Results 81 to 90 of about 2,107,464 (275)

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Identification of Power Network Branch Parameters Based on State Space Transformation

IEEE Access, 2019
Deviations or errors in power system branch parameters will seriously affect the effectiveness of power system state estimation and subsequent advanced applications.
Haibo Zhang, Zhiwei Diao, Yunfeng Cui
doaj   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

The review and development of a modern GNSS network and datum in Uzbekistan

Geodesy and Geodynamics, 2017
This study is focused on the discussion of a modern GNSS network and datum in Uzbekistan. Considering the significance difference (up to 200 m) in positions of the local ellipsoidal datum and the global datum, the precise transformation parameters ...
Dilbarkhon Fazilova
doaj   +1 more source

Twisted Hopf symmetries of canonical noncommutative spacetimes and the no-pure-boost principle

, 2007
We study the twisted-Hopf-algebra symmetries of observer-independent canonical spacetime noncommutativity, for which the commutators of the spacetime coordinates take the form [x^{mu},x^{nu}]=i theta^{mu nu} with observer-independent (and coordinate ...
Antonino Marcianò, Fabio Briscese, Flavio Mercati, Giovanni Amelino-Camelia, Giulia Gubitosi, Pierre Martinetti, S. Majid   +6 more
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

Molecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad, Rhiannon Newman, Elmira Khabusheva, Sofia Aakko, Eric Durand, Mahesh Tambe, Heikki Kuusanmäki, Alun Parsons, Juho J. Miettinen, Komal Kumar Javarappa, Ezgi June Olgac, Nemo Ikonen, Mika Kontro, Kimmo Porkka, Heiko Maacke, Janghee Woo, Ensar Halilovic, Caroline A. Heckman   +17 more
wiley   +1 more source

Dual-quaternion-based iterative algorithm of the three dimensional coordinate transformation

Earth, Planets and Space
Nowadays a unit quaternion is widely employed to represent the three-dimensional (3D) rotation matrix and then applied to the 3D similarity coordinate transformation.
Huaien Zeng, Zhihao Wang, Junfeng Li, Siyang Li, Junjie Wang, Xi Li   +5 more
doaj   +1 more source

Improved Parameter Estimation of the Line-Based Transformation Model for Remote Sensing Image Registration

Journal of Imaging, 2017
The line-based transformation model (LBTM), built upon the use of affine transformation, was previously proposed for image registration and image rectification. The original LBTM first utilizes the control line features to estimate six rotation and scale
Ahmed Shaker, Said M. Easa, Wai Yeung Yan   +2 more
doaj   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Quantitative Analysis of 4 × 4 Mueller Matrix Transformation Parameters for Biomedical Imaging

Photonics, 2019
Mueller matrix polarimetry is a potentially powerful technique for obtaining microstructural information of biomedical specimens. Thus, it has found increasing application in both backscattering imaging of bulk tissue samples and transmission microscopic
Wei Sheng, Weipeng Li, Ji Qi, Teng Liu, Honghui He, Yang Dong, Shaoxiong Liu, Jian Wu, Daniel S. Elson, Hui Ma   +9 more
doaj   +1 more source