Results 1 to 10 of about 321,898 (257)
Targeting transforming growth factor beta signaling in metastatic osteosarcoma [PDF]
Journal of Bone Oncology, 2023 Osteosarcoma is a rare type of bone cancer, and half of the cases affect children and adolescents younger than 20 years of age. Despite intensive efforts to improve both chemotherapeutics and surgical management, the clinical outcome for metastatic ...
Rongrong Ge, Gavin M. Huang
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Recombinant Transforming Growth Factor-Beta [PDF]
Definitions, 2020 A recombinant therapeutic agent which is chemically identical to or similar to the endogenous cytokine transforming growth factor-beta (T GF-beta) with proapoptotic and antineoplastic properties. T GF-beta may suppress tumor cell growth by decreasing the
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Drug Design, Development and Therapy, 2015 Transforming growth factor-beta (TGF-β) signaling regulates a wide range of biological processes. TGF-β plays an important role in tumorigenesis and contributes to the hallmarks of cancer, including tumor proliferation, invasion and metastasis ...
M. Lahn +11 more
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Transforming growth factor-beta 1 promotes endometrial fibrosis in rats [PDF]
Jichu yixue yu linchuang, 2023 Objective To investigate the expression of transforming growth factor-beta 1 in endometrial fibrosis in rats and related mechanisms. Methods Sprague-Dawley female rats were randomly divided into sham operation group (n=12) and model group (n=12)
JIN Guoyu, YANG Chunrun, HE Jing, ZHANG Shurong, LIU Huanhuan, LI Changzhong
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Transforming Growth Factor-Beta (TGF-β) Signaling in Cancer-A Betrayal Within
Frontiers in Pharmacology, 2022 A ubiquitously expressed cytokine, transforming growth factor-beta (TGF-β) plays a significant role in various ongoing cellular mechanisms. The gain or loss-of-function of TGF-β and its downstream mediators could lead to a plethora of diseases includes ...
A. B. Baba +7 more
semanticscholar +1 more source
IEEE Access, 2020 A polydimethylsiloxane two-layer scaffold platform was designed to provide a three-dimensional biomimetic microsystem that allows the detection of epithelial-to-mesenchymal transition without the use of specific biomarkers. As a proof of concept, a novel
Bowie P. Lam +2 more
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Biological Effects of Transforming Growth Factor Beta in Human Cholangiocytes
Biology, 2022 TGF-β is a cytokine implicated in multiple cellular responses, including cell cycle regulation, fibrogenesis, angiogenesis and immune modulation. In response to pro-inflammatory and chemotactic cytokines and growth factors, cholangiocytes prime biliary ...
Elisa Ceccherini +7 more
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Türk Biyokimya Dergisi, 2023 Transforming growth factor-beta (TGFβ1) is involved in tumorigenesis and metastasis. It provides this effect both by disrupting the thiol-disulfide balance and through the cancer-upregulated gene (CUG2) and transforming growth factor beta-induced (TGFBI)
Tepebaşı Muhammet Yusuf +4 more
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مجله دانشکده پزشکی اصفهان, 2018 Background: Nicotinamide adenine dinucleotide phosphate (NADPH) oxidase (Nox) is one of the predominant sources of the production of free oxygen radicals in the vascular wall.
Parisa Dayati +3 more
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Journal of Medical Microbiology and Infectious Diseases, 2022 Introduction: Brucellosis is a zoonotic disease in humans and animals and is a worldwide public health problem. Changes in inflammatory cytokines levels might be deployed as markers for diagnosing infectious diseases from noninfectious medical ...
Roozbeh Esalatmanesh1 +4 more
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