Cell‐Inspired Microneedle Platform for NIR‐responsive Immunomodulation and Accelerated Chronic Wound Healing

Advanced Materials, EarlyView.
The research demonstrates a Mesenchymal Stem Cell‐inspired microneedle platform (MSCi@MN) that addresses chronic diabetic wounds by combining MSC‐derived extracellular nanovesicles (NV)–DNA conjugates in microneedle tips with photothermal MXene in the patch layer.
Chan Ho Moon, Hee Gyeong Ko, Hyun Lee, Seojoon Bang, Hyeong Seok Kang, Ju Yeong Gwon, Jong Hwa Seo, Nayoung Lee, So Won Jeon, Yun‐A Kim, Jong Sang Yoon, Kyung‐Yup Cha, Min‐Ho Kang, Dong Yun Lee, Soo‐Hong Lee, Gi Doo Cha, Kisuk Yang, Donghyun Lim, Heemin Kang, Su Ryon Shin, Han Young Kim, Hyun‐Do Jung   +21 more
wiley   +1 more source

Mutations in human dynamin block an intermediate stage in coated vesicle formation [PDF]

, 1993
The role of human dynamin in receptor-mediated endocytosis was investigated by transient expression of GTP-binding domain mutants in mammalian cells. Using assays which detect intermediates in coated vesicle formation, the dynamin mutants were found to ...
Damke, Hanna, Meyerowitz, Elliot M., Redelmeier, Thomas E., Schmid, Sandra L., Tisdale, Ellen J., van der Bliek, Alexander M.   +5 more
core   +3 more sources