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Transforming growth factor-beta.
Cancer surveys, 1992This chapter has described some of the most salient features of the biology of the TGF-beta s. The TGF-beta s are of great interest as growth inhibitors, regulators of cell phenotype and regulators of cell adhesion. The various TGF-beta isoforms are highly conserved and display a complex pattern of interactions with multiple membrane receptor ...
J, Massagué +5 more
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Growth regulation by transforming growth factor-β
1993The name transforming growth factor-s (TGF-s) has come to represent a family of highly homologous polypeptides with a wide range of biological activities. The first member of this gene family was identified nearly a decade ago as one of two essential factors, called TGF-α and TGF-s present in the conditioned medium of a murine sarcoma virus-transformed
B A, Arrick, R, Derynck
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Transforming growth factor-beta (TGF-beta).
The international journal of biochemistry & cell biology, 1998The TGF-beta family of cytokines are ubiquitous, multifunctional and essential to survival. They play important roles in growth and development, inflammation and repair and host immunity. The mammalian TGF-beta isoforms (TGF-beta 1, beta 2 and beta 3) are secreted as latent precursors and have multiple cell surface receptors of which at least two ...
D A, Clark, R, Coker
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The American journal of pathology, 1992
The transforming growth factor-beta (TGF beta) family in mammals includes three closely related peptides that influence proliferation and numerous physiologic processes in most mesenchymal cells. In this study, Northern blots, immunohistochemistry, TGF beta radioreceptor assays, TGF beta receptor affinity labeling and [3H] thymidine incorporation were ...
M D, Johnson +3 more
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The transforming growth factor-beta (TGF beta) family in mammals includes three closely related peptides that influence proliferation and numerous physiologic processes in most mesenchymal cells. In this study, Northern blots, immunohistochemistry, TGF beta radioreceptor assays, TGF beta receptor affinity labeling and [3H] thymidine incorporation were ...
M D, Johnson +3 more
openaire +1 more source
The Transforming Growth Factor-beta Family
Annual Review of Cell Biology, 1990openaire +2 more sources
Transforming Growth Factor Beta and Breast Cancer
2005Virginia, Kaklamani, Boris, Pasche
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