Results 11 to 20 of about 101,508 (312)

Do postoperative infectious complications really affect long‐term survival in colorectal cancer surgery? A multicenter retrospective cohort study

open access: yesAnnals of Gastroenterological Surgery, Volume 7, Issue 1, Page 110-120, January 2023., 2023
This multicenter retrospective cohort study suggested that postoperative infection (PI) after curative colorectal surgery (CRC) is associated with impaired oncological outcomes. Strategies to prevent PI and implement appropriate postoperative treatment may improve the quality of care and oncological outcomes in patients undergoing curative CRC surgery.
Akihisa Matsuda   +18 more
wiley   +1 more source

Lovo‐cel gene therapy for sickle cell disease: Treatment process evolution and outcomes in the initial groups of the HGB‐206 study

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 11-22, January 2023., 2023
Treatment process evolution. *The target TNC for BMH was ≥6 × 108/kg per patient. The Group B1 patient received lovo‐cel produced using both the original and refined manufacturing process, and the Group B2 patient received lovo‐cel produced using only the refined manufacturing process.
Julie Kanter   +14 more
wiley   +1 more source

Romiplostim use in pregnant women with immune thrombocytopenia

open access: yesAmerican Journal of Hematology, Volume 98, Issue 1, Page 31-40, January 2023., 2023
Abstract Treatment for immune thrombocytopenia (ITP) in pregnancy is hampered by the lack of fetal safety evidence of maternally‐administered medications. The Pregnancy Surveillance Program (PSP) collected patient information from 2017–2020 for pregnancy, birth outcomes, and adverse events (AEs) for 186 women exposed to romiplostim from 20 days before ...
James B. Bussel   +7 more
wiley   +1 more source

Predicting the Need for Blood Transfusion in Intensive Care Units with Reinforcement Learning [PDF]

open access: yes, 2022
As critically ill patients frequently develop anemia or coagulopathy, transfusion of blood products is a frequent intervention in the Intensive Care Units (ICU). However, inappropriate transfusion decisions made by physicians are often associated with increased risk of complications and higher hospital costs.
arxiv   +1 more source

Acute Hemolytic Transfusion Reaction

open access: yesMedEdPORTAL, 2011
The scenario provides real-life training of acute hemolytic transfusion reaction (AHTR) in an anesthetized patient. Central to the experience is learners' ability to connect the hypotension and urine color change in an anesthetized patient to AHTR.
Mojca Konia   +2 more
doaj   +1 more source

Acute Hemolytic Transfusion Reaction

open access: yesMedEdPORTAL, 2014
This simulation scenario focuses on diagnosing and managing acute hemolytic transfusion reaction in the emergency department. It includes a novel one-page evaluation tool entitled the Simulation Training Assessment Tool (STAT) to facilitate assessment ...
Jay Baker, Luke Murphy, Ben Good
doaj   +1 more source

Phase 2 results of lisocabtagene maraleucel in Japanese patients with relapsed/refractory aggressive B‐cell non‐Hodgkin lymphoma

open access: yesCancer Medicine, Volume 11, Issue 24, Page 4889-4899, December 2022., 2022
This analysis assessed safety and efficacy of lisocabtagene maraleucel (liso‐cel), an autologous CD‐19‐directed CAR T‐cell product, in Japanese patients with R/R aggressive LBCL in Cohort 3 of TRANSCEND WORLD (NCT03484702). Liso‐cel demonstrated meaningful efficacy and a manageable safety profile in Japanese patients with R/R LBCL.
Shinichi Makita   +11 more
wiley   +1 more source

IgE- and IgG mediated severe anaphylactic platelet transfusion reaction in a known case of cerebral malaria

open access: yesAsian Journal of Transfusion Science, 2013
Background: Allergic reactions occur commonly in transfusion practice. However, severe anaphylactic reactions are rare; anti-IgA (IgA: Immunoglobulin A) in IgA-deficient patients is one of the well-illustrated and reported causes for such reactions ...
B Shanthi   +3 more
doaj   +1 more source

Red blood cell derived extracellular vesicles during the process of autologous blood doping

open access: yesDrug Testing and Analysis, Volume 14, Issue 11-12, Page 1984-1994, November-December 2022., 2022
Six, healthy volunteers donated their blood and were transfused with their red blood cell concentrate after 35–36 days of storage. RBC‐EVs showed highly significant increase (p < 0.001) from an average of 60.1 ± 19.8 (103/μL) at baseline to 179.3 ± 84.7 (103/μL) in the first 1–3 h after transfusion.
S. C. Voss   +16 more
wiley   +1 more source

Sanguine: Visual Analysis for Patient Blood Management [PDF]

open access: yes, 2020
Blood transfusion is a frequently performed medical procedure in surgical and nonsurgical contexts. Although it is frequently necessary or even life-saving, it has been identified as one of the most overused procedures in hospitals. Unnecessary transfusions not only waste resources but can also be detrimental to patient outcomes.
arxiv   +1 more source

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