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Transforming growth factor‐beta 3.
Cell Biology International, 1995ABSTRACTTransforming Growth Factor‐Beta (TGF‐β) is the general name for a family of naturally‐occurring polypeptides which have multiple regulatory effects on cell proliferation and differentiation. Over the last decade it has become apparent that TGF‐βs can be produced by most cell types and exert a wide range of effects in a context‐dependent ...
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Transforming growth factor alpha.
Cell, 1988In summary, although TGF-alpha was initially found in tumors, a number of later studies, some of them from the author's laboratory, have shown that TGF-alpha should no longer be considered a tumor associated growth factor. Rather, TGF-alpha is a normal physiological ligand for the EGF receptor.
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Epidermal Growth Factor and Transforming Growth Factor-α
1988Since its discovery in 1963 as a polypeptide that accelerated the in vivo maturation of epithelial tissues (Cohen and Elliott, 1963), epidermal growth factor (EGF) has been assumed to be important in regulating epidermal growth, differentiation, and repair.
Lillian B. Nanney, Lloyd E. King
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The transforming growth factors
Trends in Biochemical Sciences, 1985Abstract Transforming growth factors are hormonally active polypeptides that induce phenotypic transformation in normal cells. Two types of transforming growth factors, TGF-α and TGF-s, from both humans and rodents have recently been purified, characterized and cloned. With the identification of cellular receptors for TGF-α and TGF-s we now have more
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1990
Transforming growth factor-β (TGF-β) is a member of a recently discovered family of polypeptides which seem to regulate cellular activity in organisms from Drosophila to humans. Among the prominent features of this factor are its effects on extracellular matrix synthesis and maintainance and a unique capacity to exert cell-specific stimulatory ...
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Transforming growth factor-β (TGF-β) is a member of a recently discovered family of polypeptides which seem to regulate cellular activity in organisms from Drosophila to humans. Among the prominent features of this factor are its effects on extracellular matrix synthesis and maintainance and a unique capacity to exert cell-specific stimulatory ...
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Growth factors and transformation.
Cancer surveys, 1987There is ample evidence for autocrine action of growth factors in malignant transformation and for recognition of growth factor genes as proto-oncogenes. The design of new expression vectors carrying growth factor genes will permit further study of the specific effects of constitutive growth factor synthesis in cells expressing receptors for the same ...
A B, Roberts, M B, Sporn
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Cancer treatment and survivorship statistics, 2022
Ca-A Cancer Journal for Clinicians, 2022Kimberly D Miller +2 more
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