Results 31 to 40 of about 172,191 (165)

Evaluation of the levels of the markers of ineffective erythropoiesis (transforming growth factor-beta, growth differentiation factor 15 and erythropoietin) in patient with ß-thalassemia syndrome and its correlation to clinical and hematological parameters

Iraqi Journal of Hematology, 2022
BACKGROUND: Anemia of β thalassemia results from a combination of ineffective erythropoiesis and hemolysis. This stimulates erythropoietin (EPO) production, which causes expansion of the bone marrow and may lead to serious deformities of the skull and ...
May Hikmat Yousif, Hind Shaker Al-Mamoori   +1 more
doaj   +1 more source

Transforming growth factor beta inhibits megakaryocyte growth and endomitosis [PDF]

Blood, 1992
Using a rat bone marrow culture system, the effect of transforming growth factor beta 1 (TGF beta 1) on megakaryocyte growth and endoreduplication has been studied. Purified human platelet TGF beta 1 inhibited the number of megakaryocytes that appeared in culture at a half-maximal concentration of 0.66 +/- 0.21 ng/mL and inhibited megakaryocyte ...
D J, Kuter, D M, Gminski, R D, Rosenberg
openaire   +3 more sources

Plasma levels of Transforming Growth Factor Beta in HIV-1 patients with oral candidiasis

Current Medical Mycology, 2015
Background and Purpose: TGF-β is a potent regulator and suppressor of the immune system and overproduction of this cytokine may contribute to immunosuppression in HIV-infected patients. Increasing population of immunosuppressed patients has resulted
Alireza Izadi, GolamReza Asadikaram, Nozar Nakhaee, Sanaz Hadizadeh, Seyyed Amin Ayatollahi Mousavi   +4 more
doaj  

Delivery of a transforming growth factor β-1 plasmid to mesenchymal stem cells via cationized Pleurotus eryngii polysaccharide nanoparticles

International Journal of Nanomedicine, 2012
Wen Wen Deng*, Xia Cao*, Miao Wang*, Rui Qu, Wei Yan Su, Yan Yang, Ya Wei Wei, Xi Ming Xu, Jiang Nan YuDepartment of Pharmaceutics, School of Pharmacy and Center for Nano Drug/Gene Delivery and Tissue Engineering, Jiangsu University, Zhenjiang, People ...
Deng WW, Cao X, Wang M, Qu R, Su WY, Yang Y, Wei YW, Xu XM, Yu JN   +8 more
doaj  

Androgens Accentuate TGF‐β Dependent Erk/Smad Activation During Thoracic Aortic Aneurysm Formation in Marfan Syndrome Male Mice

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2020
Background Male patients with Marfan syndrome have a higher risk of aortic events and root dilatation compared with females. The role androgens play during Marfan syndrome aneurysm development in males remains unknown.
Yasushi Tashima, Hao He, Jason Z. Cui, Albert J. Pedroza, Ken Nakamura, Nobu Yokoyama, Cristiana Iosef, Grayson Burdon, Tiffany Koyano, Atsushi Yamaguchi, Michael P. Fischbein   +10 more
doaj   +1 more source

Targeting transforming growth factor-β signaling [PDF]

Current Opinion in Oncology, 2007
Most cancers are characterized by excessive transforming growth factor-beta production by tumors, which can promote tumor growth and mediate epithelial-to-mesenchymal transition. Transforming growth factor-beta also has the ability to overproduce extracellular matrix components in response to injury and other stimuli.
Michael, Pennison, Boris, Pasche
openaire   +2 more sources

Comprehensive Characterization of Transforming Growth Factor Beta Receptor 1 in Stomach Adenocarcinoma Identifies a Prognostic Signature for Predicting Clinical Outcomes and Immune Infiltrates

International Journal of General Medicine, 2022
Yi He,1,* Haiyang Zhang,1,* Yan Zhang,1,2,* Peiyun Wang,1 Kegan Zhu,1 Yi Ba1 1Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, Tianjin’s Clinical Research Center for Cancer, Key ...
He Y, Zhang H, Zhang Y, Wang P, Zhu K, Ba Y   +5 more
doaj  

Diverse Biological Processes Contribute to Transforming Growth Factor β-Mediated Cancer Drug Resistance

Cells
Therapy resistance is a major obstacle to cancer treatment, and transforming growth factor-beta (TGF-β) signaling has emerged as a major instigator across many cancer types and therapeutic regimens.
James P. Heiserman, Rosemary J. Akhurst
doaj   +1 more source

Transforming growth factor beta family expression at the bovine feto-maternal interface

Reproductive Biology and Endocrinology, 2010
Background Endometrial remodelling is necessary for implantation in all mammalian species. The TGF beta super-family plays a crucial role in this event in humans and mice.
Herath Chandana B, Kizaki Keiichiro, Sugawara Kumiko, Hasegawa Yoshihisa, Hashizume Kazuyoshi   +4 more
doaj   +1 more source

Interleukin-6, vascular endothelial growth factor and transforming growth factor beta 1 in canine steroid responsive meningitis-arteritis

BMC Veterinary Research, 2013
Background Steroid Responsive Meningitis-Arteritis (SRMA) is a common cause of inflammation of the canine central nervous system (CNS). To investigate if transforming growth factor beta 1 (TGF-β1), interleukin-6 (IL-6) and vascular endothelial growth ...
Maiolini Arianna, Otten Meike, Hewicker-Trautwein Marion, Carlson Regina, Tipold Andrea   +4 more
doaj   +1 more source