Results 1 to 10 of about 172,191 (165)

Targeting transforming growth factor beta signaling in metastatic osteosarcoma [PDF]

Journal of Bone Oncology, 2023
Osteosarcoma is a rare type of bone cancer, and half of the cases affect children and adolescents younger than 20 years of age. Despite intensive efforts to improve both chemotherapeutics and surgical management, the clinical outcome for metastatic ...
Rongrong Ge, Gavin M. Huang
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Transforming growth factor-beta 1 enhances discharge activity of cortical neurons [PDF]

Neural Regeneration Research
Transforming growth factor-beta 1 (TGF-β1) has been extensively studied for its pleiotropic effects on central nervous system diseases. The neuroprotective or neurotoxic effects of TGF-β1 in specific brain areas may depend on the pathological process and
Zhihui Ren, Tian Li, Xueer Liu, Zelin Zhang, Xiaoxuan Chen, Weiqiang Chen, Kangsheng Li, Jiangtao Sheng   +7 more
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Transforming growth factor-beta 1 promotes endometrial fibrosis in rats [PDF]

Jichu yixue yu linchuang, 2023
Objective To investigate the expression of transforming growth factor-beta 1 in endometrial fibrosis in rats and related mechanisms. Methods Sprague-Dawley female rats were randomly divided into sham operation group (n=12) and model group (n=12)
JIN Guoyu, YANG Chunrun, HE Jing, ZHANG Shurong, LIU Huanhuan, LI Changzhong
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Using Biomimetic Scaffold Platform to Detect Growth Factor Induced Changes in Migration Dynamics of Nasopharyngeal Epithelial Cells

IEEE Access, 2020
A polydimethylsiloxane two-layer scaffold platform was designed to provide a three-dimensional biomimetic microsystem that allows the detection of epithelial-to-mesenchymal transition without the use of specific biomarkers. As a proof of concept, a novel
Bowie P. Lam, Yun Wah Lam, Stella W. Pang   +2 more
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Biological Effects of Transforming Growth Factor Beta in Human Cholangiocytes

Biology, 2022
TGF-β is a cytokine implicated in multiple cellular responses, including cell cycle regulation, fibrogenesis, angiogenesis and immune modulation. In response to pro-inflammatory and chemotactic cytokines and growth factors, cholangiocytes prime biliary ...
Elisa Ceccherini, Nicoletta Di Giorgi, Elena Michelucci, Giovanni Signore, Lorena Tedeschi, Federico Vozzi, Silvia Rocchiccioli, Antonella Cecchettini   +7 more
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Investigation of the roles of TGFβ1, CUG2, TGFBI genes, and thiol-disulfide balance on prostate cancer and metastasis

Türk Biyokimya Dergisi, 2023
Transforming growth factor-beta (TGFβ1) is involved in tumorigenesis and metastasis. It provides this effect both by disrupting the thiol-disulfide balance and through the cancer-upregulated gene (CUG2) and transforming growth factor beta-induced (TGFBI)
Tepebaşı Muhammet Yusuf, Sancer Okan, Aslan Koşar Pınar, Koşar Alim, İlhan İlter   +4 more
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The Effect of Endothelin-1 on Gene Expression of Nicotinamide Adenine Dinucleotide Phosphate (NADPH) Oxidase via Transforming Growth Factor Beta (TGF–β) Receptor in Human Aortic Smooth Muscle Cells

مجله دانشکده پزشکی اصفهان, 2018
Background: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) is one of the predominant sources of the production of free oxygen radicals in the vascular wall.
Parisa Dayati, Reyhaneh Niayesh-Mehr, Alireza Jafari, Hossein Babaahmadi-Rezaei   +3 more
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Evaluation of Serum Interleukin-17, Transforming Growth Factor-beta Levels in Brucellosis Patients Before and After Treatment

Journal of Medical Microbiology and Infectious Diseases, 2022
Introduction: Brucellosis is a zoonotic disease in humans and animals and is a worldwide public health problem. Changes in inflammatory cytokines levels might be deployed as markers for diagnosing infectious diseases from noninfectious medical ...
Roozbeh Esalatmanesh1, Mohammad Reza Sharif2, Kamal Esalatmanesh3, Shirin Heidari1, Zahra Soleimani2*   +4 more
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Transforming growth factor beta (TGF-β) in milk: a review

Revista do Instituto de Latícinios Cândido Tostes, 2016
Bovine milk and colostrum contain growth factors such as insulin-like growth factor IGF-I, IGF-II, transforming growth factor TGF-β1, TGF-β2, epidermal growth factor EGF, basic fibroblast growth factor bFGF and platelet-derived growth factor PDGF.
Fernanda Lopes da Silva, Michele da Silva Pinto, Antônio Fernandes de Carvalho, Ítalo Tuler Perrone   +3 more
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Expression of transforming growth factor beta in oral submucous fibrosis

Journal of Oral Biology and Craniofacial Research, 2020
Background: Oral submucous fibrosis (OSMF) is a premalignant condition mainly caused by areca nut chewing and is characterized by progressive fibrosis of submucosal tissues and epithelial atrophy.
Arpita Rai, Tanveer Ahmad, Shama Parveen, Saba Parveen, Md Imam Faizan, Sher Ali   +5 more
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