Thrombin Protease-activated Receptor-1 Signals through Gq- and G13-initiated MAPK Cascades Regulating c-Jun Expression to Induce Cell Transformation [PDF]
, 2003 Although the ability of G protein-coupled receptors to stimulate normal and aberrant cell growth has been intensely investigated, the precise nature of the molecular mechanisms underlying their transforming potential are still not fully understood.
Gutkind, J. Silvio +4 more
core +1 more source
TAK1 inhibition increases proliferation and differentiation of chick retinal cells
Frontiers in Cell and Developmental Biology, 2022 The factors necessary for the differentiation of cell types within the retina are incompletely understood. The transforming growth factor beta (TGF-β) superfamily, including TGF-β1 and 2, the bone morphogenetic proteins, and the activins have all been ...
Casandra Carrillo +4 more
doaj +1 more source
Extraction Socket Preservation Using Growth Factors and Stem Cells: a Systematic Review
eJournal of Oral Maxillofacial Research, 2019 Objectives:: To evaluate the reported literature on the use of stem cells or growth factors for post extraction treatment of the alveolar bone. Material and Methods: A NCBI PubMed and PubMed Central databases search was conducted between September ...
Mindaugas Pranskunas +2 more
doaj +1 more source
Silencing Histone Deacetylase 7 Alleviates Transforming Growth Factor-β1-Induced Profibrotic Responses in Fibroblasts Derived from Peyronie’s Plaque [PDF]
The World Journal of Men's Health, 2018 Purpose: Epigenetic modifications, such as histone acetylation/deacetylation and DNA methylation, play a crucial role in the pathogenesis of inflammatory disorders and fibrotic diseases.
Dong Hyuk Kang +9 more
doaj +1 more source
Transforming growth factor- : transforming plaque to stability [PDF]
European Heart Journal, 2012 This editorial refers to ‘Abrogated transforming growth factor beta receptor II (TGFβRII) signalling in dendritic cells promotes immune reactivity of T cells resulting in enhanced atherosclerosis’, by D. Lievens et al., doi:10.1093/eurheartj/ehs106 Lievens and colleagues report an important finding that helps to elucidate the role of transforming ...
Kevin, Tse, Klaus, Ley
openaire +2 more sources
Salivary transforming growth factor alpha in patients with Sjögren's syndrome and reflux laryngitis
Brazilian Journal of Otorhinolaryngology, 2014 Introduction: Saliva plays a key role in the homeostasis of the digestive tract, through its inorganic components and its protein growth factors.
Marco Antonio dos Anjos Corvo +5 more
doaj +1 more source
Growth factors and experimental arterial grafts [PDF]
, 2016 Background: The production of growth factors from several experimental arterial conduits was determined. Methods: We implanted 105 experimental arterial grafts that were 1 cm long in the abdominal aorta of Lewis rats (average weight, 250 g).
BORRELLI, Valeria +6 more
core +1 more source
Frontiers in Physiology, 2014 Tgfb3 is strongly and specifically expressed in the epithelial tips of pre-fusion palatal shelves where it plays a critical non-redundant role in palatal fusion in both medial edge epithelial (MEE) cells and in a thin layer of flattened peridermal cells ...
Jamie eLane +5 more
doaj +1 more source
Human stem cells and articular cartilage regeneration. [PDF]
, 2012 The regeneration of articular cartilage damaged due to trauma and posttraumatic osteoarthritis is an unmet medical need. Current approaches to regeneration and tissue engineering of articular cartilage include the use of chondrocytes, stem cells ...
Inui, Atsuyuki +2 more
core +4 more sources
Quantification of growth factors by using a new system for obtaining platelet-rich plasma [PDF]
, 2011 Objective: To verify the performance of a new method for obtaining platelet-rich plasma, while avoiding contamination of the sample during its processing. Study Design: Twenty healthy patients were selected, from whom 21 ml of blood was extracted.
Lorente Pérez-Sierra, Antonio +4 more
core +1 more source