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Expression of Transforming Growth Factor-β Superfamily Receptors in Developing Rat Eyes

Japanese Journal of Ophthalmology, 1999
To ascertain the role played by the transforming growth factor (TGF)-beta superfamily in retinal development by determining the changes in the expression patterns of their receptors during development of the normal rat retina.The expression of type I and type II receptors of the TGF-beta superfamily was observed at the protein level in rat eyes at ...
H, Yamada   +3 more
openaire   +2 more sources

Transforming Growth Factor-β1 gene polymorphism and osteoporosis in postmenopausal egyptian women

Cellular and Molecular Biology, 2017
Transforming growth factor-β1 (TGF-β1) is a wide spread bone matrix protein that affect the function, formation and cell-cell interactions of osteoclasts and osteoblasts to regulate bone remodeling and sustain adequate bone mass. The aim of this study is to evaluate the role of the two polymorphism of transforming growth factor-β1 T869C and C-509T ...
Inass M, Taha   +3 more
openaire   +2 more sources

Transforming growth factor-β2 regulates C3 secretion in monocytes through a protein kinase C-dependent pathway

Molecular Immunology, 1998
Previously, we reported that TGF-beta2 regulates the C3 gene expression in a dose- and time-dependent manner in monocytes. To extend these studies, we examined the role of PKC in the TGF-beta2-mediated induction of C3 expression by the human monocyte cell line, U937.
S M, Drouin   +3 more
openaire   +2 more sources

Distribution and Expression of Transforming Growth Factor-β and Platelet-derived Growth Factor in the Normal and Glaucomatous Monkey Optic Nerve Heads

Japanese Journal of Ophthalmology, 2001
Remodeling of the extracellular matrix occurs in the lamina cribrosa in progressed glaucomatous optic nerve damage including disc cupping. We examined immunohistochemical changes in the transforming growth factor (TGF)-beta and platelet-derived growth factor (PDGF) in the optic nerve head in an experimentally induced glaucoma model.We used 3 cynomolgus
T, Fukuchi   +4 more
openaire   +2 more sources

Physiological Responses to a Natural Antioxidant Flavonoid Mixture, Silymarin, in BALB/c Mice: I Induction of Transforming Growth Factor β1 and c-myc in Liver with Marginal Effects on Other Genes

Planta Medica, 2002
Silymarin, a mixture of flavonolignans isolated from Silybum marianum, is known for its hepatoprotective properties. We investigated the expression of cytokines in mouse liver following treatment with 0, 10, 50, and 250 mg/kg of silymarin once daily for 5 days.
Quanren, He   +3 more
openaire   +2 more sources

Decorin accelerates vascular calcification via transforming growth factor-β signalling modulation

Heart, 2010
Quigley, GM   +6 more
openaire   +1 more source

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