Results 41 to 50 of about 6,234,342 (308)
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Formation mechanism of defects in the wall of a petroleum casing steel pipe
工程科学学报, 2022 In this study, the defects in the wall of petroleum casing steel pipe were investigated. The morphology and composition of inclusions in the defects of the steel pipe were analyzed using scanning electron microscopy–energy-dispersive X-ray spectroscopy ...
Wen-kui YANG +5 more
doaj +1 more source
Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential
FEBS Letters, EarlyView.Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta +3 more
wiley +1 more source
Opinions of Health Employees About the Health Transformation Project
Sağlık ve Hemşirelik Yönetimi Dergisi, 2014 OBJECTIVE: This study was conducted to determine the opinions of health employees who work in public hospitals in İstanbul, about the health transformation project. METHODS: This study was cross sectional and descriptive.
Arzu Kader Harmancı Seren
doaj +1 more source
Annals of Medicine, 2023 To explore the transformational leadership competency of graduates from one medical university in China and its influencing variables. From 2020 to 2021, 851 medical graduates from seven hospitals affiliated with the Capital Medical University participated in this survey.
Yue Li +11 more
openaire +3 more sources
Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation
FEBS Letters, EarlyView.Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang +2 more
wiley +1 more source
ANALISIS LAYER SYSTEM BAMBU LAMINASI BERDASARKAN PENYEBARAN KERAPATAN IKATAN PEMBULUHNYA
Jurnal Ilmu Pertanian Indonesia, 2013 Anatomically, bamboo is constructed from many types of cells. Vascular bundles are the cells which give the highest contribution to the bamboo strength, thus the density distribution of vascular bundles could be used as the main variable for analyzing ...
Effendi Tri Bahtiar +4 more
doaj
Isospectrals of non-uniform Rayleigh beams with respect to their uniform counterparts [PDF]
Royal Society Open Science, 2018 In this paper, we look for non-uniform Rayleigh beams isospectral to a given uniform Rayleigh beam. Isospectral systems are those that have the same spectral properties, i.e. the same free vibration natural frequencies for a given boundary condition.
Srivatsa Bhat K, Ranjan Ganguli
doaj +1 more source
Liver organoids: modelling complexity in homeostasis and disease
FEBS Letters, EarlyView.Studying liver in vitro has been challenging because simple 2D cell cultures fail to capture liver's cellular and architectural complexity. To bridge this gap, scientists increasingly use organoids, 3D liver models which better mimic liver composition and function. This review examines recent advances in liver organoid complexity and realism, discusses
Anna M. Dowbaj, Meritxell Huch
wiley +1 more source
Epigenetic reprogramming of lineage switching in cancer
FEBS Letters, EarlyView.Cancer cells rarely commit to a single identity. Epigenetic mechanisms and tumor microenvironment cues push epithelial cells toward flexible, hybrid states that can shift into mesenchymal, neuroendocrine, or stem‐like fates, driving metastasis, drug resistance, and tumor heterogeneity. Targeting the epigenetic regulators behind these transitions, using
Ezgi Boyvatlı +4 more
wiley +1 more source