Results 21 to 30 of about 172,191 (165)
Transforming growth factor-β: Biology and application to cancer therapy [PDF]
Archive of Oncology, 2009 Transforming growth factor-β (TGF-β), an extensively investigated cytokine, plays a very important role in promoting the spread of cancers in the body, and can play a direct role in facilitating metastasis.
Ivanović Vesna
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بررسی اثر کلسترول بر فعالسازی مسیر سیگنالینگ TGF-β / Smad3C در سلولهای ستارهای کبد و نقش آن در پیشرفت فیبروژنز کبدی [PDF]
مجله دانشکده پزشکی اصفهان, 2021 مقدمه: فیبروز کبدی، اغلب به فعال شدن سلولهای ستارهای کبد (Hepatic stellate cells یا HSCs) و تشکیل بیش از حد زخم در کبد نسبت داده میشود؛ چرا که این سلولها باعث تولید بیش از حد ماتریکس خارج سلولی میشوند.
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TGF-beta1 in breast cancer-estrogen regulation [PDF]
Archive of Oncology, 2002 TGF-beta1 is a pluripotent cytokine with diverse effects in the normal development of mammary glands, and in the development of malignant tumors of the breast.
Todorović-Raković Nataša +7 more
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Inhibition of Integrin αvβ6 Activation of TGF‐β Attenuates Tendinopathy
Advanced Science, 2022 Tendinopathy is a common tendon disorder that causes pain and impairs function. It is the most common reason for consultation with musculoskeletal specialists.
Xiao Wang +11 more
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Journal of the Egyptian Women’s Dermatologic Society, 2022 Background Systemic sclerosis is characterized by extracellular matrix overproduction by activated fibroblasts. It was reported that microRNAs (miRNAs) participate in the regulation of processes that drive fibrosis, which include transforming growth ...
Mohammed Hassan Mohammed +4 more
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Transforming growth factor beta 1, a cytokine with regenerative functions
Neural Regeneration Research, 2016 We review the biology and role of transforming growth factor beta 1 (TGF-β1) in peripheral nerve injury and regeneration, as it relates to injuries to large nerve trunks (i.e., sciatic nerve, brachial plexus), which often leads to suboptimal functional ...
Wale Sulaiman, Doan H Nguyen
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Recent Topics in Fibrodysplasia Ossificans Progressiva [PDF]
Endocrinology and Metabolism, 2018 Fibrodysplasia ossificans progressiva (FOP) is a rare genetic disease that is characterized by the formation of heterotopic bone tissues in soft tissues, such as skeletal muscle, ligament, and tendon.
Takenobu Katagiri +3 more
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Evaluation of transforming growth factor beta 1 in dogs with osteoarthritis [PDF]
Open Veterinary Journal, 2018 Osteoarthritis is a common problem in daily veterinary practice with insufficient knowledge about disease mechanism. Because fibrosis is a part of the alteration in the effected joints, we investigated the transforming growth factor beta 1 (TGF-β1) as an
Stephan Neumann, Sarah Lauenstein-Bosse
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Targeting TGFβ Signaling to Address Fibrosis Using Antisense Oligonucleotides
Biomedicines, 2018 Fibrosis results from the excessive accumulation of extracellular matrix in chronically injured tissue. The fibrotic process is governed by crosstalk between many signaling pathways.
James T. March +6 more
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Journal of Experimental & Clinical Cancer Research, 2012 Background Recent studies indicate that Transforming Growth Factor beta (TGF β) correlated with pulmonary metastasis of cancers. However, the correlation between TGF β and pulmonary metastasis of hepatocellular carcinoma (HCC) is till unknown. Methods We
Li Guo-Cai +5 more
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