Results 91 to 100 of about 9,205,124 (201)

Latent Transforming Growth Factor-beta1 Functionalised Electrospun Scaffolds Promote Human Cartilage Differentiation: Towards an Engineered Cartilage Construct

Archives of Plastic Surgery, 2013
Background To overcome the potential drawbacks of a short half-life and dose-related adverse effects of using active transforming growth factor-beta 1 for cartilage engineering, a cell-mediated latent growth factor activation strategy was developed ...
Erh-Hsuin Lim, Jose Paulo Sardinha, Simon Myers, Molly Stevens   +3 more
doaj   +1 more source

Intracellular expression of tumor necrosis factor alpha, interleukin 6, transforming growth factor beta1 and interleukin 10 by monocytes from healthy individuals distributed in function of the -238 promotor gene polymorphism.

, 2013
Basal and LPS-stimulated concentration of tumor necrosis factor alpha, interleukin 6, transforming growth factor beta1 and interleukin 10 on supernatants of monocyte cultures. Abbreviations: TNF-α tumor necrosis factor alpha. IL-6, interleukin 6. TGF-β1,
Clotilde Fernández-Gutiérrez (427100), Mercedes Márquez (427097), Montserrat Montes de Oca (427098), José-Antonio Girón-González (427101), Sara Corchado (427096), Paula Romero-Cores (427099)   +5 more
core   +1 more source

Empagliflozin Protects Against Proximal Renal Tubular Cell Injury Induced by High Glucose via Regulation of Hypoxia-Inducible Factor 1-Alpha

Diabetes, Metabolic Syndrome and Obesity, 2020
Angelamellisy Revelian Ndibalema,1,2 Deo Kabuye,3,4 Si Wen,1 Lulu Li,1 Xin Li,1 Qiuling Fan1 1Department of Nephrology, The First Hospital of China Medical University, Shenyang 110001, People’s Republic of China; 2Kairuki Hospital, Dar es Salaam ...
Ndibalema AR, Kabuye D, Wen S, Li L, Li X, Fan Q   +5 more
doaj  

ERK, p38, and Smad signaling pathways differentially regulate transforming growth factor-beta1 autoinduction in proximal tubular epithelial cells

, 2006
Transforming growth factor (TGF)-beta1 is a mediator of the final common pathway of fibrosis associated with progressive renal disease, a process in which proximal tubular cells (PTCs) are known to play an important part. The aim of the current study was
Donald Fraser, Mei Zhang, Aled Phillips, Zhang, M., Phillips, Aled Owain, Fraser, Donald James   +5 more
core   +1 more source

Retracted: Targeting Transforming Growth Factor-Beta1 (TGF-β1) Inhibits Tumorigenesis of Anaplastic Thyroid Carcinoma Cells Through ERK1/2-NFκB-PUMA Signaling. [PDF]

Med Sci Monit, 2022
Yin Q, Liu S, Dong A, Mi X, Hao F, Zhang K.   +5 more
europepmc   +1 more source

Regulation of transforming growth factor-beta1 by circANKS1B/miR-515-5p affects the metastatic potential and cisplatin resistance in oral squamous cell carcinoma. [PDF]

Bioengineered, 2021
Yan J, Xu H.
europepmc   +1 more source

Adeno-Associated Vector mediated gene transfer of Transforming Growth Factor-beta1 to normal and osteoarthritic human chondrocytes stimulates cartilage anabolism

European Cells & Materials, 2005
The objective of the present study was to investigate whether cartilage anabolism in human primary osteoarthritic chondrocytes could be improved by adeno-associated virus (AAV) vector-mediated gene transduction of transforming growth factor TGF-beta1 ...
Ulrich-Vinther M., Stengaard C., Schwarz E. M., Goldring M. B., Soballe K.   +4 more
doaj  

Leucine rich alpha-2-glycoprotein 1 (Lrg1) silencing protects against sepsis-mediated brain injury by inhibiting transforming growth factor beta1 (TGFβ1)/SMAD signaling pathway. [PDF]

Bioengineered, 2022
Miao Y, Wang M, Cai X, Zhu Q, Mao L.
europepmc   +1 more source

Blocking TSP1 Ameliorates Diabetes Mellitus-Induced Erectile Dysfunction by Inhibiting the TGF-β/SMAD Pathway

The World Journal of Men's Health
Purpose: To examine the role and mechanism of thrombospondin-1 (TSP1) in the development of fibrosis in diabetes mellitus- induced erectile dysfunction (DMED). Materials and Methods: DMED was induced by intraperitoneal streptozotocin injection.
Mancheng Xia, Yiming Yuan, Dong Fang, Xiaohui Tan, Fangzhou Zhao, Xinfei Li, Pengchao Gao, Zhuo Zhou, Tiegui Nan, Zhongcheng Xin, Xuesong Li, Ruili Guan   +11 more
doaj   +1 more source

Factor de crecimiento transformante beta-1: estructura, función y mecanismos de regulación en cáncer Transforming growth factor beta-1: structure, function and regulation mechanisms in cancer

Salud Pública de México, 2001
El factor de crecimiento transformante beta-1 (TGF-beta1) es sintetizado por muchas estirpes celulares como linfocitos, macrófagos y células dendríticas, y su expresión regula de manera autócrina o parácrina la diferenciación, proliferación y el estado ...
Oscar Peralta-Zaragoza, A. Lagunas-Martínez, Vicente Madrid-Marina   +2 more
doaj