Results 61 to 70 of about 9,205,124 (201)

T Cell Receptor Repertoires Across the Continuum of Vascular, Myocardial, and Age‐Related Diseases

Immunological Reviews, Volume 339, Issue 1, May 2026.
ABSTRACT Cardiovascular diseases (CVD) are shaped by a complex interplay with immune mechanisms. In particular, the distinct roles of antigen‐specific T cell mechanisms are emerging as critical determinants across a broad spectrum of conditions, ranging from atherosclerosis, myocardial infarction (MI), heart failure (HF), and myocarditis. Because these
Leon Richter, João Dias‐Ferreira, Gustavo Campos Ramos, DiyaaElDin Ashour   +3 more
wiley   +1 more source

Transforming Growth Factor‐Beta1 Gene Transfer is Associated with the Development of Regulatory Cells [PDF]

American Journal of Transplantation, 2005
Adenovirus-mediated transfection of mouse cardiac allografts with active human transforming growth factor-beta 1 (TGF-beta1) prolongs transplant survival provided that recipients are initially depleted of CD8+ T cells. To test if graft survival was prolonged by persistent TGF-beta1 transgene expression, long-term transfected allografts were re ...
Csencsits, Keri L., Wood, Sherri Chan, Lu, Guanyi, Bishop, D. Keith   +3 more
openaire   +3 more sources

Induction of gastric cancer cell adhesion through transforming growth factor-beta1-mediated peritoneal fibrosis

Journal of Experimental & Clinical Cancer Research, 2010
Background Peritoneal dissemination is one of the main causes of death in gastric cancer patients. Transforming growth factor-beta1 (TGF-β1), one of the most potent fibrotic stimuli for mesothelial cells, may play a key role in this processing.
Ma Xiao-Yang, Li Zhen, Sun Zhe, Du Zong-Min, Liu Fu-Nan, Na Di, Lv Zhi-Dong, Wang Zhen-Ning, Xu Hui-Mian   +8 more
doaj   +1 more source

AP‐1‐Targeting Decoy Oligonucleotides: Mechanisms and Therapeutic Potential as Modulators of Inflammatory Pathways

Journal of Cellular and Molecular Medicine, Volume 30, Issue 9, May 2026.
ABSTRACT Numerous cellular functions, such as apoptosis, proliferation, differentiation, survival, transformation and cell migration, are regulated by a crucial transcription factor called activator protein 1 (AP‐1). Growing evidence indicates that AP‐1 is involved in severe conditions like fibrosis, cancer, and organ damage, as well as inflammatory ...
Maryam Mahjoubin‐Tehran, Samaneh Rezaei, Vasily N. Sukhorukov, Amin Jalili, Prashant Kesharwani, Amirhossein Sahebkar   +5 more
wiley   +1 more source

Potential targets of transforming growth factor-beta1 during inhibition of oocyte maturation in zebrafish

Reproductive Biology and Endocrinology, 2005
Background TGF-beta is a multifunctional growth factor involved in regulating a variety of cellular activities. Unlike mammals, the function of TGF-beta in the reproduction of lower vertebrates, such as fish, is not clear.
Clelland Eric, Kohli Gurneet, Peng Chun
doaj   +1 more source

Differential Effects of Benralizumab and Mepolizumab on Pro‐Resolving Mediators

Allergy, Volume 81, Issue 9, Page 3377-3383, September 2026.
Jaime Bernaola, José Antonio Cañas, Álvaro Arranz‐Fragua, José Manuel Rodrigo‐Muñoz, Daniel Rodríguez‐González, Antonio Serrano‐Santiago, Gema Guillén‐Sánchez, Alma Martínez Fernández, Marcela Valverde‐Monge, Diana Betancor, Erwin Javier Pinillos‐Robles, Claudia Rodríguez‐Busto, María Jesús Rodríguez‐Nieto, Joaquín Sastre, Victoria del Pozo   +14 more
wiley   +1 more source

Cancer‐Associated Fibroblasts Functions as Multifunctional Architects of the Tumor Stroma and Represent Emerging Therapeutic Vulnerabilities

Advanced Science, Volume 13, Issue 24, 27 April 2026.
ABSTRACT Cancer‐associated fibroblasts (CAFs) are the predominant stromal components within the tumor microenvironment (TME), playing multifaceted roles in cancer progression through dynamic interactions with neoplastic and immune cells. Emerging evidence has revealed remarkable heterogeneity and plasticity of CAFs, which originate from diverse ...
Rujiao Liu, Lili Su, Shuiping Gao, Wenting Liu, Hongxia Wang   +4 more
wiley   +1 more source

Modulation of transforming growth factor beta1 gene expression in the mammary gland by insulin-like growth factor I and octreotide.

, 2000
Transforming growth factor beta1 (TGF-beta1) has been shown to exhibit anti-proliferative activity for mammary gland epithelial cells and for human breast cancer cells.
Chan, T W, Huynh, H, Pollak, M, Beamer, W   +3 more
core   +1 more source

Decreased plasma gelsolin in the COVID-19-related acute respiratory distress syndrome

Türk Biyokimya Dergisi
The aim of this study was to evaluate the potential roles of plasma gelsolin (pGSN), transforming growth factor-beta1 (TGF-β1), and lysophosphatidic acid (LPA) as profibrotic and immune modulatory markers in patients with acute respiratory distress ...
Gunturk Inayet, Seydel Gonul Seyda, Yazici Cevat, Topaloglu Ulas Serkan, Eren Esma, Yuksel Recep Civan   +5 more
doaj   +1 more source

Mild cognitive impairment‐to‐Alzheimer's dementia progression risk: the contribution of the Interceptor project

Alzheimer's &Dementia, Volume 22, Issue 4, April 2026.
Abstract BACKGROUND Mild cognitive impairment (MCI) is an intermediate stage between normal and pathological brain aging, with 30% to 50% progressing to dementia within 3 to 5 years. Early identification of individuals at high risk of progression is crucial for public health strategies.
Flavia L. Lombardo, Naike Caraglia, Patrizia Lorenzini, Nicola Vanacore, Stefano F. Cappa, Maria Cotelli, Francesco Iodice, Camillo Marra, Francesca Miraglia, Chiara Pappalettera, Daniela Perani, Davide Quaranta, Alberto Redolfi, Patrizia Spadin, Fabrizio Tagliavini, Fabrizio Vecchio, Paolo Maria Rossini, the INTERCEPTOR Network, Giacomo Tondo, Silvia De Francesco, Marcella Catania, Giacomina Rossi, Federico Cazzaniga, Cristina Muscio, Rosa Manenti, Elena Gobbi, Nicoletta Locuratolo, Antonio Ancidoni, Simone Salemme, Emanuele Cassetta, Deborah Caprara, Mario Barbagallo, Laura Vernuccio, Carlo Gabelli, Annachiara Cagnin, Mariella Casa, Simona Luzzi, Pamela Rosettani, Valentina Ranaldi, Fulvio Lauretani, Livia Ruffini, Marco Spallazzi, Innocenzo Rainero, Elisa Rubino, Carlo Ferrarese, Marco Piatti, Orazio Zanetti, Cristina Bonomini, Noemi Martellacci, Guido Maria Giuffrè, Michela Marcon, Laura Di Dionisio, Lucia Meligrana, Matteo Pardini, Federico Massa, Mattia Losa, Giuseppe Pelliccioni, Simona Castellani, Sabina Capellari, Stanzani Maserati Michelangelo, Alfredo Costa, Matteo Cotta Ramusino, Gioacchino Tedeschi, Sabrina Esposito, Carmela Gerace, Alessandro Stasolla, Laura Bonanni, Sandro Sorbi, Valentina Bessi, Carmen Morinelli, Lucilla Parnetti, Chiara Montanucci, Federico Paolini Paoletti   +72 more
wiley   +1 more source