Results 21 to 30 of about 233,638 (252)

The effect of epigallocatechin-3-gallate, a constituent of green tea, on transforming growth factor-β1–stimulated wound contraction [PDF]

Wound Repair and Regeneration, 2010
Dermal fibrosis, or scarring, following surgical incisions, traumatic wounds and burns presents a major clinical burden. Transforming growth factor (TGF)-beta1 is a major factor known to stimulate fibroblast proliferation, collagen production, and the differentiation of fibroblast to myofibroblast promoting wound contraction.
Benjamin R, Klass, Olivier A, Branford, Adriaan O, Grobbelaar, Kerstin J, Rolfe   +3 more
openaire   +2 more sources

Transforming growth factor β1 inhibition protects from noise-induced hearing loss [PDF]

Frontiers in Aging Neuroscience, 2015
Excessive exposure to noise damages the principal cochlear structures leading to hearing impairment. Inflammatory and immune responses are central mechanisms in cochlear defensive response to noise but, if unregulated, they contribute to inner ear damage and hearing loss.
Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Silvia eMurillo-Cuesta, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Lourdes eRodríguez-de La Rosa, Julio eContreras, Julio eContreras, Julio eContreras, Adelaida M Celaya, Adelaida M Celaya, Guadalupe eCamarero, Guadalupe eCamarero, Guadalupe eCamarero, Teresa eRivera, Teresa eRivera, Teresa eRivera, Isabel eVarela-Nieto, Isabel eVarela-Nieto, Isabel eVarela-Nieto   +19 more
openaire   +5 more sources

Analysis of sphingolipids in human corneal fibroblasts from normal and keratoconus patients

Journal of Lipid Research, 2017
The pathophysiology of human keratoconus (KC), a bilateral progressive corneal disease leading to protrusion of the cornea, stromal thinning, and scarring, is not well-understood.
Hui Qi, Shrestha Priyadarsini, Sarah E. Nicholas, Akhee Sarker-Nag, Jeremy Allegood, Charles E. Chalfant, Nawajes A. Mandal, Dimitrios Karamichos   +7 more
doaj   +1 more source

Korelasi Antara Transforming Growth Factor -Î’1 Monosit dengan Kebocoran Vaskuler pada Demam Berdarah Dengue

Jurnal Kedokteran Brawijaya, 2013
ABSTRAKSel monosit merupakan target utama infeksi virus Demam Berdarah Dengue (DBD) yang dapat memproduksi faktor vasoaktif yang mempengaruhi fungsi sel endotel dan berperan dalam kebocoran vaskuler. Transforming growth factor beta 1 (TGF-1) merupakan salah satu sitokin yang mempunyai banyak peran dalam patogenesis DBD.
Mohamad Supriatna, Haryson Tondy, Tatty Ermin, Yusrina Istanti, Kisdjamiatun RMD   +4 more
openaire   +1 more source

The Effects of Adipose Stem Cell–Conditioned Media on Fibrogenesis of Dermal Fibroblasts Stimulated by Transforming Growth Factor-β1 [PDF]

Journal of Burn Care & Research, 2017
Abstract Adipose-derived stem cells (ASCs) have been shown to enhance wound healing by human dermal fibroblasts; however, the interactions between ASCs and fibroblasts during injury remain unclear. Fibroblasts were treated with ASC-conditioned medium (ASC-CM) with and without transforming growth factor-β1 (TGF-β1) stimulation ...
Yuan, Bo, Broadbent, James, Huan, Jing Ning, Yang, Huizhong   +3 more
openaire   +3 more sources

Effects of Total Coronary Artery Occlusion on Vascular Endothelial Growth Factor and Transforming Growth Factor β

Kaohsiung Journal of Medical Sciences, 2005
Vascular endothelial growth factor (VEGF) and transforming growth factor β (TGF-β1) play an important role in angiogenesis. We wanted to determine if concentrations of growth factors in the coronary sinus (CS) and right atrium (RA) are higher in coronary
Tsung-Hsien Lin, Hsueh-Wei Yen, Ho-Ming Su, Wan-Ting Chien, Ye-Hsu Lu, Wen-Chol Voon, Wen-Ter Lai, Sheng-Hsiung Sheu   +7 more
doaj   +1 more source

DETEKSI KADAR TRANSFORMING GROWTH FACTOR (TGF-β) PADA LUKA AKUT

Jurnal Rekonstruksi dan Estetik, 2021
Highlights: • Peningkatan kadar TGF-β dalam fase proliferasi luka dapat berperan dalam stimulasi fibroblas untuk menghasilkan lebih banyak kolagen dalam pembentukan jaringan parut.
Pratidina Wulandari, Magda Rosalina Hutagalung, David Sontani Perdanakusuma   +2 more
doaj   +1 more source

Low Transforming Growth Factor-β Pathway Activity in Cervical Adenocarcinomas

Frontiers in Oncology, 2022
Cervical cancer is the fourth most common cancer in women worldwide. Squamous cell carcinoma (SCC) and adenocarcinoma (AC) are the most common histological types, with AC patients having worse prognosis.
Dieuwke L. Marvin, Vivian M. Spaans, Vivian M. Spaans, Cor D. de Kroon, Roderick C. Slieker, Roderick C. Slieker, Maryam Khelil, Peter ten Dijke, Laila Ritsma, Ekaterina S. Jordanova, Ekaterina S. Jordanova, Ekaterina S. Jordanova   +11 more
doaj   +1 more source

MOESM1 of Sprouty Is a Negative Regulator of Transforming Growth Factor β-Induced Epithelial-to-Mesenchymal Transition and Cataract

, 2012
Supplementary material, approximately 999 KB.
Shin, Eun, Basson, M., Robinson, Michael, McAvoy, John, Lovicu, Frank   +4 more
openaire   +1 more source

Peran transforming growth factor-`β pada reaksi eritema nodosum leprosum berulang

Media Dermato-Venereologica Indonesiana, 2019
Eritema nodosum leprosum (ENL) berulang adalah suatu komplikasi imunologi Kusta yang serius, menyebabkan peradangan pada kulit, saraf dan organ lain yang menyebabkan penurunan kualitas hidup pasien. Tujuan penelitian ini adalah untuk menelaah hubungan Transforming Growth Factor-β (TGF-β) dengan ENL berulang pada pasien kusta. Metode desain penelitian
openaire   +2 more sources