Results 91 to 100 of about 5,482,088 (343)

Bacterial gene transfer by natural genetic transformation in the environment.

Microbiological reviews, 1994
Natural genetic transformation is the active uptake of free DNA by bacterial cells and the heritable incorporation of its genetic information. Since the famous discovery of transformation in Streptococcus pneumoniae by Griffith in 1928 and the ...
M. G. Lorenz, W. Wackernagel
semanticscholar   +1 more source

Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation

FEBS Letters, EarlyView.
The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt, Marcus S. Münchhoff, Jacqueline Krohn, Philip M. Palarz, Manuel H. Taft, Johannes N. Greve, Nataliya Di Donato, Falk F. R. Buettner, Dietmar J. Manstein   +8 more
wiley   +1 more source

Inhibition of oxidative metabolism leads to p53 genetic inactivation and transformation in neural stem cells [PDF]

, 2015
The final published version can be found here: http://dx.doi.org/10.1073/pnas ...
Anna Karlsson, Choksi, Deli A, Jayeta Saxena, Joanne Betts, Kiebish, Kim, L. Miguel Martins, Melania Capasso, Nick V. Henriquez, Paolo Salomoni, Pierluigi Nicotera, Sara Galavotti, Schwartzbaum, Sebastian Brandner, Stefano Bartesaghi, Valentina Minieri, Vincenzo De Laurenzi, Vincenzo Graziano   +18 more
core   +1 more source

Genetic transformation of barley: limiting factors

Biologia Plantarum, 2011
This review summarizes main difficulties involved in barley (Hordeum vulgare L.) transformation. The most commonly used procedures for genetic transformation in barley are Agrobacterium tumefaciens and particle bombardment mediated methods.
Š. Vyroubalová, M. Šmehilová, P. Galuszka, L. Ohnoutková   +3 more
doaj   +1 more source

Research Progress on Tissue Culture and Genetic Transformation of Ramie

Journal of Natural Fibers, 2020
Ramie is a perennial bast fiber crop. Plant tissue culture and genetic transformation have become powerful tools for scientific research and important means of agricultural production.
Xia An, Guanrong Jin, Xiahong Luo, Changli Chen, Wenlue Li, Guanlin Zhu   +5 more
doaj   +1 more source

Purification tags markedly affect self‐aggregation of CPEB3

FEBS Letters, EarlyView.
Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito, Yujin Lee, Motoharu Ueno, Naotaka Sekiyama, Masatomo So, Ayako Furukawa, Kenji Sugase   +6 more
wiley   +1 more source

Potato R1 resistance gene confers resistance against Phytophthora infestans in transgenic tomato plants [PDF]

, 2010
Tomato is challenged by several pathogens which cause loss of production. One such pathogen is the oomycete Phytophthora infestans which is able to attack all the aerial parts of the plant.
Carli, P., Cristinzio, G., Ercolano, M.R., Faino, L., Frusciante, L., Testa, A.   +5 more
core   +3 more sources

Insights into pegRNA design from editing of the cardiomyopathy‐associated phospholamban R14del mutation

FEBS Letters, EarlyView.
This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao, Qiangbing Yang, Christian J.B. Snijders Blok, Mark A. Daniels, Pieter A. Doevendans, Raymond Schiffelers, Joost P.G. Sluijter, Zhiyong Lei   +7 more
wiley   +1 more source

The genetic transformation of plastids

, 2007
Biolistic delivery of DNA initiated plastid transformation research and still is the most widelyused approach to generate transplastomic lines in both algae and higher plants. The principal designof transformation vectors is similar in both phylogenetic groups.
Hans-Ulrich Koop, Timothy J. Golds, Jörg Nickelsen, Stefan Herz   +3 more
openaire   +2 more sources

Improving genetic transformation rates in honeybees

Scientific Reports, 2018
Functional genetic studies in honeybees have been limited by transformation tools that lead to a high rate of transposon integration into the germline of the queens.
M. Otte, O. Netschitailo, O. Kaftanoglu, Y. Wang, R. E. Page Jr., M. Beye   +5 more
doaj   +1 more source