Results 31 to 40 of about 4,779 (181)

PK and PK/PD Modeling of Bcl2 Inhibitor S65487 in Patients With AML and Investigation of Nonlinearity With Microdosing

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 7, July 2026.
ABSTRACT This work aims to assess the S65487‐induced disruption of the B‐cell lymphoma‐2 (Bcl2)/Bcl2‐like protein 11 (Bim) complex at therapeutic doses via a pharmacokinetic/pharmacodynamic model and to reconcile pharmacokinetic data from microdoses and therapeutic doses in a single population pharmacokinetic model. The first model consists of a linear
Chloé Burlot   +6 more
wiley   +1 more source

Abnormal cleavage patterns in equine in vitro‐produced embryos lead to higher early pregnancy loss

open access: yesEquine Veterinary Journal, Volume 58, Issue 4, Page 970-980, July 2026.
Summary Background Despite significant advances, in vitro production (IVP) of equine embryos continues to lack standardised embryo classification criteria and is associated with increased rates of early pregnancy loss compared with in vivo‐derived blastocysts.
Soledad Martin‐Pelaez   +6 more
wiley   +1 more source

L' enseignement plurilingue du point de vue de l'apprenant

open access: yesLangue(s) & Parole, 2017
Ce texte retrace de façon synthétique des expériences de recherche sur une vingtaine d’années avec des classes africaines monolingues et bilingues en contexte plurilingue.
Colette Noyau
doaj   +1 more source

Luxembourg Has Spoken: Polish and Dutch Judges' Satisfaction With Rule of Law Judgements of the Court of Justice of the EU

open access: yesJCMS: Journal of Common Market Studies, Volume 64, Issue 4, Page 1405-1430, July 2026.
Abstract The last decade has witnessed a substantial increase in case law of the Court of Justice of the European Union (hereafter: ECJ or Court) concerning the rule of law. This expansion in case law reflects the significant challenges to the rule of law that have arisen in recent years. Several EU member states have implemented measures that severely
Urszula Jaremba, Jasper Krommendijk
wiley   +1 more source

La bilittératie chez les élèves allophones en milieu scolaire montréalais : une réflexion pour améliorer l’enseignement-apprentissage du français

open access: yesCanadian Journal for New Scholars in Education, 2015
Dans le présent texte, nous poursuivons un double objectif. Le premier est de rendre compte de l’importance du concept de bilittératie pour la recherche et la pratique en éducation.
Abdel Hakim Touhmou
doaj  

Un chercheur racisé face à une subjectivité raciale différenciée : approche clinique et réflexive du racisme

open access: yesClinical Sociology Review
Pour un chercheur racisé, à enquêter sur le racisme peut sembler périlleux du point de vue du rapport à l’objet que requiert une démarche d’objectivation scientifique.
Rachid Bouchareb
doaj   +1 more source

Fonction et champ de la lettre dans la clinique du trauma et du transfert [PDF]

open access: yesRevista Latinoamericana de Psicopatologia Fundamental
Le constat de la traversée analytique de la lettre, dont Lacan s’est saisi pour mettre en lumière les modalités de manifestation de l’inconscient, incite à nous pencher sur ses apports, plus spécifiquement dans le champ d’une clinique à l’épreuve du ...
Charlotte Collet   +3 more
doaj   +1 more source

Powering Nanocrystal‐Based Heat Engines With Light‐Emitting Metasurfaces That Influence Their Temperature

open access: yesAdvanced Functional Materials, Volume 36, Issue 52, 29 June 2026.
Metasurfaces and other structured photonic environments can dramatically modify the absorption and/or light emission of semiconductors. However, the consequences of these changes on the temperature of the system are not well understood. The authors address this problem for colloidal nanocrystals and leverage their findings to convert light into ...
Hugo Kowalczyk   +7 more
wiley   +1 more source

Une clinique possible avec les malades d’Alzheimer

open access: yesRevista Latinoamericana de Psicopatologia Fundamental, 2015
Dans cet article les auteurs montrent qu’une psychothérapie d’inspiration psychanalytique est possible avec des sujets institutionnalisés présentant une démence du type Alzheimer.
Cristina Fontela, Thierry Darnaud
doaj   +1 more source

From passion to illegality: Understanding succulent consumers' decision to participate in the illegal online wildlife trade

open access: yesPeople and Nature, Volume 8, Issue 6, Page 1773-1784, June 2026.
Abstract The illegal wildlife trade represents a significant threat to biodiversity. Limited research has examined the illegal trade in succulents, plants characterized by their ability to store water in their leaves, stems or roots. The growing popularity of succulents has contributed to the emergence of illicit consumer practices.
Léanne Vincendon   +2 more
wiley   +1 more source

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