Results 71 to 80 of about 137,655 (309)

An Interpretation on Kinetics of Martensitic Transformation

, 2011
We have investigated athermal and isothermal martensitic transformations (typical displacive transformations) in Fe–Ni, Fe–Ni–Cr, and Ni-Co-Mn-In alloys under magnetic fields and hydrostatic pressures in order to understand the time-dependent nature of ...
Takashi Fukuda, Tomoyuki Kakeshita, Yong-Hee Lee   +2 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

Phase transformation kinetics model for metals

International Journal of Plasticity
We develop a new model for phase transformation kinetics in metals by generalizing the Levitas-Preston (LP) phase field model of martensite phase transformations (see Levitas and Preston (2002a,b); Levitas, Preston and Lee (2003)) to arbitrary pressure.
Daniel N. Blaschke, Abigail Hunter, Dean L. Preston   +2 more
openaire   +2 more sources

Kinetics of phase transformations in depletion-driven colloids

Physical Review E, 2004
We present results from a detailed numerical study of the kinetics of phase transformations in a model two-dimensional depletion-driven colloidal system. Transition from a single, dispersed phase to a two-phase coexistence of monomers and clusters is obtained as the depth of the interaction potential among the colloidal particles is changed. Increasing
Cerdà, Joan J., Sintes, Tomàs, Sorensen, C. M., Chakraborti, Anirban   +3 more
openaire   +3 more sources

Kinetics of bainite transformation in heterogeneous microstructures

, 2012
International audienceIn classical models for microstructural evolution, the natural dispersion existing in the samples is often neglected. In this paper, we propose a general procedure that takes into account the distribution of austenite grain size on ...
Bouaziz, Olivier, Takahashi, M., S. Allain, M. Gouné, K. Zhu, M. Takahashi, Allain, S., Gouné, M., O. Bouaziz, Zhu, Kangying   +9 more
core   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Transformation kinetics in partially crystallized amorphous alloys —a theoretical approach

, 2002
A model for the kinetics of phase transformation in amorphous alloys is proposed. The theoretical approach takes into account microstructural changes occurring during transformation and the interaction of as-created nuclei and growing crystallites with
H. Hermann
core   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Quantitative Assessment of the Time to End Bainitic Transformation

Metals, 2019
Low temperature bainite consists of an intimate mixture of bainitic ferrite and retained austenite, usually obtained by isothermal treatments at temperatures close to the martensite start temperature and below the bainite start temperature.
Miguel A. Santajuana, Adriana Eres-Castellanos, Victor Ruiz-Jimenez, Sebastien Allain, Guillaume Geandier, Francisca G. Caballero, Carlos Garcia-Mateo   +6 more
doaj   +1 more source

Epigenetic heterogeneity and plasticity in therapy‐induced tumor states through single‐cell multi‐omics

Molecular Oncology, EarlyView.
Single‐cell multi‐omics reveals epigenetic heterogeneity across therapy‐adaptive tumor states, including quiescent/dormant, drug‐tolerant persister, and EMT‐like phenotypes. By linking regulatory features with state‐associated biomarkers, these approaches inform biomarker‐guided therapeutic strategies for evolving tumors.
Hee Jung Kim, Hwiyeong Lee, Jin Hong, Daechan Park   +3 more
wiley   +1 more source