Results 81 to 90 of about 2,437,366 (312)

The political dimension of dance : Mouffe’s theory of agonism and choreography [PDF]

open access: yes, 2017
In order to support this argument, I will first turn to the quasi-transcendental philosophical trajectory developed by the French philosopher, Jacques Derrida, before then turning to examine post-foundational politico-philosophical thought, which ...
Petrović, Goran
core   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

Transformation of normative personality in Russian society [PDF]

open access: yes, 2015
The aim of the study is to identify the characteristics of normative personality in the different periods of the history of Russian society. The author's methods are comparative analysis and in-depth interview method.
Makarova, L., Макарова, Л. В.
core  

Recurrent cancer‐associated ERBB4 mutations are transforming and confer resistance to targeted therapies

open access: yesMolecular Oncology, EarlyView.
We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala   +15 more
wiley   +1 more source

Civil Society and Conflict Transformation in Abkhazia, Israel/Palestine, Nagorno-Karabakh, Transnistria and Western Sahara [PDF]

open access: yes
The paper describes and analyses the role of civil society in five conflict cases – Abkhazia, Nagorno-Karabakh, Transnistria, Western Sahara and Israel/ Palestine. It evaluates the relative effectiveness of civil society organisations (CSOs) and assesses
Nicoletta Pirozzi, Nona Mikhelidze
core  

Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer

open access: yesMolecular Oncology, EarlyView.
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta   +10 more
wiley   +1 more source

Evolving spatialities of digital life: Troubling the smart city/home divide

open access: yesDigital Geography and Society
While feminist geographers have long aimed to trouble conceptions of the city/home (and, by extension, public/private) divides, the digital city and the digital home are still often theorized as separate phenomena within much digital geography literature.
Casey R. Lynch, Miriam E. Sweeney
doaj   +1 more source

The role of E+A and post-starburst galaxies – I. Models and model results [PDF]

open access: yes, 2009
‘The definitive version is available at www3.interscience.wiley.com '. Copyright Royal Astronomical Society. DOI: 10.1111/j.1365-2966.2009.14416.xDifferent compositions of galaxy types in the field in comparison to galaxy clusters as described by the ...
Falkenberg, M.A.   +2 more
core   +2 more sources

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

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