Results 41 to 50 of about 1,199,939 (304)

Bridging the gap: Multi‐stakeholder perspectives of molecular diagnostics in oncology

Molecular Oncology, EarlyView.
Although molecular diagnostics is transforming cancer care, implementing novel technologies remains challenging. This study identifies unmet needs and technology requirements through a two‐step stakeholder involvement. Liquid biopsies for monitoring applications and predictive biomarker testing emerge as key unmet needs. Technology requirements vary by
Jorine Arnouts, Senada Koljenović, Elise Daems, Karolien De Wael, Marc Peeters, Léon C. van Kempen, Greetje Vanhoutte, Karen Zwaenepoel, Timon Vandamme   +8 more
wiley   +1 more source

Opinions of Health Employees About the Health Transformation Project

Sağlık ve Hemşirelik Yönetimi Dergisi, 2014
OBJECTIVE: This study was conducted to determine the opinions of health employees who work in public hospitals in İstanbul, about the health transformation project. METHODS: This study was cross sectional and descriptive.
Arzu Kader Harmancı Seren
doaj   +1 more source

Isospectrals of non-uniform Rayleigh beams with respect to their uniform counterparts [PDF]

Royal Society Open Science, 2018
In this paper, we look for non-uniform Rayleigh beams isospectral to a given uniform Rayleigh beam. Isospectral systems are those that have the same spectral properties, i.e. the same free vibration natural frequencies for a given boundary condition.
Srivatsa Bhat K, Ranjan Ganguli
doaj   +1 more source

Neoplastic transformation of mouse C3H 10T1/2 and Syrian hamster embryo cells by heavy ions [PDF]

, 1989
C3H 10T1/2 mouse-embryo fibroblasts were used for transformation experiments to study the effectiveness of various heavy ions with energies up to 20 MeV/u and LET values from 170 to 16.000 keV/μm.
A.M. Kellerer, Balcer-Kubiczek, Barendsen, Borek, Borek, Chomczynski, G. Ponsel, Hall, Han, Han, Hieber, Hill, K. Trutschler, Kraft, L. Hieber, Lloyd, Miller, Miller, Reznikoff, Robertson, S. Fenn, Schaeffer, Terzaghi, Wulf, Yang   +24 more
core   +1 more source

Aggressive prostate cancer is associated with pericyte dysfunction

Molecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero, Ane Martinez‐Larrinaga, Joaquim Grego‐Bessa, Saioa Garcia‐Longarte, Hielke van Splunder, Ianire Astobiza, Amaia Ercilla, Laura Bozal‐Basterra, Isabel Mendizabal, Pilar Villacampa, Arkaitz Carracedo, Mariona Graupera   +11 more
wiley   +1 more source

Selected Problems of Determining Critical Loads in Sructures with Stable Post-Critical Behaviour. [PDF]

, 2016
This paper presents selected cases of inapplicability of theory based methods of determining critical loads in thin – walled, composite tubes. 8th layered composite tubes with square cross-section were being subjected to static compression and in order ...
Czapski, Paweł, Kubiak, Tomasz
core  

Lorenz integrable system moves \`a la Poinsot

, 2003
A transformation is derived which takes Lorenz integrable system into the well-known Euler equations of a free-torque rigid body with a fixed point, i.e. the famous motion \`a la Poinsot.
Dalmedico, Hawkins, Jacobi, Kuś, Lorenz, M. C. Nucci, Marcelli, Natucci, Noether, Nucci, Nucci, Nucci, Poinsot, Rayleigh, Saltzman, Sen   +15 more
core   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Diffractive Photoproduction of Eta_c

, 2003
Diffractive photoproduction of $\eta_c$ is an important process to study the effect of Odderon, whose existence is still not confirmed in experiment.
Adloff, Adloff, Aid, Bartels, Bartels, Belitsky, Berger, Berger, Bhanot, Bodwin, Bodwin, Braun, Breakstone, Breitweg, Czyżewski, Czyżewski, Derrick, Diehl, Dosch, Eichten, Engel, Erhan, Frankfurt, Frankfurt, Frankfurt, Georgi, Grinstein, Hagler, Hoodbhoy, Isgur, Isgur, J.P. Ma, Ji, Ji, Ji, Ji, Kilian, Kuang, Kwiecinski, Lepage, Lukaszuk, Ma, Ma, Ma, Nachtmann, Peskin, Ryskin, Ryskin, Schäfer, Yan   +49 more
core   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

Molecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra, Shamsudheen Karuthedath Vellarikkal, Lixia Li, Hong Sun, Khoa Nguyen, Amber Montano, Suchitra Natarajan, Federica Piccioni, Alex Michael Tamburino, Xin Yu, Aleksandra Katarzyna Olow   +10 more
wiley   +1 more source