Results 31 to 40 of about 213,947 (298)

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Fostering creativity and innovation though leadership and affective commitment: The moderated mediation analysis. [PDF]

open access: yesAfrican Journal of Hospitality, Tourism and Leisure, 2019
Leadership and individual commitment are important for creativity and innovation. However, little work has been reported on how transformational leadership interact with affective commitment to influence these constructs. The purpose of this paper was to
Peter Khaola
doaj  

The newfound relationship between extrachromosomal DNAs and excised signal circles

open access: yesFEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Transformational Leadership, Task-Involving Climate, and Their Implications in Male Junior Soccer Players: A Multilevel Approach [PDF]

open access: yes, 2019
Despite the well-known positive consequences of transformational coaches in sport, there is still little research exploring the mechanisms through which coaches’ transformational leadership exerts its impact on athletes.
Castillo, Isabel   +3 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Pengaruh Kepemimpinan Transformasional, Budaya Organisasi, dan Motivasi terhadap Perilaku Berbagi Pengetahuan

open access: yesScholaria: Jurnal Pendidikan dan Kebudayaan, 2021
Knowledge sharing has important role in establishing and maintaining the quality of any organization especially in education area. Knowledge sharing is influenced by transformational leadership which builds a culture of sharing and motivates all members
Meildy Louisa Kese, Dylmoon Hidayat
doaj  

Transformational Leadership and Knowledge Management: Analysing the Knowledge Management Models [PDF]

open access: yes, 2017
The purpose of the present study is to investigate the mutual relationship between transformational leadership and knowledge management as well the potential effects of a transformational leader on his or her followers.
Provitera, Michael J   +1 more
core   +1 more source

Calpain small subunit homodimerization is robust and calcium‐independent

open access: yesFEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy   +4 more
wiley   +1 more source

Trends of Transformational Leadership Dimensions in Indonesia Islamic Educational Institutions (2019-2024)

open access: yesAl-Ta'lim
According to Bass and Avolio, there are four dimensions of transformational leadership. These dimensions include idealized influence, inspirational motivation, intellectual stimulation, and individualized consideration.
Ratri Harida, Binti Maumah, Acmad Patoni
doaj   +1 more source

Motivational Effect of Performance Management: Does Leadership Matter?

open access: yesTransylvanian Review of Administrative Sciences, 2020
Many have expected that performance management will enhance the motivation of public employees. However, studies have reported that the motivational effect was minimal.
Hyung-Woo Lee
doaj   +1 more source

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