Results 201 to 210 of about 133,411 (307)

New Transferrin Receptor-Targeting Conjugate Effectively Delivers DNA to Mouse Brain. [PDF]

Angew Chem Int Ed Engl
Song MS, Bustos AH, Bastue L, Mikutavicius J, Swiderski P, Clemens KJ, Habib N, Rossi J, Astakhova K.   +8 more
europepmc   +1 more source

Pharmacological effects of gastrodin: Insight into neurological diseases and mechanism in ferroptosis and pyroptosis

Ibrain, Volume 11, Issue 1, Page 74-83, Spring 2025.
Pharmacological effects of gastrodin include prevention and treatment of cognitive decline and reperfusion injuries, anticonvulsion, antiepilepsy, antidepressants, and analgesia, which are related to antiferroptosis and antipyroptosis. Abstract Gastrodin, as an effective monomer of gastrodia elata, plays a significant role in anti‐inflammatory ...
Xue Zheng, Jing Li, Zhao‐Qiong Zhu
wiley   +1 more source

Design and Preclinical Evaluation of a ⁶⁸Ga-Labeled Macrocyclic Peptide PET Probe Targeting Transferrin Receptor 1 in Colorectal Cancer. [PDF]

ACS Omega
Zhu Y, Wang L, Tang Q, Wang J, Zhang X, Deng S, Yang Y.   +6 more
europepmc   +1 more source

Combination of Lenvatinib and Antibiotics: A Potential Approach to Enhance Sensitivity in Differentiated Thyroid Cancer

International Journal of Cancer, EarlyView.
Although lenvatinib is the current first‐line therapy for radioiodine‐refractory differentiated thyroid carcinoma, its use is limited by severe side effects and reduced sensitivity. Here, the authors assessed the potential of sensitizing differentiated thyroid carcinoma tumor cells with limited lenvatinib responsiveness through the administration of ...
Celina Ablinger, Petra Huber‐Cantonati, Daniela D. Weber, Sarah Pichler, Georg Schischkow, Marta Garcia‐Miralles, Christian Pirich, Gundula Rendl, Teresa Kiener, Thomas Felder, Martin Geroldinger, Robert Terkola, Barbara Kofler, Johanna Pachmayr   +13 more
wiley   +1 more source

High-affinity transferrin receptor binding improves brain delivery of bispecific antibodies at tracer dose. [PDF]

Fluids Barriers CNS
Bonvicini G, Singh S, Sandersjöö L, Dallas T, Schlein E, Dahlén AD, Lopes van den Broek S, Sehlin D, Andersson KG, Syvänen S.   +9 more
europepmc   +1 more source

Iron deficiency with and without anemia in pregnancy: A scoping review of prevalence and perinatal impact

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Background The prevalence of iron deficiency with anemia and iron deficiency without anemia (IDWA) during pregnancy have not been summarized, and evidence of the direct association of IDWA with adverse perinatal outcomes (APO) are unknown.
Lucky O. Lawani, David M. Naimark, Joel G. Ray, Jessica Widdifield, Paul Eze, Chidumebi J. Idemili, Nadine Shehata   +6 more
wiley   +1 more source

Investigating the relationship between peripheral blood transferrin receptor protein and tumor cell ferroptosis, invasion, and metastasis in bladder cancer. [PDF]

Sci Rep
Zhao L, Xu Z, Ren L, Zheng S, Gao J, Che H, Zhang A.   +6 more
europepmc   +1 more source

Ovarian Cancer: Epidemiology, Disease Mechanisms, New Diagnosis and Treatment Strategies, and Research Directions

iNew Medicine, EarlyView.
ABSTRACT Ovarian cancer (OC) continues to be the deadliest gynecological malignancy and a significant cause of cancer‐related mortality among women worldwide. Standard treatment strategies typically entail platinum‐based chemotherapy in conjunction with cytoreductive surgery.
Zunera Khalid, Weirong Fan, Farah Nazir, Yixiang Xing, Tengchuan Jin   +4 more
wiley   +1 more source

Serotransferrin enhances transferrin receptor-mediated brain uptake of antibodies. [PDF]

Drug Deliv Transl Res
Morrison JI, Metzendorf NG, Liu J, Hultqvist G.   +3 more
europepmc   +1 more source

N6‐Methyladenosine (m6A) in Liver Disease: Pathogenic Mechanisms and Therapeutic Potential

iNew Medicine, EarlyView.
ABSTRACT Accumulating evidence highlights the critical role of epigenetic modifications, particularly N6‐methyladenosine (m6A), in liver disease. As the most abundant RNA modification in eukaryotic cells, m6A is dynamically regulated by multicomponent m6A methyltransferases (e.g., METTL3 and METTL14), demethylases (FTO and ALKBH5), and m6A‐binding ...
Yingfen Chen, Ru Ya, Ziling Zhang, Siyue Dong, Seol Hee Park, Wonhyo Seo, Yong He   +6 more
wiley   +1 more source