Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Transformational Leadership and Mentoring: Theoretical Links and Practical Implications [PDF]
Organizations are becoming increasingly aware of the advantages of generating a stream of transformational leaders who will be able to successfully move their companies into the future.
Deluga, Ronald J., St. Clair, Lynda
core +1 more source
Correlation of the differential expression of PIK3R1 and its spliced variant, p55α, in pan‐cancer
PIK3R1 undergoes alternative splicing to generate the isoforms, p85α and p55α. By combining large patient datasets with laboratory experiments, we show that PIK3R1 spliced variants shape cancer behavior. While tumors lose the protective p85α isoform, p55α is overexpressed, changes linked to poorer survival and more pronounced in African American ...
Ishita Gupta +10 more
wiley +1 more source
A conceptual framework of transformational leadership as an influential tool in the team performance
Purpose – to identify the relationship between the transformational leadership approach and team performance, to analyze the existing literature that expresses the role of transformational leadership on team performance and to create a guideline for the ...
Xhavit Islami, Enis Mulolli
doaj +1 more source
Pengaruh Kepemimpinan Transformasional Terhadap Kinerja Karyawan Pada Pt.Bank Mega Syariah Palembang [PDF]
This study aimed to examine the effect of transformational leadership to employees performance at PT Bank Mega Syariah Palembang. The sample used in this study were 39 employees with sensus method.
Wiliana, Fitri
core
Leadership and decision-making practices in public versus private universities in Pakistan [PDF]
The goal of this study is to examine differences in leadership and decision-making practices in public and private universities in Pakistan, with a focus on transformational leadership (TL) and participative decision-making (PDM).
A Brayman +40 more
core +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Ugandan hotel employee innovativeness: the role of transformational leadership and cultural intelligence [PDF]
Purpose – This study aims to determine the indirect influence of transformational leadership on cultural intelligence and employee innovativeness in the context of Ugandan hotel employees.
Moses Kisame Kisubi +2 more
doaj +1 more source
Trust in Transformational Leadership: Do Followers’ Perceptions of Leader Femininity, Masculinity, and Androgyny Matter? [PDF]
This paper takes an authenticity perspective to examine whether followers’ perceptions of a leader’s feminine, masculine, or androgynous characteristics influence the relationship between transformational leadership and followers’ perceived trust in the ...
Mustafa, Ghulam, Nazir, Babar
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In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge +17 more
wiley +1 more source

