Results 41 to 50 of about 2,000,562 (345)
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source
Opinions of Health Employees About the Health Transformation Project
Sağlık ve Hemşirelik Yönetimi Dergisi, 2014 OBJECTIVE: This study was conducted to determine the opinions of health employees who work in public hospitals in İstanbul, about the health transformation project. METHODS: This study was cross sectional and descriptive.
Arzu Kader Harmancı Seren
doaj +1 more source
Isospectrals of non-uniform Rayleigh beams with respect to their uniform counterparts [PDF]
Royal Society Open Science, 2018 In this paper, we look for non-uniform Rayleigh beams isospectral to a given uniform Rayleigh beam. Isospectral systems are those that have the same spectral properties, i.e. the same free vibration natural frequencies for a given boundary condition.
Srivatsa Bhat K, Ranjan Ganguli
doaj +1 more source
Computation of the modes and polar moment of inertial of the blades of an HAWT [PDF]
, 1981 The coupled differential equations of motion of the blades of a horizontal axis wind turbine are solved numerically, permitting the optimization of the design at relatively low cost.
Beaulieu, G., Noiseux, D.
core +1 more source
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Relationship of structure and stiffness in laminated bamboo composites [PDF]
, 2018 Laminated bamboo in structural applications has the potential to change the way buildings are constructed. The fibrous microstructure of bamboo can be modelled as a fibre-reinforced composite.
core +2 more sources
Molecular Oncology, EarlyView.Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff +11 more
wiley +1 more source
Diffractive Photoproduction of Eta_c
, 2003 Diffractive photoproduction of $\eta_c$ is an important process to study the effect of Odderon, whose existence is still not confirmed in experiment.
Adloff +49 more
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Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Selected Problems of Determining Critical Loads in Sructures with Stable Post-Critical Behaviour. [PDF]
, 2016 This paper presents selected cases of inapplicability of theory based methods of determining critical loads in thin – walled, composite tubes. 8th layered composite tubes with square cross-section were being subjected to static compression and in order ...
Czapski, Paweł, Kubiak, Tomasz
core