Results 11 to 20 of about 172,191 (165)

Separation of cell survival, growth, migration, and mesenchymal transdifferentiation effects of fibroblast secretome on tumor cells of head and neck squamous cell carcinoma

open access: yesTumor Biology, 2017
Fibroblasts play a central role in tumor invasion, recurrence, and metastasis in head and neck squamous cell carcinoma. The aim of this study was to investigate the influence of tumor cell self-produced factors and paracrine fibroblast–secreted factors ...
Veronika Maria Metzler   +8 more
doaj   +1 more source

Transforming growth factor-beta and the glomerular filtration barrier

open access: yesKidney Research and Clinical Practice, 2013
The increasing burden of chronic kidney disease worldwide and recent advancements in the understanding of pathologic events leading to kidney injury have opened up new potential avenues for therapies to further diminish progression of kidney disease by ...
Ayesha Ghayur, Peter J. Margetts
doaj   +1 more source

Transforming Growth Factor-Beta (TGFβ) Signaling Pathway in Cholangiocarcinoma

open access: yesCells, 2019
Cholangiocarcinoma is a deadly cancer worldwide, associated with a poor prognosis and limited therapeutic options. Although cholangiocarcinoma accounts for less than 15% of liver primary cancer, its silent nature restricts early diagnosis and prevents ...
Panagiotis Papoutsoglou   +2 more
doaj   +1 more source

Two mutations in the transforming growth factor beta-induced gene associated with familial Lattice corneal dystrophy

open access: yesInternational Journal of Ophthalmology, 2017
AIM: To report a phenotypic variant pedigree of lattice corneal dystrophy (LCD) associated with two mutations, R124C and A546D, in the transforming growth factor beta-induced gene (TGFBI).
Wen-Ping Cao,
doaj   +1 more source

Bone remodeling at microscrew interface near extraction site in the beagle dog mandible-histologic and immunohistochemical analyses

open access: yesJournal of Applied Oral Science, 2013
Extraction is often used as part of orthodontic therapy, and good control of anchorage is a key step after extraction. Although microscrews can be implanted close to the extraction site in order to achieve orthodontic support, the efficiency of bone ...
Guangxi Wei   +5 more
doaj   +1 more source

Transforming growth factor beta (TGF-β) in adolescent chronic fatigue syndrome

open access: yesJournal of Translational Medicine, 2017
Background Chronic fatigue syndrome (CFS) is a prevalent and disabling condition among adolescent. The disease mechanisms are unknown. Previous studies have suggested elevated plasma levels of several cytokines, but a recent meta-analysis of 38 articles ...
Vegard Bruun Wyller   +3 more
doaj   +1 more source

Transforming growth factor beta 1 is associated with subclinical carotid atherosclerosis in patients with systemic lupus erythematosus

open access: yesArthritis Research & Therapy, 2023
Background Transforming growth factor beta (TGF-β1) is a multifunctional cytokine that has anti-inflammatory and immunosuppressive effects. TGF-β1 has been linked to cardiovascular disease in the general population. The immunosuppressive effect of TGF-β1
Fuensanta Gómez-Bernal   +7 more
doaj   +1 more source

A Novel Megakaryocyte Subpopulation Poised to Exert the Function of HSC Niche as Possible Driver of Myelofibrosis

open access: yesCells, 2021
Careful morphological investigations, coupled with experimental hematology studies in animal models and in in vitro human cultures, have identified that platelets are released in the circulation by mature megakaryocytes generated by hematopoietic stem ...
Anna Rita Migliaccio
doaj   +1 more source

Bisacurone gel ameliorated burn wounds in experimental rats via its anti-inflammatory, antioxidant, and angiogenic properties [PDF]

open access: yesActa Cirúrgica Brasileira, 2023
Purpose: To investigate putative mechanism of wound healing for chitosan-based bisacurone gel against secondary burn wounds in rats. Methods: A second-degree burn wound with an open flame using mixed fuel (2 mL, 20 seconds) was induced in Sprague Dawley
Zengqiang Yan, Shuyan Li, Zhenzhong Gong
doaj   +1 more source

The role of transforming growth factor beta in tertiary dentinogenesis

open access: yesDental Journal, 2008
The most visible repair response to pulp injury is the deposition of a tertiary dentin matrix over the dentinal tubules of the primary or secondary dentin.
Tetiana Haniastuti   +2 more
doaj   +1 more source

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