Results 41 to 50 of about 233,638 (252)

Calpain small subunit homodimerization is robust and calcium‐independent

FEBS Letters, EarlyView.
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy, Trina Dykstra‐MacPherson, Mathias A. Bell, Peter L. Davies, Ruby May A. Sullan   +4 more
wiley   +1 more source

Transforming growth factor-β: Biology and application to cancer therapy [PDF]

Archive of Oncology, 2009
Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
doaj   +1 more source

Prognostic value of matrix metalloproteinases and transforming growth factor – β in kidney cancer

Исследования и практика в медицине, 2022
Purpose of the study. The study's objective is to investigate the expression level of tissue and serum markers of oncogenesis and nephrofibrosis transforming growth factor beta (TGF‑β) and matrix metalloproteinase‑9 (MMP‑9) in patients operated for ...
A. I. Tarasenko, A. N. Rossolovskiy, O. L. Berezinets, A. B. Bucharskaya, S. S. Pakhomiy, A. O. Efimova, G. N. Maslyakova   +6 more
doaj   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

THE ROLE OF CYTOKINES AND AGMATINE IN THE DEVELOPING PLACENTA WITH PHYSIOLOGICAL AND PREGNANCY COMPLICATED

Медицинский вестник Юга России, 2013
Purpose: To study the content of cytokines and agmatine in the development of the placenta in physiological and complicated gestation.Materials and Methods: 57 women, of which 34 women with physiological pregnancy and 23 women with placental ...
A. S. Degtyareva, I. I. Krukier, E. V. Narezhnaya, V. V. Avrutskaya, M. A. Levkovich, A. A. Nikashina   +5 more
doaj   +1 more source

Corrigendum: Transforming growth factor β1 inhibition protects from noise-induced hearing loss

Frontiers in Aging Neuroscience, 2015
Unfortunately, the second author affiliation in the originally published article was incorrectly stated as being “Centre for Biomedical Network Research (CIBER), Institute of Health Carlos III (ISCIII), Madrid, Spain.” The correct author's affiliation is “Centre for Biomedical Network Research on Rare Diseases (CIBERER), Institute of Health Carlos ...
Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Julio eContreras, Julio eContreras, Julio eContreras, Adelaida M Celaya, Adelaida M Celaya, Guadalupe eCamarero, Guadalupe eCamarero, Guadalupe eCamarero, Teresa eRivera, Teresa eRivera, Teresa eRivera, Isabel eVarela-Nieto, Isabel eVarela-Nieto, Isabel eVarela-Nieto   +19 more
openaire   +4 more sources

An isoform of 14‐3‐3 protein regulates transbilayer lipid movement at the plasma membrane

FEBS Letters, EarlyView.
Loss of 14‐3‐3ζ in CHO cells confers resistance to exogenous phosphatidylserine (PS) and impairs endocytosis‐independent inward flip‐flop of fluorescent PS at the plasma membrane. RNAi‐mediated knockdown reproduces this defect, while no additive effect is seen in ATP11C‐deficient cells.
Akiko Yamaji‐Hasegawa, Akira Hattori, Masafumi Tsujimoto, Toshihide Kobayashi   +3 more
wiley   +1 more source

TG-interacting factor is required for the differentiation of preadipocytes

Journal of Lipid Research, 2008
The accumulation of visceral adipose tissue is closely associated with insulin resistance and metabolic syndrome. Therefore, it is important to identify genes that are required for adipocyte differentiation.
Takahiro Horie, Koh Ono, Minako Kinoshita, Hitoo Nishi, Kazuya Nagao, Teruhisa Kawamura, Yukiko Abe, Hiromichi Wada, Akira Shimatsu, Toru Kita, Koji Hasegawa   +10 more
doaj   +1 more source

Additional file 1: of Partial epithelial-mesenchymal transition in keloid scars: regulation of keloid keratinocyte gene expression by transforming growth factor-β1

, 2016
Additional methods.
Hahn, Jennifer, McFarland, Kevin, Combs, Kelly, Supp, Dorothy   +3 more
openaire   +1 more source

Effect of Sini decoction on angiotensin II, transforming growth factor β1 and connective tissue growth factor in rats with myocardial fibrosis-induced banding of the abdominal aorta

Journal of Traditional Chinese Medicine, 2018
To investigate the effect of Sini decoction on rats with myocardial fibrosis induced by banding the abdominal aorta, and explore the mechanism underlying its actions on angiotensin ¢ò(Ang ¢ò), transforming growth factor-¦Â1 (TGF-¦Â1) and connective tissue growth factor (CTGF).Forty-eight male Sprague-Dawley rats were randomly divided into sham ...
Yueping, Shi, Chunxiao, Liu, Jianli, Zhai   +2 more
openaire   +2 more sources